Haldane and mutations (1927)

Nicolas Bacaër ()
Additional contact information
Nicolas Bacaër: IRD (Institut de Recherche pour le Développement)

Chapter Chapter 17 in A Short History of Mathematical Population Dynamics, 2011, pp 97-100 from Springer

Abstract: Abstract In another section of his 1922 article, Fisher considered the problem of a mutant gene that can be transmitted to a random number of offspring with a given probability distribution. The problem was formally the same as that of the extinction of family names but in a genetic context. Fisher showed that if the probability distribution was a Poisson distribution and if the mutant gene had no selective advantage, then the mutant gene could disappear from the population very slowly. In 1927 the British biologist Haldane pushed the study of this model further and showed that the probability of a mutant advantageous gene maintaining itself was twice its selective advantage. He also gave a more rigorous treatment of the extinction problem.

Keywords: Mutant Gene; Poisson Distribution; Selective Advantage; Extinction Probability; Indian Statistical Institute (search for similar items in EconPapers)
Date: 2011
References: Add references at CitEc
Citations:

There are no downloads for this item, see the EconPapers FAQ for hints about obtaining it.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:spr:sprchp:978-0-85729-115-8_17

Ordering information: This item can be ordered from
http://www.springer.com/9780857291158

DOI: 10.1007/978-0-85729-115-8_17

Access Statistics for this chapter

More chapters in Springer Books from Springer
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().