Basic Study Design

Lawrence M. Friedman (), Curt D. Furberg () and David L. DeMets ()
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Curt D. Furberg: Wake Forest University, School of Medicine
David L. DeMets: University of Wisconsin, Department of Biostatistics & Medical Informatics

Chapter Chapter 5 in Fundamentals of Clinical Trials, 2010, pp 67-96 from Springer

Abstract: Abstract The foundations for the design of controlled experiments were established for agricultural application. They are described in several classical statistics textbooks [1–4]. From these sources evolved the basic design of controlled clinical trials.

Keywords: Historical Control; Adaptive Design; Pragmatic Trial; Superiority Trial; Noninferiority Trial (search for similar items in EconPapers)
Date: 2010
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DOI: 10.1007/978-1-4419-1586-3_5

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