The Chain of Infection, Contacts, and Model Parametrization

Stephen Tennenbaum ()
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Stephen Tennenbaum: Mathematical, Computational and Modeling Sciences Center, Arizona State University

A chapter in Mathematical and Statistical Estimation Approaches in Epidemiology, 2009, pp 89-102 from Springer

Abstract: Abstract Contact rates and transmission probabilities are based on complicated environmental conditions, and biological and social dynamics. There are many types of models that capture different aspects of these dynamics. Estimating contact related parameter values and transmission probabilities requires a good understanding of the details of the transmission process and the class of model being used to describe it. In this paper we review the basic classes of models, the connection between the chain of infection and the descriptions of the infection process including the meaning of “contacts” in the various modeling approaches. Some suggestions as to ways to better tie together the biological and mechanistic aspects of the infection process and the more phenomenological descriptions of model parameters are discussed.

Keywords: Chain of infection; Contact rates; Mixing; Model parametrization; Modes of transmission; Portal of entry; Portal of exit; Proportionate mixing (search for similar items in EconPapers)
Date: 2009
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Persistent link: https://EconPapers.repec.org/RePEc:spr:sprchp:978-90-481-2313-1_4

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DOI: 10.1007/978-90-481-2313-1_4

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