The Analysis of Efficacy Data of Drug Trials

Ton J. Cleophas, Aeilko H. Zwinderman and Toine F. Cleophas
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Ton J. Cleophas: European Interuniversity College of Pharmaceutical Medicine Lyon
Aeilko H. Zwinderman: European Interuniversity College of Pharmaceutical Medicine Lyon
Toine F. Cleophas: Technical University

Chapter Chapter 2 in Statistics Applied to Clinical Trials, 2002, pp 17-38 from Springer

Abstract: Overview Typical efficacy endpoints have their associated statistical techniques. For example, values of continuous measurements (e.g., blood pressure) require the following statistical techniques: a. if measurements are normally distributed: t-tests and associated confidence intervals to compare two mean values; analysis of variance (ANOVA) to compare three or more. b. If measurements have a non-normal distribution: Wilcoxon rank tests with confidence intervals for medians.

Keywords: Efficacy Data; Drug Trial; Unpaired Sample; Associate Confidence Interval; Antirheumatic Agent (search for similar items in EconPapers)
Date: 2002
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DOI: 10.1007/978-94-010-0337-7_2

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