Challenges for Biometry in 21st Century Oncology

Richard Simon ()
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Richard Simon: R Simon Consulting

A chapter in Frontiers of Biostatistical Methods and Applications in Clinical Oncology, 2017, pp 1-9 from Springer

Abstract: Abstract This chapter provides an overview of the current state of translational cancer research and a discussion of some of the opportunities for biostatisticians, bioinformaticians and computational biologists to accelerate progress in the efforts to reduce cancer mortality. We describe how advances in understanding of tumor genomics have changed the development of anti-cancer treatments and stimulated the development of new clinical trial designs. We propose that further progress will require the development of treatment focused systems-biology modeling that utilizes deep sequencing data and other new tumor and immunology characterization assays. The chapter urges biometricians to participate in trans-disciplinary collaboration and maximize the impact of their contributions by investing time to understand the biological subject matter and the therapeutic context of the problems they work on.

Keywords: Translational research; Trans-disciplinary collaboration; Translational systems biology (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:spr:sprchp:978-981-10-0126-0_1

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DOI: 10.1007/978-981-10-0126-0_1

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