A Statistical Study of Platelet Size Decomposition and Related Growth Model

Ratan Dasgupta (), Koushik Biswas () and Debabrata Dash ()
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Ratan Dasgupta: Indian Statistical Institute, Theoretical Statistics and Mathematics Unit
Koushik Biswas: Medical College Hospital, Regional Institute of Ophthalmology
Debabrata Dash: Banaras Hindu University, Department of Biochemistry, Institute of Medical Sciences

A chapter in Advances in Growth Curve and Structural Equation Modeling, 2018, pp 175-193 from Springer

Abstract: Abstract We study the time-dependent distribution of blood platelet size, and its process of evolution with time, when treated with a mobile ion-carrier chemical A23187 that can penetrate into the cells causing size breakdown. The study helps to understand the role of A23187 as a carrier of drugs into cells, and to investigate signaling pathway in platelets that is of relevance in diagnosing diseases like brain stroke, diabetes, etc. It appears that the size distribution of platelets stabilizes after a time period of 3 h and more. Growth pattern of peak and ebb of the time-dependent platelet size distributions is studied to examine the stability of the process in the long run. A proportionate growth model of size breakdown is proposed.

Keywords: Blood platelet distribution; A23187; Proliferation rate; Proportionate growth model; 62P10; 65D10 (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:spr:sprchp:978-981-13-0980-9_11

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DOI: 10.1007/978-981-13-0980-9_11

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