Population toxicokinetics of ethylene: Calibration and preceding investigations

Barbara Quinke, Silvia Selinski, Klaus Golka and M. Blaszkewicz

No 2000,03, Technical Reports from Technische Universität Dortmund, Sonderforschungsbereich 475: Komplexitätsreduktion in multivariaten Datenstrukturen

Abstract: A basic step in the risk assessment of potential carcinogens is the determination of toxicokinetic parameters. The present approach is part of a strategy to determine the processes of uptake, elimination, and metabolism of the gas ethylene, an important industrial chemical, which is classified in category 3 of carcinogenic substances in the German list of MAK- and BAT-values. This paper deals with the calibration, which is indispensable to determine the decline of atmospheric concentrations of ethylene within a broad range of initial concentrations applied in an inhalation experiment.

Keywords: Ethylene; ethylene oxide; calibration; population toxicokinetics; risk assessment (search for similar items in EconPapers)
Date: 2000
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Citations: View citations in EconPapers (2)

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