MATERNAL RISK FACTORS FOR GROUP B STREPTOCOCCUS (GBS) VAGINAL COLONIZATION

Hanan H. Wahid (), Ayesha Bahez, Mohammed I. A. Mustafa Mahmud, Farih N. Hashim, Norhidayah Kamarudin, Roesnita Baharuddin, Ahmad M. Ahmad Mustafa and Hamizah Ismail
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Hanan H. Wahid: Department of Basic Medical Sciences, Kulliyyah of Medicine, International Islamic University, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200 Kuantan, Pahang Malaysia.
Ayesha Bahez: Department of Microbiology and Parasitology, Kabul University of Medical Sciences (KUMS), Karte Sakhi, Kabul, Afghanistan.
Mohammed I. A. Mustafa Mahmud: Department of Basic Medical Sciences, Kulliyyah of Medicine, International Islamic University, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200 Kuantan, Pahang Malaysia.
Farih N. Hashim: Department of Obstetrics & Gynaecology, Sultan Ahmad Shah Medical Centre @IIUM, Kulliyyah of Medicine, International Islamic University, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200 Kuantan, Pahang Malaysia.
Norhidayah Kamarudin: Department of Pathology, Sultan Ahmad Shah Medical Centre @IIUM, Kulliyyah of Medicine, International Islamic University, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200 Kuantan, Pahang Malaysia.
Roesnita Baharuddin: Department of Pathology, Hospital Tengku Ampuan Afzan, Jalan Tanah Putih, 25100 Kuantan, Pahang Malaysia.
Ahmad M. Ahmad Mustafa: Department of Obstetrics & Gynaecology, Hospital Tengku Ampuan Afzan, Jalan Tanah Putih, 25100 Kuantan, Pahang Malaysia.
Hamizah Ismail: Department of Obstetrics & Gynaecology, Sultan Ahmad Shah Medical Centre @IIUM, Kulliyyah of Medicine, International Islamic University, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200 Kuantan, Pahang Malaysia.

Acta Scientifica Malaysia (ASM), 2022, vol. 6, issue 2, 55-58

Abstract: Approximately 18% of pregnant women are colonized with Group B streptococcus (GBS), which are β-hemolytic, gram-positive bacteria. GBS conversion from the asymptomatic commensal in the vagina to an invasive pathogen predisposes the pregnant women to ascending intrauterine infection that tiggers preterm birth and initiate fetal and neonatal infections. Here, we review the prevalence of colonizing GBS serotypes and sequence types (STs) in different geographical regions. Maternal components including demographical and obstetric factors that increase the risk for GBS colonization during pregnancy are also further elucidated. The prevalence of colonizing GBS serotypes and sequence types (STs) are elucidated in this review in addition to the maternal components including demographical and obstetric factors that increase the risk for GBS colonization during pregnancy. Investigating the epidemiology is crucial for the development of new therapeutic and preventive measures to reduce the burden of invasive GBS disease worldwide including risk-factor based screening protocols.

Keywords: Group B Streptococcus; vaginal colonization; ascending intrauterine infection; preterm delivery (search for similar items in EconPapers)
Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:zib:zbnasm:v:6:y:2022:i:2:p:55-58

DOI: 10.26480/asm.02.2022.55.58

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