Beyond base pairs to bedside: A population perspective on how genomics can improve health

M.J. Khoury, M. Gwinn, M.S. Bowen and W.D. Dotson

American Journal of Public Health, 2012, vol. 102, issue 1, 34-37

Abstract: A decade after the sequencing of the human genome, the National Human Genome Research Institute announced a strategic plan forgenomicmedicine. Itcalls for evaluating the structure andbiology ofgenomes, understanding the biology of disease, advancing the science of medicine, and improving the effectiveness of health care. Fulfilling the promise of genomics urgently requires a population perspective to complement the bench-tobedside model of translation. A population approach should assess the contribution of genomics to health in the context of social and environmental determinants of disease; evaluategenomic applications that may improve health care; design strategies for integrating genomicsintopractice; address ethical, legal, and social issues; and measure the population health impact of new technologies.

Date: 2012
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Persistent link: https://EconPapers.repec.org/RePEc:aph:ajpbhl:10.2105/ajph.2011.300299_0

DOI: 10.2105/AJPH.2011.300299

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