Longitudinal effects of universal preventive intervention on prescription drug misuse: Three randomized controlled trials with late adolescents and young adults

R. Spoth, L. Trudeau, C. Shin, E. Ralston, C. Redmond, M. Greenberg and M. Feinberg

American Journal of Public Health, 2013, vol. 103, issue 4, 665-672

Abstract: Objectives: We examined long-term prescription drug misuse outcomes in 3 randomized controlled trials evaluating brief universal preventive interventions conducted during middle school. Methods: In 3 studies, we tested the Iowa Strengthening Families Program (ISFP); evaluated a revised ISFP, the Strengthening Families Program: For Parents and Youth 10-14 plus the school-based Life Skills Training (SFP 10-14 + LST); and examined the SFP 10-14 plus 1 of 3 school-based interventions. Self-reported outcomes were prescription opioid misuse (POM) and lifetime prescription drug misuse overall (PDMO). Results: In study 1, ISFP showed significant effects on POM and PDMO, relative reduction rates (RRRs; age 25 years) of 65%, and comparable benefits for higher- and lower-risk subgroups. In study 2, SFP 10-14 + LST showed significant or marginally significant effects on POM and PDMO across all ages (21, 22, and 25 years); higher-risk participants showed stronger effects (RRRs = 32%-79%). In study 3, we found significant results for POM and PDMO (12th grade RRRs = 20%-21%); higher-risk and lower-risk participants showed comparable outcomes. Conclusions: Brief universal interventions have potential for public health impact by reducing prescription drug misuse among adolescents and young adults.

Keywords: addiction; adolescent; adult; article; drug misuse; female; human; male; questionnaire; randomized controlled trial (topic); United States, Adolescent; Female; Humans; Male; Prescription Drug Misuse; Questionnaires; Randomized Controlled Trials as Topic; Substance-Related Disorders; United States; Young Adult (search for similar items in EconPapers)
Date: 2013
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Citations: View citations in EconPapers (3)

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Persistent link: https://EconPapers.repec.org/RePEc:aph:ajpbhl:10.2105/ajph.2012.301209_6

DOI: 10.2105/AJPH.2012.301209

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