Clinical uncertainties, health service challenges, and ethical complexities of hiv 'test-and-treat': A systematic review

S.P. Kulkarni, K.R. Shah, K.V. Sarma and A.P. Mahajan

American Journal of Public Health, 2013, vol. 103, issue 6, e14-e23

Abstract: Despite the HIV 'test-andtreat' strategy's promise, questions about its clinical rationale, operational feasibility, and ethical appropriateness have led to vigorous debate in the global HIV community. We performed a systematic review of the literature published between January 2009 and May 2012 using PubMed, SCOPUS, Global Health, Web of Science, BIOSIS, Cochrane CENTRAL, EBSCO Africa-Wide Information, and EBSCO CINAHL Plus databases to summarize clinical uncertainties, health service challenges, andethical complexities that may affect the test-and-treat strategy's success. A thoughtful approach to research and implementation to address clinical and health service questions and meaningful community engagement regarding ethical complexities may bring us closer to safe, feasible, and effective test-and-treat implementation.

Keywords: ethics; health care quality; health promotion; human; Human immunodeficiency virus; Human immunodeficiency virus infection; methodology; review; uncertainty, Health Promotion; HIV; HIV Infections; Humans; Program Evaluation; Uncertainty (search for similar items in EconPapers)
Date: 2013
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Citations: View citations in EconPapers (1)

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Persistent link: https://EconPapers.repec.org/RePEc:aph:ajpbhl:10.2105/ajph.2013.301273_4

DOI: 10.2105/AJPH.2013.301273

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