Life-Course accumulation of neighborhood disadvantage and allostatic load: Empirical integration of three social determinants of health frameworks

P.E. Gustafsson, S.S. Miguel, U. Janlert, T. Theorell, H. Westerlund and A. Hammarström

American Journal of Public Health, 2014, vol. 104, issue 5, 904-910

Abstract: Objectives. We examined if the accumulation of neighborhood disadvantages from adolescence to mid-adulthood were related to allostatic load, a measure of cumulative biological risk, in mid-adulthood, and explored whether this association was similar in women and men. Methods. Data were from the participants in the Northern Swedish Cohort (analytical n = 818) at ages 16, 21, 30, and 43 years in 1981, 1986, 1995, and 2008. Personal living conditions were self-reported at each wave. At age 43 years, 12 biological markers were measured to operationalize allostatic load. Registered data for all residents in the cohort participants' neighborhoods at each wave were used to construct a cumulative measure of neighborhood disadvantage. Associations were examined in ordinary least-squares regression models. Results. We found that cumulative neighborhood disadvantage between ages 16 and 43 years was related to higher allostatic load at age 43 years after adjusting for personal living conditions in the total sample (B = 0.11; P = .004) and in men (B = 0.16; P = .004), but not in women (B = 0.07; P = .248). Conclusions. Our findings suggested that neighborhood disadvantage acted cumulatively over the life course on biological wear and tear, and exemplified the gains of integrating social determinants of health frameworks.

Keywords: biological marker, adolescent; adult; article; demography; female; health disparity; human; longitudinal study; male; poverty; social determinants of health; socioeconomics; statistics; Sweden; young adult, Adolescent; Adult; Biological Markers; Female; Health Status Disparities; Humans; Longitudinal Studies; Male; Poverty; Residence Characteristics; Social Determinants of Health; Socioeconomic Factors; Sweden; Young Adult (search for similar items in EconPapers)
Date: 2014
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Citations: View citations in EconPapers (15)

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Persistent link: https://EconPapers.repec.org/RePEc:aph:ajpbhl:10.2105/ajph.2013.301707_3

DOI: 10.2105/AJPH.2013.301707

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