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Mortality hazard and survival after tuberculosis treatment

T.L. Miller, F.A. Wilson, J.W. Pang, S. Beavers, S. Hoger, S. Sharnprapai, M. Pagaoa, D.J. Katz and S.E. Weis

American Journal of Public Health, 2015, vol. 105, issue 5, 930-937

Abstract: Objectives: We compared mortality among tuberculosis (TB) survivors and a similar population. Methods: We used local health authority records from 3 USsites toidentify 3853 persons who completed adequate treatment of TB and 7282 individuals diagnosed with latent TB infection 1993 to 2002. We then retrospectively observed mortality after 6 to 16 years of observation. We ascertained vital status as of December 31, 2008, using the Centers for Disease Control and Prevention's National Death Index. We analyzed mortality rates, hazards, and associations using Cox regression. Results: We traced 11135 individuals over 119 772 person-years of observation. We found more all-cause deaths (20.7% vs 3.1%) among posttreatment TB patients than among the comparison group, an adjusted average excess of 7.6 deaths per 1000 person-years (8.8 vs 1.2; P

Keywords: adolescent; adult; aged; ancestry group; cause of death; female; HIV Infections; human; latent tuberculosis; male; middle aged; mortality; public health service; retrospective study; risk factor; statistics and numerical data; survivor; time; tuberculosis; United States; young adult, Adolescent; Adult; Aged; Cause of Death; Centers for Disease Control and Prevention (U.S.); Continental Population Groups; Female; HIV Infections; Humans; Latent Tuberculosis; Male; Middle Aged; Retrospective Studies; Risk Factors; Survivors; Time Factors; Tuberculosis; United States; Young Adult (search for similar items in EconPapers)
Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:aph:ajpbhl:10.2105/ajph.2014.302431_8

DOI: 10.2105/AJPH.2014.302431

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