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An epidemiologic postmarketing surveillance study of prescription acne medications

D.P. Facklam, J.S. Gardner, G.L. Neidert and M.M. Westland

American Journal of Public Health, 1990, vol. 80, issue 1, 50-53

Abstract: After the Food and Drug Administration approved a topical antibiotic for the treatment of acne, we began a postmarketing surveillance study to measure the frequency of antibiotic-associated colitis and diarrhea in acne patients treated with topical antibiotics and low doses of oral antibiotics. Pharmacists recruited 13,465 patients who presented a prescription for an acne medication, and we obtained detailed information on the use of the medications, perceived acceptability, and the occurrence of new health events from 6,453 with computer-assisted telephone interviews. Three cases (

Date: 1990
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