The progression of untreated HIV-1 infection prior to AIDS
Richard Murphy (),
R. Anderson and
American Journal of Public Health, 1992, vol. 82, issue 11, 1538-1541
Using a case-control study of untreated men, we investigated the physical, mental, and economic effects of human immunodeficiency virus (HIV-1) infection prior to the diagnosis of acquired immunodeficiency syndrome (AIDS). Beginning 2 to 2.5 years prior to AIDS, case subjects reported more of 12 HIV-1 related symptoms and during the year prior to AIDS, at least 30.6 extra days of these symptoms than did control subjects. Within the 6 months preceding AIDS, case subjects' unemployment rose to 9% (P ≤ .05) and depression to 34.2% (P ≤ .001). At 6 to 12 months and within 6 months before AIDS, 17.1% and 31.5%, respectively, were anemic, while 37.7% and 64.7% had CD4+ counts less than 200 x 106/L. Diagnosing AIDS at CD4+ counts less than 200 x 106/L could significantly reduce pre-AIDS morbidity. Other implications of these findings are discussed.
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Persistent link: https://EconPapers.repec.org/RePEc:aph:ajpbhl:1992:82:11:1538-1541_6
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