Neonatal tetanus in Peru: Risk assessment with modified enzyme-linked immunosorbent assay and toxoid skin test

L. Vernacchio, G. Madico, M. Verastegui, F. Diaz, T.S. Collins and R.H. Gilman

American Journal of Public Health, 1993, vol. 83, issue 12, 1754-1756

Abstract: We used a modified enzyme-linked immunosorbent assay (ELISA) to investigate tetanus immunity in 232 pregnant Peruvian women. One hundred forty-two (61.2%) had protective antitoxin titers (≥0.01 IU/mL). Protective titers correlated positively with the number of toxoid doses reported during the current pregnancy. A majority of women reporting no toxoid doses during the current pregnancy had at least one prenatal health care visit. We evaluated a toxoid skin test in 44 of the subjects, but it correlated poorly with the ELISA. The modified ELISA is a useful in vitro method for studying tetanus immunity in the developing world.

Date: 1993
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Persistent link: https://EconPapers.repec.org/RePEc:aph:ajpbhl:1993:83:12:1754-1756_0

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