Hormonal replacement therapy and morbidity and mortality in a prospective study of postmenopausal women

A.R. Folsom, P.J. Mink, T.A. Sellers, C.-P. Hong, W. Zheng and J.D. Potter

American Journal of Public Health, 1995, vol. 85, issue 8, 1128-1132

Abstract: We assessed the association of hormonal replacement therapy with mortality and incidence of multiple diseases in over 40 000 postmenopausal women followed for 6 years as part of the Iowa Women's Health Study. Compared with women who never used hormone replacement therapy, current users had multivariate adjusted relative risks (RR) as follows: total mortality (RR = 0.78; 95% confidence interval [CI] = 0.65, 0.94), coronary heart disease mortality (RR = 0.74; 95% CI = 0.48, 1.12), endometrial cancer incidence (RR = 4.3; 95% CI = 2.7, 6.9), breast cancer incidence (RR = 1.23; 95% CI = 0.99, 1.55), colon cancer incidence (RR = 0.72; 95% CI = 0.46, 1.12), and hip fracture incidence (RR = 0.53; 95% CI = 0.31, 0.91).

Date: 1995
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Persistent link: https://EconPapers.repec.org/RePEc:aph:ajpbhl:1995:85:8:1128-1132_1

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