Characterization of Three-Dimensional Structures of Collagen Extracted from the Umbilical-Placental Complex for Applications in Oral-Maxillofacial Surgery

Mariana Jian, Oleg Solomon, Andrei Mostovei, Ovidiu Cristian Oprea, Ludmila Motelica, Ana-Maria Nacu, Vitalie Cobzac, Denisa Ficai, Anton Ficai and Viorel Nacu

Intellectus, 2024, issue 1, 179-188

Abstract: This paper is focused on the study of the three-dimensional structures of collagen extracted from the umbilical-placental complex with the aim of use in oral-maxillofacial surgery. Collagen was extracted from the umbilical-placental complex by a modified enzymatic method that involves initial purification with different surfactants to remove blood and cellular components and ensure non-immunogenicity. The null hypothesis of the concerned works consists in the fact that the surfactants used do not act on the collagen structures. Three-dimensional collagen structures were developed by the lyophilization process and were analyzed by scanning electron microscopy, Young's modulus (elasticity), thermogravimetry and Fourier transform infrared spectroscopy and microscopy.

Keywords: placenta; collagen; umbilical cord; oral-maxillofacial surgery; bone regeneration. (search for similar items in EconPapers)
Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:awf:journl:y:2024:i:1:p:179-188

DOI: 10.56329/1810-7087.24.1.17

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