Combining Nearest Neighbor Classifiers Versus Cross-Validation Selection

Paik Minhui and Yang Yuhong
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Paik Minhui: Iowa State University
Yang Yuhong: Iowa State University

Statistical Applications in Genetics and Molecular Biology, 2004, vol. 3, issue 1, 21

Abstract: Various discriminant methods have been applied for classification of tumors based on gene expression profiles, among which the nearest neighbor (NN) method has been reported to perform relatively well. Usually cross-validation (CV) is used to select the neighbor size as well as the number of variables for the NN method. However, CV can perform poorly when there is considerable uncertainty in choosing the best candidate classifier. As an alternative to selecting a single ``winner,'' we propose a weighting method to combine the multiple NN rules. Four gene expression data sets are used to compare its performance with CV methods. The results show that when the CV selection is unstable, the combined classifier performs much better.

Keywords: combining classifiers; nearest neighbor method; cross-validation (search for similar items in EconPapers)
Date: 2004
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Citations: View citations in EconPapers (1)

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DOI: 10.2202/1544-6115.1054

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