Assessing the potential of pre-exposure vaccination and chemoprophylaxis in the control of lymphatic filariasis

C.P. Bhunu

Applied Mathematics and Computation, 2015, vol. 250, issue C, 571-579

Abstract: An epidemiological model to assess the potential impact of pre-exposure vaccines and other intervention strategies on lymphatic filariasis is proposed and investigated. The threshold parameter of the model is computed and rigorously analysed. Results from model analysis suggests that vaccination at birth and pre-exposure vaccination will aid in reducing lymphatic filariasis disease burden. However, results further suggest that chemoprophylaxis or mosquito spraying alone may be able to keep lymphatic filariasis infections in check. Numerical simulations also show that treatment alone will not be able control the spread of lymphatic filariasis. Furthermore, results from numerical simulations suggest that treatment for the sick in addition to chemoprophylaxis for the exposed may be able to effectively control the spread of lymphatic filariasis.

Keywords: Epidemiological model; Threshold parameter; Numerical simulations (search for similar items in EconPapers)
Date: 2015
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
http://www.sciencedirect.com/science/article/pii/S0096300314015409
Full text for ScienceDirect subscribers only

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:eee:apmaco:v:250:y:2015:i:c:p:571-579

DOI: 10.1016/j.amc.2014.11.018

Access Statistics for this article

Applied Mathematics and Computation is currently edited by Theodore Simos

More articles in Applied Mathematics and Computation from Elsevier
Bibliographic data for series maintained by Catherine Liu ().