Characterization of micro-capsules deformation in branching channels
A. Coclite,
M.D. de Tullio,
G. Pascazio and
T. Politi
Applied Mathematics and Computation, 2022, vol. 434, issue C
Abstract:
In this paper, the dynamic of inertial capsules into microfluidic bifurcations is studied. The fluid evolution is based on the solution of the BGK – lattice Boltzmann scheme including a forcing term accounting for immersed geometries. The dynamic-Immersed Boundary forcing strategy is adopted for imposing no-slip boundary conditions on moving deformable or rigid structures, while, on fixed immersed geometries the Bouzidi–Firdaouss–Lallemand second-order bounce back technique is implemented. The proposed computational framework is employed to detail dynamics and deformation of rigid and deformable capsules traveling into a branching duct. This journey is characterized in terms of i) the capsule/bifurcation interaction depending on the sharpness of the branching channels junction; ii) daughter branches aperture angle; iii) occlusion ratio, the ratio between capsule size and main channel diameter; iv) flowing capsules stiffness; v) number of flowing particles.
Keywords: Dynamic immersed boundary; Lab on a chip; Microfluidics bifurcations; Cell transport; Moving least squares (search for similar items in EconPapers)
Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:eee:apmaco:v:434:y:2022:i:c:s0096300322005197
DOI: 10.1016/j.amc.2022.127445
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