Computing the threshold of the influence of intercellular nanotubes on cell-to-cell communication integrity

Dragutin T. Mihailović, Vladimir R. Kostić, Igor Balaž and Darko Kapor

Chaos, Solitons & Fractals, 2016, vol. 91, issue C, 174-179

Abstract: We explore how the biochemical substance exchange through tunneling nanotubes (TNTs) affects the functional stability of a multicellular system. We focus on two questions: whether TNTs can either stabilize or destabilize intercellular communication governed by gap junctions (GJs)? and how to determine the threshold at which influence of TNTs destabilize GJ-mediated communication? The goal of this article is to introduce the way in which the concept of pseudospectra can be used to provide the answers.

Keywords: Nanotubes; Gap junctions; Pseudospectrum; Stability (search for similar items in EconPapers)
Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:eee:chsofr:v:91:y:2016:i:c:p:174-179

DOI: 10.1016/j.chaos.2016.06.001

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