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Living with influenza: Impacts of government imposed and voluntarily selected interventions

Karima R. Nigmatulina and Richard C. Larson

European Journal of Operational Research, 2009, vol. 195, issue 2, 613-627

Abstract: Focusing on mitigation strategies for global pandemic influenza, we use elementary mathematical models to evaluate the implementation and timing of non-pharmaceutical intervention strategies such as travel restrictions, social distancing and improved hygiene. A spreadsheet model of infection spread between several linked heterogeneous communities is based on analytical calculations and Monte Carlo simulations. Since human behavior will likely change during the course of a pandemic, thereby altering the dynamics of the disease, we incorporate a feedback parameter into our model to reflect altered behavior. Our results indicate that while a flu pandemic could be devastating; there are coping methods that when implemented quickly and correctly can significantly mitigate the severity of a global outbreak.

Keywords: Stochastic; modeling; Pandemic; flu; OR; in; health; services; Heterogeneity; Behavior (search for similar items in EconPapers)
Date: 2009
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Citations: View citations in EconPapers (11)

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European Journal of Operational Research is currently edited by Roman Slowinski, Jesus Artalejo, Jean-Charles. Billaut, Robert Dyson and Lorenzo Peccati

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