Optimizing the simultaneous management of blood pressure and cholesterol for type 2 diabetes patients

J.E. Mason, B.T. Denton, N.D. Shah and S.A. Smith

European Journal of Operational Research, 2014, vol. 233, issue 3, 727-738

Abstract: We present a Markov decision process (MDP) model to determine the optimal timing of blood pressure and cholesterol medications. We study the use of our model for a high-risk population of patients with type 2 diabetes; however, the model and methods we present are applicable to the general population. We compare the optimal policies based on our MDP to published guidelines for initiation of blood pressure and cholesterol medications over the course of a patient’s lifetime. We also present a bicriteria analysis that illustrates the trade off between quality-adjusted life years and costs of treatment.

Keywords: OR in medicine; Markov decision process; Type 2 diabetes; Blood pressure treatment; Cholesterol treatment (search for similar items in EconPapers)
Date: 2014
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Citations: View citations in EconPapers (15)

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Persistent link: https://EconPapers.repec.org/RePEc:eee:ejores:v:233:y:2014:i:3:p:727-738

DOI: 10.1016/j.ejor.2013.09.018

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