Recycled incomplete identification procedures for blood screening

Shaul K. Bar-Lev, Onno Boxma, Igor Kleiner, David Perry and Wolfgang Stadje

European Journal of Operational Research, 2017, vol. 259, issue 1, 330-343

Abstract: The operation of blood banks aims at the cost-efficient supply of uncontaminated human blood. Each unit of donated blood goes through multiple testing for the presence of various pathogens which are able to cause transfusion-transmitted diseases. The blood screening process is comprised of two phases. At the first phase, blood units are screened together in pooled groups of a certain size by the ELISA (Enzyme Linked Immuno-Sorbent Assay) test to detect various virus-specific antibodies. The second phase of the screening process is conducted by PCR (Polymerase Chain Reaction) testing of the individual blood units of the groups found clean by the initial ELISA phase.

Keywords: Group testing; Blood screening; Markov chain; Combinatorial urn problems; Recycled group testing (search for similar items in EconPapers)
Date: 2017
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Citations: View citations in EconPapers (2)

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Persistent link: https://EconPapers.repec.org/RePEc:eee:ejores:v:259:y:2017:i:1:p:330-343

DOI: 10.1016/j.ejor.2016.10.005

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