Complex biological models: Their construction and effective use

David Garfinkel

Mathematics and Computers in Simulation (MATCOM), 1982, vol. 24, issue 6, 425-429

Abstract: The need for complex models in biology, and reasons such as esthetics and tradition for resistance to their use, are discussed. Examples considered are an existing cardiac metabolism model, and a possible comprehensive and complex diabetes model, with their associated problems. Characteristic problems of complex modeling include how complex a model should be, combination and interaction of models from different sources, the kind of underlying information involved, and the usual problems of model credibility. Specific problems of biological modeling include: effective interaction with experimenters to secure timely solution of currently important problems, (e.g., by experimental design), and effective interaction within the community of biological modelers.

Date: 1982
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Persistent link: https://EconPapers.repec.org/RePEc:eee:matcom:v:24:y:1982:i:6:p:425-429

DOI: 10.1016/0378-4754(82)90638-3

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