Lipid chain packing and lipid-protein interaction in membranes

Deborah R. Fattal and Avinoam Ben-Shaul

Physica A: Statistical Mechanics and its Applications, 1995, vol. 220, issue 1, 192-216

Abstract: This article describes briefly several applications of a molecular theory of lipid organization in membranes to systems of biophysical interest. After introducing the basic concepts of this mean field theory we outline three of its recent applications. i) Calculations of lipid chain conformational statistics in membrane bilayers, and comparison of the results (e.g. bond orientational order parameters) to experiment and molecular dynamics simulations. Good agreement is found. ii) A molecular model for lipid-protein interactions, which explicitly considers the effects of a rigid hydrophobic protein on the elastic (conformational) properties of the lipid bilayer. We also analyze the role of the ‘hydrophobic mismatch’ between the protein and lipid bilayer thickness. iii) A molecular level calculation of the vesicle to micelle transition, attendant upon the addition of (‘curvature loving’) surfactant to a lipid bilayer vesicle. Future applications, e.g. to the calculation of the free energy barriers involved in membrane fusion are briefly mentioned.

Date: 1995
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
http://www.sciencedirect.com/science/article/pii/037843719500117P
Full text for ScienceDirect subscribers only. Journal offers the option of making the article available online on Science direct for a fee of $3,000

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:220:y:1995:i:1:p:192-216

DOI: 10.1016/0378-4371(95)00117-P

Access Statistics for this article

Physica A: Statistical Mechanics and its Applications is currently edited by K. A. Dawson, J. O. Indekeu, H.E. Stanley and C. Tsallis

More articles in Physica A: Statistical Mechanics and its Applications from Elsevier
Bibliographic data for series maintained by Catherine Liu ().