Statistical physics and Alzheimer’s disease

H.Eugene Stanley, Sergey V Buldyrev, Luis Cruz, Teresa Gomez-Isla, Shlomo Havlin, Bradley T Hyman, Roger Knowles, Brigita Urbanc and Claire Wyart

Physica A: Statistical Mechanics and its Applications, 1998, vol. 249, issue 1, 460-471

Abstract: We discuss the possible utility of statistical physics in elucidating some of the puzzling phenomena that seem to occur in the brains of patients affected with Alzheimer’s disease. Further, we report three specific results from this approach: (i) The size distribution of senile plaques appears to be log-normal, (ii) We develop a model for growth of senile plaques that is characterized by both aggregation and disaggregation, and (iii) We quantify neuron architecture and find quantitative evidence for the existence of microcolumns positioned at right angles to the known lamina.

Date: 1998
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Citations: View citations in EconPapers (2)

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Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:249:y:1998:i:1:p:460-471

DOI: 10.1016/S0378-4371(97)00548-7

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