Effect of cellular mobility on immune response

R.b Pandey, R Mannion and H.j Ruskin

Physica A: Statistical Mechanics and its Applications, 2000, vol. 283, issue 3, 447-450

Abstract: Mobility of cell types in our HIV immune response model is subject to an intrinsic mobility and an explicit directed mobility, which is governed by Pmob. We investigate how restricting the explicit mobility, while maintaining the innate mobility of a viral-infected cell, affects the model's results. We find that increasing the explicit mobility of the immune system cells leads to viral dominance for certain levels of viral mutation. We conclude that increasing immune system cellular mobility indirectly increases the virus’ inherent mobility.

Keywords: HIV modelling; Mobility (search for similar items in EconPapers)
Date: 2000
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Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:283:y:2000:i:3:p:447-450

DOI: 10.1016/S0378-4371(00)00206-5

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