Spontaneous synchronized bursting in 2D neural networks

Ronen Segev and Eshel Ben-Jacob

Physica A: Statistical Mechanics and its Applications, 2001, vol. 302, issue 1, 64-69

Abstract: We present a long-term (hours) measurements of the spontaneous activity of cortical cells 2D neural network placed on multi-electrodes arrays. We compare the histogram of the single neurons inter spike interval and the network inter synchronized bursting events interval. In addition, the effect of Ca concentration on the network activity is being studied. Under 1mMCa concentration the network exhibits periodic synchronized bursting. We present a novel feedback regulated integrate & fire model to account of the observations. In the model we include two additional features of dynamical threshold and synapses fatigue.

Keywords: Neural networks; Synchronized bursting; In vitro (search for similar items in EconPapers)
Date: 2001
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Citations: View citations in EconPapers (1)

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Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:302:y:2001:i:1:p:64-69

DOI: 10.1016/S0378-4371(01)00441-1

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