Destructuring effect of trehalose on the tetrahedral network of water: a Raman and neutron diffraction comparison

C. Branca, S. Magazù, F. Migliardo and P. Migliardo

Physica A: Statistical Mechanics and its Applications, 2002, vol. 304, issue 1, 314-318

Abstract: Results on trehalose/water solutions by neutron diffraction are reported. The analysis of the partial structure factors obtained by neutron diffraction on trehalose/water solutions is interpreted in terms of a destructuring effect of trehalose on the tetrahedral H-bond network of water. This hypothesis, suggested by a previous analysis of the Raman intramolecular OH stretching band, can account for the greater cryoprotective action of trehalose on biological structures.

Keywords: Aqueous solution; Neutron diffraction (search for similar items in EconPapers)
Date: 2002
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Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:304:y:2002:i:1:p:314-318

DOI: 10.1016/S0378-4371(01)00517-9

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