The topology of the transcription regulatory network in the yeast, Saccharomyces cerevisiae

I. Farkas, H. Jeong, T. Vicsek, A.-L. Barabási and Z.N. Oltvai

Physica A: Statistical Mechanics and its Applications, 2003, vol. 318, issue 3, 601-612

Abstract: A central goal of postgenomic biology is the elucidation of the regulatory relationships among all cellular constituents that together comprise the ‘genetic network’ of a cell or microorganism. Experimental manipulation of gene activity coupled with the assessment of perturbed transcriptome (i.e., global mRNA expression) patterns represents one approach toward this goal, and may provide a backbone into which other measurements can be later integrated.

Keywords: Bioinformatics; mRNA expression; Analysis of graph topology (search for similar items in EconPapers)
Date: 2003
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (10)

Downloads: (external link)
http://www.sciencedirect.com/science/article/pii/S0378437102017314
Full text for ScienceDirect subscribers only. Journal offers the option of making the article available online on Science direct for a fee of $3,000

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:318:y:2003:i:3:p:601-612

DOI: 10.1016/S0378-4371(02)01731-4

Access Statistics for this article

Physica A: Statistical Mechanics and its Applications is currently edited by K. A. Dawson, J. O. Indekeu, H.E. Stanley and C. Tsallis

More articles in Physica A: Statistical Mechanics and its Applications from Elsevier
Bibliographic data for series maintained by Catherine Liu ().