Melting transition of directly linked gold nanoparticle DNA assembly

Y. Sun, N.C. Harris and C.-H. Kiang

Physica A: Statistical Mechanics and its Applications, 2005, vol. 350, issue 1, 89-94

Abstract: DNA melting and hybridization is a fundamental biological process as well as a crucial step in many modern biotechnology applications. DNA confined on surfaces exhibits a behavior different from that in free solutions. The system of DNA-capped gold nanoparticles exhibits unique phase transitions and represents a new class of complex fluids. Depending on the sequence of the DNA, particles can be linked to each other through direct complementary DNA sequences or via a ‘linker’ DNA, whose sequence is complementary to the sequence attached to the gold nanoparticles. We observed different melting transitions for these two distinct systems.

Keywords: DNA phase transition; Gold nanoparticle; DNA melting (search for similar items in EconPapers)
Date: 2005
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Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:350:y:2005:i:1:p:89-94

DOI: 10.1016/j.physa.2005.01.013

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