Driven translocation dynamics of polynucleotides through a nanopore: off-lattice Monte-Carlo simulations

C.-M. Chen

Physica A: Statistical Mechanics and its Applications, 2005, vol. 350, issue 1, 95-107

Abstract: The driven translocation dynamics of a polynucleotide chain through a nanopore is studied using off-lattice Monte-Carlo simulations, which plays an important role in the nanopore sequencing of polynucleotides. We report a detailed study on the dependence of translocation dynamics on the chain length and the local geometry near the nanopore. In particular, we find that the length dependence of the infection time of the chain could exhibit very different behaviors for different geometries.

Date: 2005
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Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:350:y:2005:i:1:p:95-107

DOI: 10.1016/j.physa.2004.11.026

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