A cell-centered approach to developmental biology

Roeland M.H. Merks and James A. Glazier

Physica A: Statistical Mechanics and its Applications, 2005, vol. 352, issue 1, 113-130

Abstract: Explaining embryonic development of multicellular organisms requires insight into complex interactions between genetic regulation and physical, generic mechanisms at multiple scales. As more physicists move into developmental biology, we need to be aware of the “cultural” differences between the two fields, whose concepts of “explanations” and “models” traditionally differ: biologists aiming to identify genetic pathways and expression patterns, physicists tending to look for generic underlying principles.

Keywords: Computational biology; Cellular Potts Model; Cell-oriented modeling; Biological ontologies; Developmental biology (search for similar items in EconPapers)
Date: 2005
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Citations: View citations in EconPapers (4)

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Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:352:y:2005:i:1:p:113-130

DOI: 10.1016/j.physa.2004.12.028

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