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Local and global responses in complex gene regulation networks

Masa Tsuchiya, Kumar Selvarajoo, Vincent Piras, Masaru Tomita and Alessandro Giuliani

Physica A: Statistical Mechanics and its Applications, 2009, vol. 388, issue 8, 1738-1746

Abstract: An exacerbated sensitivity to apparently minor stimuli and a general resilience of the entire system stay together side-by-side in biological systems. This apparent paradox can be explained by the consideration of biological systems as very strongly interconnected network systems. Some nodes of these networks, thanks to their peculiar location in the network architecture, are responsible for the sensitivity aspects, while the large degree of interconnection is at the basis of the resilience properties of the system.

Keywords: Biological statistical mechanics; Systems biology; Cell cultures; Networks (search for similar items in EconPapers)
Date: 2009
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Citations: View citations in EconPapers (3)

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Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:388:y:2009:i:8:p:1738-1746

DOI: 10.1016/j.physa.2008.12.030

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Physica A: Statistical Mechanics and its Applications is currently edited by K. A. Dawson, J. O. Indekeu, H.E. Stanley and C. Tsallis

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