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Folding kinetics of two-state proteins based on the model of general random walk in native contact number space

J.S. Guo, D. Mi and Y.Q. Sun

Physica A: Statistical Mechanics and its Applications, 2010, vol. 389, issue 4, 761-766

Abstract: We investigated the folding kinetics of a series of two-state proteins by using the model of general random walk in native contact number space, and derive the observed linear relationship between the logarithms of the folding rate constants and the numbers of native contacts from “kinetic viewpoint”. The protein folding speed limit and stability in this model are consistent with experimental observations.

Keywords: Protein folding; Folding rate; Native contact; Folding kinetics; Random walk model (search for similar items in EconPapers)
Date: 2010
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Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:389:y:2010:i:4:p:761-766

DOI: 10.1016/j.physa.2009.10.026

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