Cellular automata models of tumour natural shrinkage

Lev Naumov, Alfons Hoekstra and Peter Sloot

Physica A: Statistical Mechanics and its Applications, 2011, vol. 390, issue 12, 2283-2290

Abstract: In this paper we present three dimensional cellular automata models for tumour growth, with a focus on the tumour’s natural shrinkage caused by the removal of the dead cells’ mortal remains. The significance of this phenomenon for the resulting volume of the in silico tumour is shown. Two algorithms are presented, one using the chain shifting approach for tumour expansion and shrinkage and another improving the performance of the chain shifting approach. Simulations are validated against the experimental results.

Keywords: Cellular automaton; Tumour; Cell; Shrinkage; Computational biology (search for similar items in EconPapers)
Date: 2011
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Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:390:y:2011:i:12:p:2283-2290

DOI: 10.1016/j.physa.2011.02.006

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