Irreversibility indices as discriminators of heart conditions from Electrocardiographic signals

Cesar Maldonado and Merino–Negrete, Nazul

Physica A: Statistical Mechanics and its Applications, 2024, vol. 637, issue C

Abstract: We estimate the entropy production rate and the Kullback–Leibler divergence in discrete time series of electrocardiographic and the RR-interval signals of healthy and unhealthy patients. We show that these indices of irreversibility, applied directly to the electrocardiographic signals, may be used as a tool for discrimination between healthy subjects and patients with heart conditions. We test our method in a controlled Markov chain model. Finally, we test the performance of our methodology of discrimination by quantifying its accuracy using ROC analysis.

Keywords: Entropy production rate; Kullback–Leibler divergence; Electrocardiograms; Heart rate variability; Irreversibility in time series (search for similar items in EconPapers)
Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:eee:phsmap:v:637:y:2024:i:c:s037843712400092x

DOI: 10.1016/j.physa.2024.129584

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