Scratching the surface: Exploratory analysis of key opinion leaders on rate limiting factors in novel adjuvanted-vaccine development

Esther Pronker, Tamar Weenen, Harry Commandeur, E. Claassen and A.D.M.E. Osterhaus

Technological Forecasting and Social Change, 2015, vol. 90, issue PB, 420-432

Abstract: This exploratory qualitative article analyzes the potentially rate-limiting factors affecting value chain dynamics during adjuvanted-vaccine development. Adjuvants are considered immunostimulating substances that can be added to a vaccine. Although adjuvants have the potential to elicit adverse reactions, they also offer certain benefits. After approximately 90years of R&D, why have only four adjuvants been approved? Although ample literature is available describing the risks and benefits, it remains unclear as to how these potentially rate-limiting factors compare.

Keywords: Adjuvanted-vaccine; Research and development; Rate-limiting factors; Key opinion leader; Principal–agent theory; Qualitative interview (search for similar items in EconPapers)
Date: 2015
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Citations: View citations in EconPapers (3)

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Persistent link: https://EconPapers.repec.org/RePEc:eee:tefoso:v:90:y:2015:i:pb:p:420-432

DOI: 10.1016/j.techfore.2014.04.017

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