Relationship inference from the genetic data on parents or offspring: A comparative study

Steven Gazal, Génin, Emmanuelle and Anne-Louise Leutenegger

Theoretical Population Biology, 2016, vol. 107, issue C, 31-38

Abstract: Relationship inference in a population is of interest for many areas of research from anthropology to genetics. It is possible to directly infer the relationship between the two individuals in a couple from their genetic data or to indirectly infer it from the genetic data of one of their offspring. For this reason, one can wonder if it is more advantageous to sample couples or single individuals to study relationships of couples in a population. Indeed, sampling two individuals is more informative than sampling one as we are looking at four haplotypes instead of two, but it also doubles the cost of the study and is a more complex sampling scheme.

Keywords: Relationship inference; Mating habit; Identity-by-descent; Kinship coefficient; Inbreeding coefficient; Genome sharing (search for similar items in EconPapers)
Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:eee:thpobi:v:107:y:2016:i:c:p:31-38

DOI: 10.1016/j.tpb.2015.09.002

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