Effect of Inorganic Zinc on Selected Immune Parameters in Chicken Blood and Jejunum after A. galli Infection

Viera Karaffová, Viera Revajová, Emília Dvorožňáková, Ľubomíra Grešáková, Martin Levkut, Zuzana Ševčíková, Róbert Herich and Mikulas Levkut
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Viera Karaffová: Department of Morphological Disciplines, University of Veterinary Medicine and Pharmacy, Komenského, 73041 81 Košice, Slovakia
Viera Revajová: Department of Morphological Disciplines, University of Veterinary Medicine and Pharmacy, Komenského, 73041 81 Košice, Slovakia
Emília Dvorožňáková: Institute of Parasitology, Slovak Academy of Sciences, Hlinkova, 3040 01 Košice, Slovakia
Ľubomíra Grešáková: Institute of Animal Physiology Centre of Biosciences of the Slovak, Academy of Sciences, Šoltésovej, 4040 01 Košice, Slovakia
Martin Levkut: Department of Morphological Disciplines, University of Veterinary Medicine and Pharmacy, Komenského, 73041 81 Košice, Slovakia
Zuzana Ševčíková: Department of Morphological Disciplines, University of Veterinary Medicine and Pharmacy, Komenského, 73041 81 Košice, Slovakia
Róbert Herich: Department of Morphological Disciplines, University of Veterinary Medicine and Pharmacy, Komenského, 73041 81 Košice, Slovakia
Mikulas Levkut: Department of Morphological Disciplines, University of Veterinary Medicine and Pharmacy, Komenského, 73041 81 Košice, Slovakia

Agriculture, 2021, vol. 11, issue 6, 1-14

Abstract: Ascaridiosis in poultry results in a reduction in body weight gain, egg production, as well as microelement levels. Infected poultry have higher demands on feed with the addition of essential elements including zinc. The effects of the infection by Ascaridia galli and the supplementation of inorganic zinc on the immune status of broilers were monitored through evaluation of the relative expression of selected genes (interleukins, IFN-γ, and TNF-α) by real-time PCR, haematology parameters by microscopy, and quantitative changes of lamina propria lymphocytes by flow cytometry in day 7 and day 14 of the study. We observed that the enrichment of the diet with inorganic zinc has a positive effect on the relative percentage of CD4+ lamina propria lymphocytes in the jejunum and on heterophil counts in blood. In addition, it was concluded that inorganic zinc has an anti-inflammatory effect (downregulation of TNF-α and IL-17) and activates IgA-producing cells in the jejunum of chicks infected with A. galli .

Keywords: zinc; imunity; Ascaridia galli; chicken (search for similar items in EconPapers)
JEL-codes: Q1 Q10 Q11 Q12 Q13 Q14 Q15 Q16 Q17 Q18 (search for similar items in EconPapers)
Date: 2021
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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