Effect of Maternal Dietary Condensed Tannins from Sainfoin ( Onobrychis viciifolia ) on Gut Health and Antioxidant-Immune Crosstalk in Suckling Lambs

Jonathan Pelegrin-Valls, Javier Álvarez-Rodríguez, María José Martín-Alonso, Gustavo Adolfo Ramírez, Claudia Baila, Sandra Lobon, Margalida Joy and Beatriz Serrano-Pérez
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Jonathan Pelegrin-Valls: Departament de Ciència Animal, Universitat de Lleida, Av. Alcalde Rovira Roure 191, 25198 Lleida, Spain
Javier Álvarez-Rodríguez: Departament de Ciència Animal, Universitat de Lleida, Av. Alcalde Rovira Roure 191, 25198 Lleida, Spain
María José Martín-Alonso: Departament de Ciència Animal, Universitat de Lleida, Av. Alcalde Rovira Roure 191, 25198 Lleida, Spain
Gustavo Adolfo Ramírez: Departament de Ciència Animal, Universitat de Lleida, Av. Alcalde Rovira Roure 191, 25198 Lleida, Spain
Claudia Baila: Centro de Investigación y Tecnología Agroalimentaria de Aragón, Av. Montaña 930, 50059 Zaragoza, Spain
Sandra Lobon: Centro de Investigación y Tecnología Agroalimentaria de Aragón, Av. Montaña 930, 50059 Zaragoza, Spain
Margalida Joy: Centro de Investigación y Tecnología Agroalimentaria de Aragón, Av. Montaña 930, 50059 Zaragoza, Spain
Beatriz Serrano-Pérez: Departament de Ciència Animal, Universitat de Lleida, Av. Alcalde Rovira Roure 191, 25198 Lleida, Spain

Agriculture, 2022, vol. 12, issue 10, 1-13

Abstract: Ewes fed sainfoin (a source of condensed tannins “CT”) may influence the homeostasis of the gastrointestinal tract of suckling lambs. This study investigated the effects of CT from sainfoin in the maternal diet on plasma fructosamine, faecal coccidian excretion, and gene expression of immune and antioxidant markers in jejunum and ileum of suckling lambs. Twelve Rasa Aragonesa lambs with their dams were selected. The maternal diet was based on fresh sainfoin (SAINFOIN, n = 6) and sainfoin + polyethylene-glycol (SAINFOIN + PEG, as a CT-binder, n = 6) plus a daily supplement of 200 g barley in both groups. A lower percentage of lambs that shed more than 10 oocysts/g faeces was observed in SAINFOIN compared to the SAINFOIN + PEG group ( p = 0.07). Jejunal gene expression of transforming growth factor-β1, tumour necrosis factor-α, and glutathione peroxidase ( GPX ) 1 and 4 were lower in the SAINFOIN group ( p < 0.05). In contrast, ileal catalase and GPX2 expression were increased in the SAINFOIN group ( p < 0.05). Overall, the results suggest that the presence of CT in the dams’ diets has a positive effect on reducing excreted coccidian oocysts and favours antioxidant-immune crosstalk at gut level in suckling lambs.

Keywords: suckling lambs; sainfoin; condensed tannins; immune response; oxidative stress; coccidiosis (search for similar items in EconPapers)
JEL-codes: Q1 Q10 Q11 Q12 Q13 Q14 Q15 Q16 Q17 Q18 (search for similar items in EconPapers)
Date: 2022
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