Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano Era

Kun Wang, Qinyue Lu, Xiang Cao, Yuhao Wang, Yanni Wu, Zhi Chen and Zhangping Yang ()
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Kun Wang: College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
Qinyue Lu: College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
Xiang Cao: College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
Yuhao Wang: College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
Yanni Wu: College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
Zhi Chen: College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
Zhangping Yang: College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China

Agriculture, 2022, vol. 12, issue 12, 1-21

Abstract: Like other pentacyclic triterpenoids, oleanolic acid, a natural plant metabolite prevalent in plant peels, stems, and leaves, is regarded as a possible drug candidate. A growing number of studies have shown that oleanolic acid exhibits a variety of beneficial properties, including antiviral, anti-inflammatory, antioxidant, anticancer, and hepatoprotective effects. Additionally, the rapid advance of nanotechnology has dramatically improved oleanolic acid’s bioavailability and minimized its disadvantages, leading to unexpected changes in its pharmacological activity and use. Therefore, our aim was to review the progress of research on the distribution and biological properties of oleanolic acid in plants and to discuss new pharmaceutical approaches for oleanolic acid.

Keywords: oleanolic acid; nano; nanoparticles; anti-inflammatory; antitumor (search for similar items in EconPapers)
JEL-codes: Q1 Q10 Q11 Q12 Q13 Q14 Q15 Q16 Q17 Q18 (search for similar items in EconPapers)
Date: 2022
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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