Nicotine Dependence in Patients with Major Depressive Disorder and Psychotic Disorders and Its Relationship with Quality of Life

Peizhi Wang, Edimansyah Abdin, P.V. Asharani, Vanessa Seet, Fiona Devi, Kumarasan Roystonn, Ying Ying Lee, Laxman Cetty, Wen Lin Teh, Swapna Verma, Yee Ming Mok and Mythily Subramaniam
Additional contact information
Peizhi Wang: Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Bunagkok View, Singapore 539747, Singapore
P.V. Asharani: Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Bunagkok View, Singapore 539747, Singapore
Vanessa Seet: Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Bunagkok View, Singapore 539747, Singapore
Fiona Devi: Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Bunagkok View, Singapore 539747, Singapore
Kumarasan Roystonn: Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Bunagkok View, Singapore 539747, Singapore
Ying Ying Lee: Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Bunagkok View, Singapore 539747, Singapore
Laxman Cetty: Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Bunagkok View, Singapore 539747, Singapore
Wen Lin Teh: Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Bunagkok View, Singapore 539747, Singapore
Swapna Verma: Early Psychosis Intervention Programme, Institute of Mental Health, Singapore 539747, Singapore
Yee Ming Mok: Department of Mood and Anxiety, Institute of Mental Health, Buangkok Green Medical Park, 10 Buangkok View, Singapore 539747, Singapore
Mythily Subramaniam: Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Bunagkok View, Singapore 539747, Singapore

IJERPH, 2021, vol. 18, issue 24, 1-12

Abstract: The aim of the current study was to examine the associations between nicotine dependence and quality of life (QOL) among individuals diagnosed with major depressive disorder (MDD) or psychotic disorders. Methods: A total of 378 participants diagnosed with either MDD or psychotic disorders were recruited. The Fagerstorm Test for Nicotine Dependence was used to measure the level of nicotine dependence. The SF-12 health survey questionnaire was used to measure the QOL. Results: The prevalence of nicotine dependence was 23.3% in this sample population. For those diagnosed with MDD, moderate level of nicotine dependence was negatively associated with Vitality and Mental Component Score. For those diagnosed with a psychotic disorder high nicotine dependence was negatively associated with Role Emotional, Mental Health and Mental Component Score. Discussion: Compared to the general population, the prevalence of smoking in this psychiatric population was 2.4 times higher, while that of nicotine dependence was seven times higher. Individuals with psychotic disorder generally reported better QOL as compared to individuals with MDD. QOL differed across diagnostic groups with regards to socio-demographics, such as age, ethnicity, marital status, education, employment status and monthly income. Among individuals with MDD and psychotic disorders, different levels of nicotine dependence resulted in different levels of association with QOL. More research is needed to better understand the differences in QOL among the varying levels of nicotine dependence.

Keywords: nicotine dependence; quality of life; major depressive disorder; psychotic disorder (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2021
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