MSD: Continuous Pharmaceutical Manufacturing Data for the 2024 MSOM Data-Driven Research Challenge

Tugce Martagan (), Marc Baaijens (), Coen Dirckx (), James Holman (), Robert Meyer (), Oscar Repping () and Bram van Ravenstein ()
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Tugce Martagan: Department of Industrial Engineering and Innovation Sciences, Eindhoven University of Technology, 5612 AZ Eindhoven, Netherlands
Marc Baaijens: Ceva Santé Animale, 33500 Libourne, France
Coen Dirckx: Department of Industrial Engineering and Innovation Sciences, Eindhoven University of Technology, 5612 AZ Eindhoven, Netherlands; MSD, 5831 AN Boxmeer, Netherlands
James Holman: Technology Management, GEA Group, Eastleigh SO53 4DG, United Kingdom
Robert Meyer: Merck & Co., Inc., Rahway, New Jersey 07065
Oscar Repping: Ceva Santé Animale, 33500 Libourne, France
Bram van Ravenstein: MSD, 5831 AN Boxmeer, Netherlands

Manufacturing & Service Operations Management, 2024, vol. 26, issue 5, 1587-1604

Abstract: To support the 2024 MSOM Data-Driven Research Challenge, Merck & Co., Inc., Rahway, New Jersey (hereafter “MSD”), provides pharmaceutical manufacturing data from a continuous tablet production setting. The data set contains approximately 300 million data points related to around 75 process parameters monitored over 120 hours. In this paper, we present the data set and share our vision to inspire and facilitate new applications of operations management (OM) methodologies in pharmaceutical manufacturing. We begin with an introduction to pharmaceutical manufacturing for OM researchers and then elaborate on emerging technologies, common industry challenges, and research opportunities. We explain the data set and propose a roadmap for future research directions. Researchers are welcome to examine the proposed research questions or analyze other research questions using the data set. Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2024.0860

Keywords: OM practice; data challenge; pharmaceutical industry; biomanufacturing (search for similar items in EconPapers)
Date: 2024
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