Functional rafts in cell membranes

Kai Simons and Elina Ikonen
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Kai Simons: European Molecular Biology Laboratory, Cell Biology Programme
Elina Ikonen: National Public Health Institute

Nature, 1997, vol. 387, issue 6633, 569-572

Abstract: Abstract A new aspect of cell membrane structure is presented, based on the dynamic clustering of sphingolipids and cholesterol to form rafts that move within the fluid bilayer. It is proposed that these rafts function as platforms for the attachment of proteins when membranes are moved around inside the cell and during signal transduction.

Date: 1997
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DOI: 10.1038/42408

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