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2025, volume 642, articles 8068

Peter Lax obituary: mathematician who pioneered computer-based solutions to real-world problems pp. 568-568

Jeremy Berg

2025, volume 642, articles 8067

Author Correction: A human brain map of mitochondrial respiratory capacity and diversity pp. E12-E12

Eugene V. Mosharov, Ayelet M. Rosenberg, Anna S. Monzel, Corey A. Osto, Linsey Stiles, Gorazd B. Rosoklija, Andrew J. Dwork, Snehal Bindra, Alex Junker, Ya Zhang, Masashi Fujita, Madeline B. Mariani, Mihran Bakalian, David Sulzer, Philip L. Jager, Vilas Menon, Orian S. Shirihai, J. John Mann, Mark D. Underwood, Maura Boldrini, Michel Thiebaut de Schotten and Martin Picard

Author Correction: Global methane emissions from rivers and streams pp. E13-E13

Gerard Rocher-Ros, Emily H. Stanley, Luke C. Loken, Nora J. Casson, Peter A. Raymond, Shaoda Liu, Giuseppe Amatulli and Ryan A. Sponseller

Author Correction: Structure and topography of the synaptic V-ATPase–synaptophysin complex pp. E14-E14

Chuchu Wang, Wenhong Jiang, Jeremy Leitz, Kailu Yang, Luis Esquivies, Xing Wang, Xiaotao Shen, Richard G. Held, Daniel J. Adams, Tamara Basta, Lucas Hampton, Ruiqi Jian, Lihua Jiang, Michael H. B. Stowell, Wolfgang Baumeister, Qiang Guo and Axel T. Brunger

Author Correction: Chromosome end protection by RAP1-mediated inhibition of DNA-PK pp. E15-E15

Patrik Eickhoff, Ceylan Sonmez, Charlotte E. L. Fisher, Oviya Inian, Theodoros I. Roumeliotis, Angela dello Stritto, Jörg Mansfeld, Jyoti S. Choudhary, Sebastian Guettler, Francisca Lottersberger and Max E. Douglas

Publisher Correction: Multi-zonal liver organoids from human pluripotent stem cells pp. E16-E16

Hasan Al Reza, Connie Santangelo, Kentaro Iwasawa, Abid Al Reza, Sachiko Sekiya, Kathryn Glaser, Alexander Bondoc, Jonathan Merola and Takanori Takebe

Publisher Correction: Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis pp. E17-E17

Xueqian Zhuang, Qing Wang, Simon Joost, Alexander Ferrena, David T. Humphreys, Zhuxuan Li, Melissa Blum, Klavdija Krause, Selena Ding, Yuna Landais, Yingqian Zhan, Yang Zhao, Ronan Chaligne, Joo-Hyeon Lee, Sebastian E. Carrasco, Umeshkumar K. Bhanot, Richard P. Koche, Matthew J. Bott, Pekka Katajisto, Yadira M. Soto-Feliciano, Thomas Pisanic, Tiffany Thomas, Deyou Zheng, Emily S. Wong and Tuomas Tammela

Publisher Correction: Imaging surface structure and premelting of ice Ih with atomic resolution pp. E18-E18

Jiani Hong, Ye Tian, Tiancheng Liang, Xinmeng Liu, Yizhi Song, Dong Guan, Zixiang Yan, Jiadong Guo, Binze Tang, Duanyun Cao, Jing Guo, Ji Chen, Ding Pan, Li-Mei Xu, En-Ge Wang and Ying Jiang

Dementia is deadly — the UN needs to take it more seriously pp. 273-273

Paola Barbarino

To progress, science must be truly global pp. 274-274

Marcelo Knobel

‘You’re just not welcome’: researchers grapple with US plan to revoke Chinese student visas pp. 277-278

Natasha Gilbert

Rare ‘ambidextrous’ protein breaks rules of handedness pp. 278-279

Ewen Callaway

NIH grant cuts will axe clinical trials abroad — and could leave thousands without care pp. 279-280

Max Kozlov

Brain-reading devices raise ethical dilemmas — researchers propose protections pp. 280-281

Kristel Tjandra

Web-scraping AI bots cause disruption for scientific databases and journals pp. 281-282

Diana Kwon

‘Scienticide’ in Argentina sparks huge protest by researchers pp. 282-283

Martín De Ambrosio and Fermín Koop

Genomics pioneer fired from firm he founded: ‘It was not easy to domesticate me’ pp. 284-284

Ewen Callaway

How to keep weight off after obesity drugs pp. 286-288

Elie Dolgin

How to speak to a vaccine sceptic: research reveals what works pp. 289-291

Helen Pearson

How DEI is misunderstood — and the real route to gender equality pp. 292-294

Pragya Agarwal

Do our observations make reality happen? pp. 294-297

Alyssa Ney

What puzzles people, past and present: Books in brief pp. 297-297

Andrew Robinson

Yvonne Choquet-Bruhat obituary: mathematician who established that Einstein’s equations mirror the real world pp. 298-298

Mihalis Dafermos

A message from island leaders: protect the Pacific Ocean from deep-sea mining pp. 299-302

Moetai Brotherson and Surangel Whipps

Reduced investment in universities has multifaceted effects pp. 303-303

Akiko Hashiguchi

Not all clinical data in the United States are fragmented pp. 303-303

Enlli Lewis

Greening nickel extraction requires institutional and financial support pp. 303-303

Zhangxin Frank Liu

Making concrete sustainable globally requires technology transfer pp. 303-303

Chengqian Wen, Xintao Xu and Huiping Guo

Digitally constructed mask brings a damaged painting back to life pp. 305-306

Hartmut Kutzke

Brain tissue artificially expanded to show how neurons wire together pp. 306-307

Joergen M. R. Kornfeld

Simulation of matter–antimatter creation on quantum platforms pp. 308-309

Michele Burrello

Age-related blood condition counteracted with a common diabetes drug pp. 309-311

Elmira Khabusheva and Margaret A. Goodell

Lipid-degrading small molecule kills cancer cells by ferroptosis pp. 311-312

Mike Lange and James A. Olzmann

Computer processors built from 2D materials pp. 312-313

Michael Waltl and Tibor Grasser

Visualizing dynamics of charges and strings in (2 + 1)D lattice gauge theories pp. 315-320

T. A. Cochran, B. Jobst, E. Rosenberg, Y. D. Lensky, G. Gyawali, N. Eassa, M. Will, A. Szasz, D. Abanin, R. Acharya, L. Aghababaie Beni, T. I. Andersen, M. Ansmann, F. Arute, K. Arya, A. Asfaw, J. Atalaya, R. Babbush, B. Ballard, J. C. Bardin, A. Bengtsson, A. Bilmes, A. Bourassa, J. Bovaird, M. Broughton, D. A. Browne, B. Buchea, B. B. Buckley, T. Burger, B. Burkett, N. Bushnell, A. Cabrera, J. Campero, H.-S. Chang, Z. Chen, B. Chiaro, J. Claes, A. Y. Cleland, J. Cogan, R. Collins, P. Conner, W. Courtney, A. L. Crook, B. Curtin, S. Das, S. Demura, L. Lorenzo, A. Paolo, P. Donohoe, I. Drozdov, A. Dunsworth, A. Eickbusch, A. Moshe Elbag, M. Elzouka, C. Erickson, V. S. Ferreira, L. Flores Burgos, E. Forati, A. G. Fowler, B. Foxen, S. Ganjam, R. Gasca, É. Genois, W. Giang, D. Gilboa, R. Gosula, A. Grajales Dau, D. Graumann, A. Greene, J. A. Gross, S. Habegger, M. Hansen, M. P. Harrigan, S. D. Harrington, P. Heu, O. Higgott, J. Hilton, H.-Y. Huang, A. Huff, W. Huggins, E. Jeffrey, Z. Jiang, C. Jones, C. Joshi, P. Juhas, D. Kafri, H. Kang, A. H. Karamlou, K. Kechedzhi, T. Khaire, T. Khattar, M. Khezri, S. Kim, P. Klimov, B. Kobrin, A. Korotkov, F. Kostritsa, J. Kreikebaum, V. Kurilovich, D. Landhuis, T. Lange-Dei, B. Langley, K.-M. Lau, J. Ledford, K. Lee, B. Lester, L. Guevel, W. Li, A. T. Lill, W. Livingston, A. Locharla, D. Lundahl, A. Lunt, S. Madhuk, A. Maloney, S. Mandrà, L. Martin, O. Martin, C. Maxfield, J. McClean, M. McEwen, S. Meeks, A. Megrant, K. Miao, R. Molavi, S. Molina, S. Montazeri, R. Movassagh, C. Neill, M. Newman, A. Nguyen, M. Nguyen, C.-H. Ni, K. Ottosson, A. Pizzuto, R. Potter, O. Pritchard, C. Quintana, G. Ramachandran, M. Reagor, D. Rhodes, G. Roberts, K. Sankaragomathi, K. Satzinger, H. Schurkus, M. Shearn, A. Shorter, N. Shutty, V. Shvarts, V. Sivak, S. Small, W. C. Smith, S. Springer, G. Sterling, J. Suchard, A. Sztein, D. Thor, M. Torunbalci, A. Vaishnav, J. Vargas, S. Vdovichev, G. Vidal, C. Vollgraff Heidweiller, S. Waltman, S. X. Wang, B. Ware, T. White, K. Wong, B. W. K. Woo, C. Xing, Z. Jamie Yao, P. Yeh, B. Ying, J. Yoo, N. Yosri, G. Young, A. Zalcman, Y. Zhang, N. Zhu, N. Zobrist, S. Boixo, J. Kelly, E. Lucero, Y. Chen, V. Smelyanskiy, H. Neven, A. Gammon-Smith, F. Pollmann, M. Knap and P. Roushan

Observation of string breaking on a (2 + 1)D Rydberg quantum simulator pp. 321-326

Daniel González-Cuadra, Majd Hamdan, Torsten V. Zache, Boris Braverman, Milan Kornjača, Alexander Lukin, Sergio H. Cantú, Fangli Liu, Sheng-Tao Wang, Alexander Keesling, Mikhail D. Lukin, Peter Zoller and Alexei Bylinskii

A complementary two-dimensional material-based one instruction set computer pp. 327-335

Subir Ghosh, Yikai Zheng, Musaib Rafiq, Harikrishnan Ravichandran, Yongwen Sun, Chen Chen, Mrinmoy Goswami, Najam U Sakib, Muhtasim Ul Karim Sadaf, Andrew Pannone, Samriddha Ray, Joan M. Redwing, Yang Yang, Shubham Sahay and Saptarshi Das

Milli-spinner thrombectomy pp. 336-342

Yilong Chang, Shuai Wu, Qi Li, Benjamin Pulli, Darren Salmi, Paul Yock, Jeremy J. Heit and Ruike Renee Zhao

Physical restoration of a painting with a digitally constructed mask pp. 343-350

Alex Kachkine

The structure of liquid carbon elucidated by in situ X-ray diffraction pp. 351-355

D. Kraus, J. Rips, M. Schörner, M. G. Stevenson, J. Vorberger, D. Ranjan, J. Lütgert, B. Heuser, J. H. Eggert, H.-P. Liermann, I. I. Oleynik, S. Pandolfi, R. Redmer, A. Sollier, C. Strohm, T. J. Volz, B. Albertazzi, S. J. Ali, L. Antonelli, C. Bähtz, O. B. Ball, S. Banerjee, A. B. Belonoshko, C. A. Bolme, V. Bouffetier, R. Briggs, K. Buakor, T. Butcher, V. Cerantola, J. Chantel, A. L. Coleman, J. Collier, G. W. Collins, A. J. Comley, T. E. Cowan, G. Cristoforetti, H. Cynn, A. Descamps, A. Cicco, S. Dio Cafiso, F. Dorchies, M. J. Duff, A. Dwivedi, C. Edwards, D. Errandonea, S. Galitskiy, E. Galtier, H. Ginestet, L. Gizzi, A. Gleason, S. Göde, J. M. Gonzalez, M. G. Gorman, M. Harmand, N. J. Hartley, P. G. Heighway, C. Hernandez-Gomez, A. Higginbotham, H. Höppner, R. J. Husband, T. M. Hutchinson, H. Hwang, D. A. Keen, J. Kim, P. Koester, Z. Konôpková, A. Krygier, L. Labate, A. Laso Garcia, A. E. Lazicki, Y. Lee, P. Mason, M. Masruri, B. Massani, E. E. McBride, J. D. McHardy, D. McGonegle, C. McGuire, R. S. McWilliams, S. Merkel, G. Morard, B. Nagler, M. Nakatsutsumi, K. Nguyen-Cong, A.-M. Norton, N. Ozaki, C. Otzen, D. J. Peake, A. Pelka, K. A. Pereira, J. P. Phillips, C. Prescher, T. R. Preston, L. Randolph, A. Ravasio, D. Santamaria-Perez, D. J. Savage, M. Schölmerich, J.-P. Schwinkendorf, S. Singh, J. Smith, R. F. Smith, J. Spear, C. Spindloe, T.-A. Suer, M. Tang, M. Toncian, T. Toncian, S. J. Tracy, A. Trapananti, C. E. Vennari, T. Vinci, M. Tyldesley, S. C. Vogel, J. P. S. Walsh, J. S. Wark, J. T. Willman, L. Wollenweber, U. Zastrau, E. Brambrink, K. Appel and M. I. McMahon

Preparation of a neutral nitrogen allotrope hexanitrogen C2h-N6 pp. 356-360

Weiyu Qian, Artur Mardyukov and Peter R. Schreiner

Global dominance of seasonality in shaping lake-surface-extent dynamics pp. 361-368

Luoqi Li, Di Long, Yiming Wang and R. Iestyn Woolway

Air pollution modulates trends and variability of the global methane budget pp. 369-375

Yuanhong Zhao, Bo Zheng, Marielle Saunois, Philippe Ciais, Michaela I. Hegglin, Shengmin Lu, Yifan Li and Philippe Bousquet

Ru and W isotope systematics in ocean island basalts reveals core leakage pp. 376-380

Nils Messling, Matthias Willbold, Leander Kallas, Tim Elliott, J. Godfrey Fitton, Thomas Müller and Dennis Geist

A cryptic role for reciprocal helping in a cooperatively breeding bird pp. 381-388

Alexis D. Earl, Gerald G. Carter, Arden G. Berlinger, Elkana Korir, Shailee S. Shah, Wilson N. Watetu and Dustin R. Rubenstein

The phased pan-genome of tetraploid European potato pp. 389-397

Hequan Sun, Sergio Tusso, Craig I. Dent, Manish Goel, Raúl Y. Wijfjes, Lisa C. Baus, Xiao Dong, José A. Campoy, Ana Kurdadze, Birgit Walkemeier, Christine Sänger, Bruno Huettel, Ronald C. B. Hutten, Herman J. van Eck, Klaus J. Dehmer and Korbinian Schneeberger

Light-microscopy-based connectomic reconstruction of mammalian brain tissue pp. 398-410

Mojtaba R. Tavakoli, Julia Lyudchik, Michał Januszewski, Vitali Vistunou, Nathalie Agudelo Dueñas, Jakob Vorlaufer, Christoph Sommer, Caroline Kreuzinger, Bárbara Oliveira, Alban Cenameri, Gaia Novarino, Viren Jain and Johann G. Danzl

Psilocybin’s lasting action requires pyramidal cell types and 5-HT2A receptors pp. 411-420

Ling-Xiao Shao, Clara Liao, Pasha A. Davoudian, Neil K. Savalia, Quan Jiang, Cassandra Wojtasiewicz, Diran Tan, Jack D. Nothnagel, Rong-Jian Liu, Samuel C. Woodburn, Olesia M. Bilash, Hail Kim, Alicia Che and Alex C. Kwan

Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs pp. 421-430

Mohsen Hosseini, Veronique Voisin, Ali Chegini, Angelica Varesi, Severine Cathelin, Dhanoop Manikoth Ayyathan, Alex C. H. Liu, Yitong Yang, Vivian Wang, Abdula Maher, Eric Grignano, Julie A. Reisz, Angelo D’Alessandro, Kira Young, Yiyan Wu, Martina Fiumara, Samuele Ferrari, Luigi Naldini, Federico Gaiti, Shraddha Pai, Grace Egan, Aaron D. Schimmer, Gary D. Bader, John E. Dick, Stephanie Z. Xie, Jennifer J. Trowbridge and Steven M. Chan

Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis pp. 431-441

Malgorzata Gozdecka, Monika Dudek, Sean Wen, Muxin Gu, Richard J. Stopforth, Justyna Rak, Aristi Damaskou, Guinevere L. Grice, Matthew A. McLoughlin, Laura Bond, Rachael Wilson, George Giotopoulos, Vijaya Mahalingam Shanmugiah, Rula Bany Bakar, Eliza Yankova, Jonathan L. Cooper, Nisha Narayan, Sarah J. Horton, Ryan Asby, Dean C. Pask, Annalisa Mupo, Graham Duddy, Ludovica Marando, Theodoros Georgomanolis, Paul Carter, Amirtha Priya Ramesh, William G. Dunn, Clea Barcena, Paolo Gallipoli, Kosuke Yusa, Slavé Petrovski, Penny Wright, Pedro M. Quiros, Christian Frezza, James A. Nathan, Arthur Kaser, Siddhartha Kar, Konstantinos Tzelepis, Jonathan Mitchell, Margarete A. Fabre, Brian J. P. Huntly and George S. Vassiliou

Towards conversational diagnostic artificial intelligence pp. 442-450

Tao Tu, Mike Schaekermann, Anil Palepu, Khaled Saab, Jan Freyberg, Ryutaro Tanno, Amy Wang, Brenna Li, Mohamed Amin, Yong Cheng, Elahe Vedadi, Nenad Tomasev, Shekoofeh Azizi, Karan Singhal, Le Hou, Albert Webson, Kavita Kulkarni, S. Sara Mahdavi, Christopher Semturs, Juraj Gottweis, Joelle Barral, Katherine Chou, Greg S. Corrado, Yossi Matias, Alan Karthikesalingam and Vivek Natarajan

Towards accurate differential diagnosis with large language models pp. 451-457

Daniel McDuff, Mike Schaekermann, Tao Tu, Anil Palepu, Amy Wang, Jake Garrison, Karan Singhal, Yash Sharma, Shekoofeh Azizi, Kavita Kulkarni, Le Hou, Yong Cheng, Yun Liu, S. Sara Mahdavi, Sushant Prakash, Anupam Pathak, Christopher Semturs, Shwetak Patel, Dale R. Webster, Ewa Dominowska, Juraj Gottweis, Joelle Barral, Katherine Chou, Greg S. Corrado, Yossi Matias, Jake Sunshine, Alan Karthikesalingam and Vivek Natarajan

Global evolution of inflammatory bowel disease across epidemiologic stages pp. 458-466

Lindsay Hracs, Joseph W. Windsor, Julia Gorospe, Michael Cummings, Stephanie Coward, Michael J. Buie, Joshua Quan, Quinn Goddard, Léa Caplan, Ante Markovinović, Tyler Williamson, Yvonne Abbey, Murdani Abdullah, Maria T. Abreu, Vineet Ahuja, Raja Affendi Raja Ali, Mansour Altuwaijri, Domingo Balderramo, Rupa Banerjee, Eric I. Benchimol, Charles N. Bernstein, Eduard Brunet-Mas, Johan Burisch, Vui Heng Chong, Iris Dotan, Usha Dutta, Sara El Ouali, Angela Forbes, Anders Forss, Richard Gearry, Viet Hang Dao, Juanda Leo Hartono, Ida Hilmi, Phoebe Hodges, Gareth-Rhys Jones, Fabián Juliao-Baños, Jamilya Kaibullayeva, Paul Kelly, Taku Kobayashi, Paulo Gustavo Kotze, Peter L. Lakatos, Charlie W. Lees, Julajak Limsrivilai, Bobby Lo, Edward V. Loftus, Jonas F. Ludvigsson, Joyce W. Y. Mak, YingLei Miao, Ka Kei Ng, Shinji Okabayashi, Ola Olén, Remo Panaccione, Mukesh Sharma Paudel, Abel Botelho Quaresma, David T. Rubin, Marcellus Simadibrata, Yang Sun, Hidekazu Suzuki, Martin Toro, Dan Turner, Beatriz Iade, Shu Chen Wei, Jesus K. Yamamoto-Furusho, Suk-Kyun Yang, Siew C. Ng and Gilaad G. Kaplan

TIR domains produce histidine-ADPR as an immune signal in bacteria pp. 467-473

Dziugas Sabonis, Carmel Avraham, Renee B. Chang, Allen Lu, Ehud Herbst, Arunas Silanskas, Deividas Vilutis, Azita Leavitt, Erez Yirmiya, Hunter C. Toyoda, Audrone Ruksenaite, Mindaugas Zaremba, Ilya Osterman, Gil Amitai, Philip J. Kranzusch, Rotem Sorek and Giedre Tamulaitiene

PLA2G15 is a BMP hydrolase and its targeting ameliorates lysosomal disease pp. 474-483

Kwamina Nyame, Jian Xiong, Hisham N. Alsohybe, Arthur P. H. Jong, Isabelle V. Peña, Ricardo Miguel, Thijn R. Brummelkamp, Guido Hartmann, Sebastian M. B. Nijman, Matthijs Raaben, Judith A. Simcox, Vincent A. Blomen and Monther Abu-Remaileh

Deep Visual Proteomics maps proteotoxicity in a genetic liver disease pp. 484-491

Florian A. Rosenberger, Sophia C. Mädler, Katrine Holtz Thorhauge, Sophia Steigerwald, Malin Fromme, Mikhail Lebedev, Caroline A. M. Weiss, Marc Oeller, Maria Wahle, Andreas Metousis, Maximilian Zwiebel, Niklas A. Schmacke, Sönke Detlefsen, Peter Boor, Ondřej Fabián, Soňa Fraňková, Aleksander Krag, Pavel Strnad and Matthias Mann

Activation of lysosomal iron triggers ferroptosis in cancer pp. 492-500

Tatiana Cañeque, Leeroy Baron, Sebastian Müller, Alanis Carmona, Ludovic Colombeau, Antoine Versini, Stéphanie Solier, Christine Gaillet, Fabien Sindikubwabo, Julio L. Sampaio, Marie Sabatier, Eikan Mishima, Armel Picard-Bernes, Laurène Syx, Nicolas Servant, Bérangère Lombard, Damarys Loew, Jiashuo Zheng, Bettina Proneth, Leishemba K. Thoidingjam, Laurence Grimaud, Cameron S. Fraser, Krystina J. Szylo, Emma Kazarian, Caroline Bonnet, Emmanuelle Charafe-Jauffret, Christophe Ginestier, Patricia Santofimia-Castaño, Matias Estaras, Nelson Dusetti, Juan Lucio Iovanna, Antonio Sa Cunha, Gabriella Pittau, Pascal Hammel, Dimitri Tzanis, Sylvie Bonvalot, Sarah Watson, Vincent Gandon, Aditya Upadhyay, Derek A. Pratt, Florêncio Porto Freitas, José Pedro Friedmann Angeli, Brent R. Stockwell, Marcus Conrad, Jessalyn M. Ubellacker and Raphaël Rodriguez

Small molecules restore mutant mitochondrial DNA polymerase activity pp. 501-507

Sebastian Valenzuela, Xuefeng Zhu, Bertil Macao, Mattias Stamgren, Carol Geukens, Paul S. Charifson, Gunther Kern, Emily Hoberg, Louise Jenninger, Anja V. Gruszczyk, Seoeun Lee, Katarina A. S. Johansson, Javier Miralles Fusté, Yonghong Shi, S. Jordan Kerns, Laleh Arabanian, Gabriel Martinez Botella, Sofie Ekström, Jeremy Green, Andrew M. Griffin, Carlos Pardo-Hernández, Thomas A. Keating, Barbara Küppers-Munther, Nils-Göran Larsson, Cindy Phan, Viktor Posse, Juli E. Jones, Xie Xie, Simon Giroux, Claes M. Gustafsson and Maria Falkenberg

Perturbing LSD1 and WNT rewires transcription to synergistically induce AML differentiation pp. 508-518

Amir Hosseini, Abhinav Dhall, Nemo Ikonen, Natalia Sikora, Sylvain Nguyen, Yuqi Shen, Maria Luisa Jurgensen Amaral, Alan Jiao, Felice Wallner, Philipp Sergeev, Yuhua Lim, Yuanqin Yang, Binje Vick, Kimihito Cojin Kawabata, Ari Melnick, Paresh Vyas, Bing Ren, Irmela Jeremias, Bethan Psaila, Caroline A. Heckman, M. Andrés Blanco and Yang Shi

Swinging lever mechanism of myosin directly shown by time-resolved cryo-EM pp. 519-526

David P. Klebl, Sean N. McMillan, Cristina Risi, Eva Forgacs, Betty Virok, Jennifer L. Atherton, Sarah A. Harris, Michele Stofella, Donald A. Winkelmann, Frank Sobott, Vitold E. Galkin, Peter J. Knight, Stephen P. Muench, Charlotte A. Scarff and Howard D. White

Want to enhance lab safety? Try a little role playing first pp. 527-529

Myriam Vidal Valero

Meet the engineer using deep learning to restore Renaissance art pp. 530-532

Amanda Heidt

Making slabs and sleepers from old appliances pp. 534-534

Patricia Maia Noronha

2025, volume 642, articles 8066

False positives in study of memory-related gene expression pp. E1-E3

Eran A. Mukamel and Zhaoxia Yu

Reply to: False positives in study of memory-related gene expression pp. E4-E6

Wenfei Sun, Zhihui Liu, Xian Jiang, Michelle B. Chen, Hua Dong, Jonathan Liu, Thomas C. Südhof and Stephen R. Quake

Dynamic range and precision of hybrid vision sensors pp. E7-E8

Minhao Yang, Rodney Douglas, Chenghan Li, Andreas Suess, Hyunsurk Ryu, Christoph Posch, Shoushun Chen, Raphael Berner, Tetsuya Yagi, Boyd Fowler and Tobi Delbruck

Disaster relief needs community trust — authorities must earn it pp. 9-9

Maryam Rokhideh

Author Correction: Inhibitory specificity from a connectomic census of mouse visual cortex pp. E9-E9

Casey M. Schneider-Mizell, Agnes L. Bodor, Derrick Brittain, JoAnn Buchanan, Daniel J. Bumbarger, Leila Elabbady, Clare Gamlin, Daniel Kapner, Sam Kinn, Gayathri Mahalingam, Sharmishtaa Seshamani, Shelby Suckow, Marc Takeno, Russel Torres, Wenjing Yin, Sven Dorkenwald, J. Alexander Bae, Manuel A. Castro, Akhilesh Halageri, Zhen Jia, Chris Jordan, Nico Kemnitz, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Eric Mitchell, Shanka Subhra Mondal, Shang Mu, Barak Nehoran, Sergiy Popovych, William Silversmith, Nicholas L. Turner, William Wong, Jingpeng Wu, Jacob Reimer, Andreas S. Tolias, H. Sebastian Seung, R. Clay Reid, Forrest Collman and Nuno Maçarico Costa

Author Correction: Soft–hard zwitterionic additives for aqueous halide flow batteries pp. E10-E10

Gyohun Choi, Patrick Sullivan, Xiu-Liang Lv, Wenjie Li, Kwanpyung Lee, Haoyu Kong, Sam Gessler, J. R. Schmidt and Dawei Feng

How I’m bringing the voices of local fishers into ocean policies pp. 10-10

Gaoussou Gueye

Author Correction: Earth’s ambipolar electrostatic field and its role in ion escape to space pp. E11-E11

Glyn A. Collinson, Alex Glocer, Robert Pfaff, Aroh Barjatya, Rachel Conway, Aaron Breneman, James Clemmons, Francis Eparvier, Robert Michell, David Mitchell, Suzie Imber, Hassanali Akbari, Lance Davis, Andrew Kavanagh, Ellen Robertson, Diana Swanson, Shaosui Xu, Jacob Miller, Timothy Cameron, Dennis Chornay, Paulo Uribe, Long Nguyen, Robert Clayton, Nathan Graves, Shantanab Debchoudhury, Henry Valentine and Ahmed Ghalib

Trump’s call for ‘gold-standard science’ has prompted an outcry: here’s why pp. 13-14

Jeff Tollefson and Dan Garisto

Harvard researchers devastated as Trump team cuts nearly 1,000 grants pp. 15-16

Dan Garisto

Scientific conferences are leaving the US amid border fears pp. 16-17

Miryam Naddaf

These contact lenses give people infrared vision — even with their eyes shut pp. 17-18

Elizabeth Gibney

How the brain spies on the gut: with help from newfound immune cells pp. 18-19

Gemma Conroy

Why do hailstones get so big? Scientists are chasing storms to find answers pp. 19-19

Alexandra Witze

The ‘pivot penalty’: scientists get cited less after switching fields, analysis finds pp. 20-20

Mariana Lenharo

How a mysterious epidemic of kidney disease is killing thousands of young men pp. 22-25

Carrie Arnold

Exclusive: Inside the thriving wild-animal markets that could start the next pandemic pp. 26-28

Jane Qiu

The polar regions hold crucial scientific secrets — and the time to study them is running out pp. 29-30

Marc Macias-Fauria

A walk down memory lane and other stirring stories: Books in brief pp. 30-30

Andrew Robinson

How to keep astronauts healthy in deep space pp. 31-33

Farhan M. Asrar

Why we should protect the high seas from all extraction, forever pp. 34-37

Callum M. Roberts, Emilia Dyer, Sylvia A. Earle, Andrew Forrest, Julie P. Hawkins, Ove Hoegh-Guldberg, Jessica J. Meeuwig, Daniel Pauly, Stuart L. Pimm, U. Rashid Sumaila, Johan Rockström and Mark Lynas

US–China tariff war threatens global public health pp. 38-38

Sijia Liu and Jialao Ma

Trade wars could affect food security in low-income nations pp. 38-38

Huijie Li, Bingcheng Si, Tegbaru Gobezie and Asim Biswas

Address the psychological toll of kidney disease pp. 38-38

Rongkang Li, Lei Peng, Shaohua Zhang and Song Wu

European Union’s strict conservation targets should guide global marine policy pp. 38-38

Barbara Horta e Costa, Fabrice Stephenson and Joachim Claudet

Microbial molecule of ageing gut nudges blood stem cells towards cancer pp. 39-41

Johann-Christoph Jann and Zuzana Tothova

Underwater kelp forests are losing a turf war pp. 40-40

Holly Smith

Ancient carbon released through modern rivers pp. 41-42

Li Li

The evolutionary origin of sensitive dental structures pp. 42-44

Guillaume Houée and Philippe Janvier

Blocking a key node in cancer signalling unlocks therapeutic potential pp. 44-45

Hugo Lavoie and Marc Therrien

Unexpected clustering pattern in dwarf galaxies challenges formation models pp. 47-52

Ziwen Zhang, Yangyao Chen, Yu Rong, Huiyuan Wang, Houjun Mo, Xiong Luo and Hao Li

Observing anyonization of bosons in a quantum gas pp. 53-57

Sudipta Dhar, Botao Wang, Milena Horvath, Amit Vashisht, Yi Zeng, Mikhail B. Zvonarev, Nathan Goldman, Yanliang Guo, Manuele Landini and Hanns-Christoph Nägerl

Bulk superconductivity near 40 K in hole-doped SmNiO2 at ambient pressure pp. 58-63

S. Lin Er Chow, Zhaoyang Luo and A. Ariando

Electrical switching of a p-wave magnet pp. 64-70

Qian Song, Srdjan Stavrić, Paolo Barone, Andrea Droghetti, Daniil S. Antonenko, Jörn W. F. Venderbos, Connor A. Occhialini, Batyr Ilyas, Emre Ergeçen, Nuh Gedik, Sang-Wook Cheong, Rafael M. Fernandes, Silvia Picozzi and Riccardo Comin

Unconventional solitonic high-temperature superfluorescence from perovskites pp. 71-77

Melike Biliroglu, Mustafa Türe, Antonia Ghita, Myratgeldi Kotyrov, Xixi Qin, Dovletgeldi Seyitliyev, Natchanun Phonthiptokun, Malek Abdelsamei, Jingshan Chai, Rui Su, Uthpala Herath, Anna K. Swan, Vasily V. Temnov, Volker Blum, Franky So and Kenan Gundogdu

A Nd@C82–polymer interface for efficient and stable perovskite solar cells pp. 78-84

Yuexin Lin, Zhichao Lin, Shili Lv, Yuan Shui, Wenjing Zhu, Zuhong Zhang, Wenhan Yang, Jinbo Zhao, Hao Gu, Junmin Xia, Danning Wang, Fenqi Du, Annan Zhu, Jin Liu, Hairui Cai, Bin Wang, Nan Zhang, Haibin Wang, Xiaolong Liu, Tao Liu, Chuncai Kong, Di Zhou, Shi Chen, Zhimao Yang, Tao Li, Wei Ma, Guojia Fang, Luis Echegoyen, Guichuan Xing, Shengchun Yang, Tao Yang, Wenting Cai, Meng Li, Wei Huang and Chao Liang

Stereoretentive radical cross-coupling pp. 85-91

Jiawei Sun, Jiayan He, Luca Massaro, David A. Cagan, Jet Tsien, Yu Wang, Flynn C. Attard, Jillian E. Smith, Jason S. Lee, Yu Kawamata and Phil S. Baran

C-to-N atom swapping and skeletal editing in indoles and benzofurans pp. 92-98

Zhe Wang, Pengwei Xu, Shu-Min Guo, Constantin G. Daniliuc and Armido Studer

Dating the evolution of oxygenic photosynthesis using La-Ce geochronology pp. 99-104

Laureline A. Patry, Pierre Bonnand, Maud Boyet, Munira Afroz, Dylan T. Wilmeth, Brittany Ramsay, Philippe Nonnotte, Martin Homann, Pierre Sansjofre, Philip W. Fralick and Stefan V. Lalonde

Old carbon routed from land to the atmosphere by global river systems pp. 105-111

Joshua F. Dean, Gemma Coxon, Yanchen Zheng, Jack Bishop, Mark H. Garnett, David Bastviken, Valier Galy, Robert G. M. Spencer, Suzanne E. Tank, Edward T. Tipper, Jorien E. Vonk, Marcus B. Wallin, Liwei Zhang, Chris D. Evans and Robert G. Hilton

Long-term impact and biological recovery in a deep-sea mining track pp. 112-118

Daniel O. B. Jones, Maria Belen Arias, Loïc Van Audenhaege, Sabena Blackbird, Corie Boolukos, Guadalupe Bribiesca-Contreras, Jonathan T. Copley, Andrew Dale, Susan Evans, Bethany F. M. Fleming, Andrew R. Gates, Hannah Grant, Mark G. J. Hartl, Veerle A. I. Huvenne, Rachel M. Jeffreys, Pierre Josso, Lucas D. King, Erik Simon-Lledó, Tim Le Bas, Louisa Norman, Bryan O’Malley, Thomas Peacock, Tracy Shimmield, Eva C. D. Stewart, Andrew K. Sweetman, Catherine Wardell, Dmitry Aleynik and Adrian G. Glover

The origin of vertebrate teeth and evolution of sensory exoskeletons pp. 119-124

Yara Haridy, Sam C. P. Norris, Matteo Fabbri, Karma Nanglu, Neelima Sharma, James F. Miller, Mark Rivers, Patrick Riviere, Phillip Vargas, Javier Ortega-Hernández and Neil H. Shubin

Picuris Pueblo oral history and genomics reveal continuity in US Southwest pp. 125-132

Thomaz Pinotti, Michael A. Adler, Richard Mermejo, Julie Bitz-Thorsen, Hugh McColl, Gabriele Scorrano, Motahareh Feizabadifarahani, Devlin Gandy, Matthew Boulanger, Charleen Gaunitz, Jesper Stenderup, Abigail Ramsøe, Thorfinn Korneliussen, Fabrice Demeter, Fabrício R. Santos, Lasse Vinner, Martin Sikora, David J. Meltzer, J. Víctor Moreno-Mayar, Craig Quanchello and Eske Willerslev

Adversarial testing of global neuronal workspace and integrated information theories of consciousness pp. 133-142

Oscar Ferrante, Urszula Gorska-Klimowska, Simon Henin, Rony Hirschhorn, Aya Khalaf, Alex Lepauvre, Ling Liu, David Richter, Yamil Vidal, Niccolò Bonacchi, Tanya Brown, Praveen Sripad, Marcelo Armendariz, Katarina Bendtz, Tara Ghafari, Dorottya Hetenyi, Jay Jeschke, Csaba Kozma, David R. Mazumder, Stephanie Montenegro, Alia Seedat, Abdelrahman Sharafeldin, Shujun Yang, Sylvain Baillet, David J. Chalmers, Radoslaw M. Cichy, Francis Fallon, Theofanis I. Panagiotaropoulos, Hal Blumenfeld, Floris P. Lange, Sasha Devore, Ole Jensen, Gabriel Kreiman, Huan Luo, Melanie Boly, Stanislas Dehaene, Christof Koch, Giulio Tononi, Michael Pitts, Liad Mudrik and Lucia Melloni

Human assembloid model of the ascending neural sensory pathway pp. 143-153

Ji-il Kim, Kent Imaizumi, Ovidiu Jurjuț, Kevin W. Kelley, Dong Wang, Mayuri Vijay Thete, Zuzana Hudacova, Neal D. Amin, Rebecca J. Levy, Grégory Scherrer and Sergiu P. Pașca

Serotonin and neurotensin inputs in the vCA1 dictate opposing social valence pp. 154-164

Julia M. Zorab, Huanhuan Li, Richa Awasthi, Anna Schinasi, Yoonjeong Cho, Thomas O’Loughlin and Xiaoting Wu

The P-loop NTPase RUVBL2 is a conserved clock component across eukaryotes pp. 165-173

Meimei Liao, Yanqin Liu, Zhancong Xu, Mingxu Fang, Ziqing Yu, Yufan Cui, Zhengda Sun, Ran Huo, Jieyu Yang, Fusheng Huang, Mingming Liu, Qin Zhou, Xiaocui Song, Hui Han, She Chen, Xiaodong Xu, Ximing Qin, Qun He, Dapeng Ju, Tao Wang, Nirav Thakkar, Paul E. Hardin, Susan S. Golden and Eric Erquan Zhang

Automated loss of pulse detection on a consumer smartwatch pp. 174-181

Kamal Shah, Anran Wang, Yiwen Chen, Jitender Munjal, Sumeet Chhabra, Anthony Stange, Enxun Wei, Tuan Phan, Tracy Giest, Beszel Hawkins, Dinesh Puppala, Elsina Silver, Lawrence Cai, Shruti Rajagopalan, Edward Shi, Yun-Ling Lee, Matt Wimmer, Pramod Rudrapatna, Thomas Rea, Shelten Yuen, Anupam Pathak, Shwetak Patel, Mark Malhotra, Marc Stogaitis, Jeanie Phan, Bakul Patel, Adam Vasquez, Christina Fox, Alistair Connell, Jim Taylor, Jacqueline Shreibati, David Miller, Daniel McDuff, Pushmeet Kohli, Tajinder Gadh and Jake Sunshine

Genomic determinants of antigen expression hierarchy in African trypanosomes pp. 182-190

Zhibek Keneskhanova, Kirsty R. McWilliam, Raúl O. Cosentino, Anna Barcons-Simon, Atai Dobrynin, Jaclyn E. Smith, Ines Subota, Monica R. Mugnier, Maria Colomé-Tatché and T. Nicolai Siegel

Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3 pp. 191-200

Kelvin Y. Chen, Tatsuya Kibayashi, Ambre Giguelay, Mayu Hata, Shunsuke Nakajima, Norihisa Mikami, Yusuke Takeshima, Kenji Ichiyama, Ryusuke Omiya, Leif S. Ludwig, Kunihiro Hattori and Shimon Sakaguchi

Microbial metabolite drives ageing-related clonal haematopoiesis via ALPK1 pp. 201-211

Puneet Agarwal, Avery Sampson, Kathleen Hueneman, Kwangmin Choi, Niels Asger Jakobsen, Emma Uible, Chiharu Ishikawa, Jennifer Yeung, Lyndsey Bolanos, Xueheng Zhao, Kenneth D. Setchell, David B. Haslam, Jessica Galloway-Pena, John C. Byrd, Paresh Vyas and Daniel T. Starczynowski

Spatial mapping of transcriptomic plasticity in metastatic pancreatic cancer pp. 212-221

Guangsheng Pei, Jimin Min, Kimal I. Rajapakshe, Vittorio Branchi, Yunhe Liu, Benson Chellakkan Selvanesan, Fredrik Thege, Dorsay Sadeghian, Daiwei Zhang, Kyung Serk Cho, Yanshuo Chu, Enyu Dai, Guangchun Han, Mingyao Li, Cassian Yee, Kazuki Takahashi, Bharti Garg, Herve Tiriac, Vincent Bernard, Alexander Semaan, Jean L. Grem, Thomas C. Caffrey, Jared K. Burks, Andrew M. Lowy, Andrew J. Aguirre, Paul M. Grandgenett, Michael A. Hollingsworth, Paola A. Guerrero, Linghua Wang and Anirban Maitra

Multimodal cell maps as a foundation for structural and functional genomics pp. 222-231

Leah V. Schaffer, Mengzhou Hu, Gege Qian, Kyung-Mee Moon, Abantika Pal, Neelesh Soni, Andrew P. Latham, Laura Pontano Vaites, Dorothy Tsai, Nicole M. Mattson, Katherine Licon, Robin Bachelder, Anthony Cesnik, Ishan Gaur, Trang Le, William Leineweber, Aji Palar, Ernst Pulido, Yue Qin, Xiaoyu Zhao, Christopher Churas, Joanna Lenkiewicz, Jing Chen, Keiichiro Ono, Dexter Pratt, Peter Zage, Ignacia Echeverria, Andrej Sali, J. Wade Harper, Steven P. Gygi, Leonard J. Foster, Edward L. Huttlin, Emma Lundberg and Trey Ideker

Targeting the SHOC2–RAS interaction in RAS-mutant cancers pp. 232-241

Zachary J. Hauseman, Frédéric Stauffer, Kim S. Beyer, Sandra Mollé, Elena Cavicchioli, Jean-Remy Marchand, Michelle Fodor, Jessica Viscomi, Anxhela Dhembi, Stéphanie Katz, Beatrice Faggion, Mylene Lanter, Grainne Kerr, Daniela Schildknecht, Cornelia Handl, Danilo Maddalo, Carole Pissot Soldermann, Jacob Brady, Om Shrestha, Zachary Nguyen, Lukas Leder, Gregor Cremosnik, Sandra Lopez Romero, Ulrich Hassiepen, Travis Stams, Markus Linder, Giorgio G. Galli, Daniel A. Guthy, Daniel A. King, Sauveur-Michel Maira, Claudio R. Thoma, Veronika Ehmke and Luca Tordella

Structural basis of lipid transfer by a bridge-like lipid-transfer protein pp. 242-249

Yunsik Kang, Katherine S. Lehmann, Hannah Long, Amanda Jefferson, Maria Purice, Marc Freeman and Sarah Clark

Complex water networks visualized by cryogenic electron microscopy of RNA pp. 250-259

Rachael C. Kretsch, Shanshan Li, Grigore Pintilie, Michael Z. Palo, David A. Case, Rhiju Das, Kaiming Zhang and Wah Chiu

‘I don’t have the bandwidth’: how to juggle dating alongside a PhD pp. 261-262

Gemma Conroy

Speeding up ginseng growth to aid drug discovery pp. 264-264

Rachel Brazil