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2006, volume 441, articles 7097

Academy affirms hockey-stick graph pp. 1032-1033

Geoff Brumfiel

Experts comb tropics for clues to vCJD pp. 1033-1033

Helen Pearson

Hunt for AIDS vaccine tackles genomes pp. 1034-1035

Erika Check

Hungary's science academy slammed as ‘obsolete’ pp. 1034-1034

Quirin Schiermeier

Human eggs supply ‘ethical’ stem cells pp. 1038-1038

Jo Marchant

Market watch pp. 1047-1047

Colin Macilwain

Seeing is believing as brain reveals its adaptability pp. 1048-1048

Oliver Sacks and Ralph M. Siegel

Discrete reminder about Weismann's discovery pp. 1048-1048

William L. Abler

Researchers frustrated by lack of input to NIH policy pp. 1048-1048

Don C. Rockey

Public will fear biological accidents, not just attacks pp. 1048-1048

Markus Schmidt

Faster, better, healthier pp. 1049-1050

Michael A. Goldman

A glimpse of the early Universe pp. 1050-1051

Patrick Petitjean

A question of taste pp. 1051-1051

John Piggott

Atomic gas in flatland pp. 1053-1054

Tilman Esslinger and Gianni Blatter

RNA switches function pp. 1054-1055

Steve Reichow and Gabriele Varani

Germanium takes holey orders pp. 1055-1056

Andreas Stein

Supernovae brought to light pp. 1056-1057

Carl Heiles

Pink, parkin and the brain pp. 1058-1058

Leo Pallanck and J. Timothy Greenamyre

Stem-cell Biology pp. 1059-1059

Natalie DeWitt

A glossary for stem-cell biology pp. 1060-1060

Austin Smith

Nuclear reprogramming and pluripotency pp. 1061-1067

Konrad Hochedlinger and Rudolf Jaenisch

Asymmetric and symmetric stem-cell divisions in development and cancer pp. 1068-1074

Sean J. Morrison and Judith Kimble

The stem-cell niche as an entity of action pp. 1075-1079

David T. Scadden

Stem cells, ageing and the quest for immortality pp. 1080-1086

Thomas A. Rando

Generation of neuronal variability and complexity pp. 1087-1093

Alysson R. Muotri and Fred H. Gage

Stem cells for the treatment of neurological disorders pp. 1094-1096

Olle Lindvall and Zaal Kokaia

Potential of stem-cell-based therapies for heart disease pp. 1097-1099

Deepak Srivastava and Kathryn N. Ivey

Stem-cell therapies for blood diseases pp. 1100-1102

Claudio Bordignon

Genetic evidence for complex speciation of humans and chimpanzees pp. 1103-1108

Nick Patterson, Daniel J. Richter, Sante Gnerre, Eric S. Lander and David Reich

Ovulated oocytes in adult mice derive from non-circulating germ cells pp. 1109-1114

Kevin Eggan, Sara Jurga, Roger Gosden, Irene M. Min and Amy J. Wagers

Soft equations of state for neutron-star matter ruled out by EXO 0748 - 676 pp. 1115-1117

F. Özel

Berezinskii–Kosterlitz–Thouless crossover in a trapped atomic gas pp. 1118-1121

Zoran Hadzibabic, Peter Krüger, Marc Cheneau, Baptiste Battelier and Jean Dalibard

Mesostructured germanium with cubic pore symmetry pp. 1122-1125

Gerasimos S. Armatas and Mercouri G. Kanatzidis

Hexagonal nanoporous germanium through surfactant-driven self-assembly of Zintl clusters pp. 1126-1130

Dong Sun, Andrew E. Riley, Ashley J. Cadby, Erik K. Richman, Scott D. Korlann and Sarah H. Tolbert

Subcontinental-scale crustal velocity changes along the Pacific–North America plate boundary pp. 1131-1134

J. L. Davis, B. P. Wernicke, S. Bisnath, N. A. Niemi and P. Elósegui

Seismic waves increase permeability pp. 1135-1138

Jean E. Elkhoury, Emily E. Brodsky and Duncan C. Agnew

Diversity and dispersal interactively affect predictability of ecosystem function pp. 1139-1143

Kristin E. France and J. Emmett Duffy

Activity-dependent dynamics and sequestration of proteasomes in dendritic spines pp. 1144-1148

Baris Bingol and Erin M. Schuman

Nodulation independent of rhizobia induced by a calcium-activated kinase lacking autoinhibition pp. 1149-1152

Cynthia Gleason, Shubho Chaudhuri, Tianbao Yang, Alfonso Muñoz, B. W. Poovaiah and Giles E. D. Oldroyd

Deregulation of a Ca2+/calmodulin-dependent kinase leads to spontaneous nodule development pp. 1153-1156

Leïla Tirichine, Haruko Imaizumi-Anraku, Satoko Yoshida, Yasuhiro Murakami, Lene H. Madsen, Hiroki Miwa, Tomomi Nakagawa, Niels Sandal, Anita S. Albrektsen, Masayoshi Kawaguchi, Allan Downie, Shusei Sato, Satoshi Tabata, Hiroshi Kouchi, Martin Parniske, Shinji Kawasaki and Jens Stougaard

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin pp. 1157-1161

Jeehye Park, Sung Bae Lee, Sungkyu Lee, Yongsung Kim, Saera Song, Sunhong Kim, Eunkyung Bae, Jaeseob Kim, Minho Shong, Jin-Man Kim and Jongkyeong Chung

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin pp. 1162-1166

Ira E. Clark, Mark W. Dodson, Changan Jiang, Joseph H. Cao, Jun R. Huh, Jae Hong Seol, Soon Ji Yoo, Bruce A. Hay and Ming Guo

Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch pp. 1167-1171

Alexander Serganov, Anna Polonskaia, Anh Tuân Phan, Ronald R. Breaker and Dinshaw J. Patel

Structure of the S-adenosylmethionine riboswitch regulatory mRNA element pp. 1172-1175

Rebecca K. Montange and Robert T. Batey

Retraction Note: Induction of DNA methylation and gene silencing by short interfering RNAs in human cells pp. 1176-1176

Hiroaki Kawasaki and Kazunari Taira

Divide and conquer pp. 1179-1179

Michael Eisenstein

Research assessment threatens to reshuffle UK funding pp. 1191-1191

Paul Smaglik

Gary Borisy, director and chief executive, Marine Biological Laboratory, Woods Hole, Massachusetts pp. 1192-1192

Virginia Gewin

Networks work pp. 1192-1192

Denis Bilotta

Goooaaalll! A PhD! pp. 1192-1192

Milan de Vries

Finding a happy medium pp. 1194-1194

John Gilbey

2006, volume 441, articles 7096

Sleep in continuously active dolphins pp. E9-E10

Yuske Sekiguchi, Kazutoshi Arai and Shiro Kohshima

Activity and sleep in dolphins pp. E10-E11

Guido Gnone, Tiziana Moriconi and Giorgia Gambini

Sleep in continuously active dolphins; Activity and sleep in dolphins (Reply) pp. E11-E11

O. I. Lyamin, J. Pryaslova, V. Lance and J. M. Siegel

Doomsday food store takes pole position pp. 912-913

Jacqueline Ruttimann

Tissue-sample payments anger lawmakers pp. 912-912

Erika Check

Open-access journal hits rocky times pp. 914-914

Declan Butler

Congress pushes plan to make papers free pp. 915-915

Gene Russo

Plan to rank universities fails to impress pp. 917-917

Jim Giles

From microscope to multiplex - An MRI scanner darkly pp. 922-924

John Whitfield

From microscope to multiplex - Betrayal at the bench pp. 924-925

Alison Abbott

The tiger's retreat pp. 927-930

Erika Check

Misconduct: lack of action provokes web accusations pp. 932-932

Shi-min Fang

Misconduct: exposure is not like Cultural Revolution pp. 932-932

Zheng Huang

Misconduct: Chinese funding body unmoved pp. 932-932

Ushma Savla Neill

Education and training put Iran ahead of richer states pp. 932-932

Mohammad Reza Mohebbi and Mehri Mohebbi

Lessons from Italy pp. 933-934

Brian Greenwood

Life under the microscope pp. 934-934

Jane Maienschein

A weird, wired world pp. 935-935

Vlatko Vedral

Trust in fish pp. 937-938

Lee Alan Dugatkin

Magnetic accretion pp. 938-938

Daniel Proga

The Golgi grows up pp. 939-940

Vivek Malhotra and Satyajit Mayor

Designs on Rubisco pp. 940-941

Howard Griffiths

Relaxors go critical pp. 941-942

R. E. Cohen

A second chance for the thymus pp. 942-943

Hans-Reimer Rodewald

Self-fertilization strategy in an orchid pp. 945-946

Ke-Wei Liu, Zhong-Jian Liu, LaiQiang Huang, Li-Qiang Li, Li-Jun Chen and Guang-Da Tang

Lasers producing tailored beams pp. 946-946

Eiji Miyai, Kyosuke Sakai, Takayuki Okano, Wataru Kunishi, Dai Ohnishi and Susumu Noda

Genetic mechanisms and evolutionary significance of natural variation in Arabidopsis pp. 947-952

Thomas Mitchell-Olds and Johanna Schmitt

The magnetic nature of disk accretion onto black holes pp. 953-955

Jon M. Miller, John Raymond, Andy Fabian, Danny Steeghs, Jeroen Homan, Chris Reynolds, Michiel van der Klis and Rudy Wijnands

The giant electromechanical response in ferroelectric relaxors as a critical phenomenon pp. 956-959

Z. Kutnjak, J. Petzelt and R. Blinc

Broad-band optical parametric gain on a silicon photonic chip pp. 960-963

Mark A. Foster, Amy C. Turner, Jay E. Sharping, Bradley S. Schmidt, Michal Lipson and Alexander L. Gaeta

The Southern Ocean biogeochemical divide pp. 964-967

I. Marinov, A. Gnanadesikan, J. R. Toggweiler and J. L. Sarmiento

Interseismic strain accumulation and the earthquake potential on the southern San Andreas fault system pp. 968-971

Yuri Fialko

A lamprey from the Cretaceous Jehol biota of China pp. 972-974

Mee-mann Chang, Jiangyong Zhang and Desui Miao

Image scoring and cooperation in a cleaner fish mutualism pp. 975-978

Redouan Bshary and Alexandra S. Grutter

Experience-dependent and cell-type-specific spine growth in the neocortex pp. 979-983

Anthony Holtmaat, Linda Wilbrecht, Graham W. Knott, Egbert Welker and Karel Svoboda

Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells pp. 984-987

Patricia M. White, Angelika Doetzlhofer, Yun Shain Lee, Andrew K. Groves and Neil Segil

Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium pp. 988-991

Simona W. Rossi, William E. Jenkinson, Graham Anderson and Eric J. Jenkinson

Formation of a functional thymus initiated by a postnatal epithelial progenitor cell pp. 992-996

Conrad C. Bleul, Tatiana Corbeaux, Alexander Reuter, Paul Fisch, Jürgen Schulte Mönting and Thomas Boehm

Nanog promotes transfer of pluripotency after cell fusion pp. 997-1001

José Silva, Ian Chambers, Steven Pollard and Austin Smith

Golgi maturation visualized in living yeast pp. 1002-1006

Eugene Losev, Catherine A. Reinke, Jennifer Jellen, Daniel E. Strongin, Brooke J. Bevis and Benjamin S. Glick

Live imaging of yeast Golgi cisternal maturation pp. 1007-1010

Kumi Matsuura-Tokita, Masaki Takeuchi, Akira Ichihara, Kenta Mikuriya and Akihiko Nakano

Increased cell-to-cell variation in gene expression in ageing mouse heart pp. 1011-1014

Rumana Bahar, Claudia H. Hartmann, Karl A. Rodriguez, Ashley D. Denny, Rita A. Busuttil, Martijn E. T. Dollé, R. Brent Calder, Gary B. Chisholm, Brad H. Pollock, Christoph A. Klein and Jan Vijg

Smad4 signalling in T cells is required for suppression of gastrointestinal cancer pp. 1015-1019

Byung-Gyu Kim, Cuiling Li, Wenhui Qiao, Mizuko Mamura, Barbara Kasperczak, Miriam Anver, Lawrence Wolfraim, Suntaek Hong, Elizabeth Mushinski, Michael Potter, Seong-Jin Kim, Xin-Yuan Fu, Chuxia Deng and John J. Letterio

Guidelines for physician-scientists call for training reform pp. 1021-1021

Paul Smaglik

Rules rule pp. 1022-1023

Hannah Hoag

Paul Gilna, executive director, Community Cyberinfrastructure for Advanced Marine Microbial Ecology Research and Analysis (CAMERA) project, San Diego, California pp. 1024-1024

Virginia Gewin

Lessons from the jungle pp. 1024-1024

Ayres Christ

Write and wrong pp. 1024-1024

Katja Bargum

Check elastic before jumping pp. 1026-1026

Neal Asher

2006, volume 441, articles 7095

Koreans admit disguising stem-cell lines pp. 790-791

David Cyranoski and Erika Check

Science academies target G8 agenda pp. 790-790

Declan Butler

Cash for papers: putting a premium on publication pp. 792-792

Ichiko Fuyuno and David Cyranoski

Goal fever at the World Cup pp. 793-793

Michael Hopkin

Born or made? Debate on mouse eggs reignites pp. 795-795

Kendall Powell

Atlantic in bloom pp. 798-798

Jim Giles

US satellite system loses climate sensors pp. 798-798

Jacqueline Ruttimann

The tipping point of the iceberg pp. 802-805

Gabrielle Walker

Eat your cake and have it pp. 807-809

Laura Spinney

Market watch pp. 811-811

Colin Macilwain

Women editors: change comes from focused action pp. 812-812

Linda G. Baum

Women editors: we need more female scientists pp. 812-812

Sarah P. Otto

Women editors: nominees turned down Evolution job pp. 812-812

Don Waller

‘Referee factor’ would reward a vital contribution pp. 812-812

Rory Wilson

Still light-years away from articulating the infinite pp. 812-812

Ian Stewart

In your own image pp. 813-814

Kenneth M. Weiss and Anne V. Buchanan

Reaching for the stars pp. 814-814

Giovanni Bignami

A growing urban problem pp. 815-815

Frank Schweitzer

A healthy interest pp. 815-816

W. F. Bynum

Science in culture: Home from home pp. 816-816

Colin Martin

Images from the surface of HIV pp. 817-818

Dennis R. Burton

Oxygen breaks into carbon world pp. 818-819

Pulickel M. Ajayan and Boris I. Yakobson

Good riddance to bad rubbish pp. 819-820

Daniel J. Klionsky

United through repulsion pp. 820-821

Leonardo Fallani and Massimo Inguscio

Silk spin-off pp. 821-821

Helen Dell

Best to go with what you know? pp. 822-823

Daeyeol Lee

A glass of carbon dioxide pp. 823-823

Paul F. McMillan

Bruce Merrifield (1921–2006) pp. 824-824

Stephen Kent

Accretion of the Earth and segregation of its core pp. 825-833

Bernard J. Wood, Michael J. Walter and Jonathan Wade

A common mass scaling for satellite systems of gaseous planets pp. 834-839

Robin M. Canup and William R. Ward

Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise pp. 840-846

John R. S. Newman, Sina Ghaemmaghami, Jan Ihmels, David K. Breslow, Matthew Noble, Joseph L. DeRisi and Jonathan S. Weissman

Distribution and three-dimensional structure of AIDS virus envelope spikes pp. 847-852

Ping Zhu, Jun Liu, Julian Bess, Elena Chertova, Jeffrey D. Lifson, Henry Grisé, Gilad A. Ofek, Kenneth A. Taylor and Kenneth H. Roux

Repulsively bound atom pairs in an optical lattice pp. 853-856

K. Winkler, G. Thalhammer, F. Lang, R. Grimm, J. Hecker Denschlag, A. J. Daley, A. Kantian, H. P. Büchler and P. Zoller

Amorphous silica-like carbon dioxide pp. 857-860

Mario Santoro, Federico A. Gorelli, Roberto Bini, Giancarlo Ruocco, Sandro Scandolo and Wilson A. Crichton

Control of four stereocentres in a triple cascade organocatalytic reaction pp. 861-863

Dieter Enders, Matthias R. M. Hüttl, Christoph Grondal and Gerhard Raabe

The importance of the diurnal and annual cycle of air traffic for contrail radiative forcing pp. 864-867

Nicola Stuber, Piers Forster, Gaby Rädel and Keith Shine

Speciation by hybridization in Heliconius butterflies pp. 868-871

Jesús Mavárez, Camilo A. Salazar, Eldredge Bermingham, Christian Salcedo, Chris D. Jiggins and Mauricio Linares

Sperm storage induces an immunity cost in ants pp. 872-875

Boris Baer, Sophie A. O. Armitage and Jacobus J. Boomsma

Cortical substrates for exploratory decisions in humans pp. 876-879

Nathaniel D. Daw, John P. O'Doherty, Peter Dayan, Ben Seymour and Raymond J. Dolan

Loss of autophagy in the central nervous system causes neurodegeneration in mice pp. 880-884

Masaaki Komatsu, Satoshi Waguri, Tomoki Chiba, Shigeo Murata, Jun-ichi Iwata, Isei Tanida, Takashi Ueno, Masato Koike, Yasuo Uchiyama, Eiki Kominami and Keiji Tanaka

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice pp. 885-889

Taichi Hara, Kenji Nakamura, Makoto Matsui, Akitsugu Yamamoto, Yohko Nakahara, Rika Suzuki-Migishima, Minesuke Yokoyama, Kenji Mishima, Ichiro Saito, Hideyuki Okano and Noboru Mizushima

Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells pp. 890-893

Matthew A. Williams, Aaron J. Tyznik and Michael J. Bevan

Signal peptide peptidase is required for dislocation from the endoplasmic reticulum pp. 894-897

Joana Loureiro, Brendan N. Lilley, Eric Spooner, Vanessa Noriega, Domenico Tortorella and Hidde L. Ploegh

CRD-BP mediates stabilization of βTrCP1 and c-myc mRNA in response to β-catenin signalling pp. 898-901

Felicite K. Noubissi, Irina Elcheva, Neehar Bhatia, Abbas Shakoori, Andrei Ougolkov, Jianghuai Liu, Toshinari Minamoto, Jeff Ross, Serge Y. Fuchs and Vladimir S. Spiegelman

Correction: Corrigendum: A brain-specific microRNA regulates dendritic spine development pp. 902-902

Gerhard M. Schratt, Fabian Tuebing, Elizabeth A. Nigh, Christina G. Kane, Mary E. Sabatini, Michael Kiebler and Michael E. Greenberg

Correction: Corrigendum: Brain-state- and cell-type-specific firing of hippocampal interneurons in vivo pp. 902-902

Thomas Klausberger, Peter J. Magill, László F. Márton, J. David B. Roberts, Philip M. Cobden, György Buzsáki and Peter Somogyi

Correction: Corrigendum: Universal scaling of respiratory metabolism, size and nitrogen in plants pp. 902-902

Peter B. Reich, Mark G. Tjoelker, Jose-Luis Machado and Jacek Oleksyn

Taking a break can lend focus pp. 903-903

Paul Smaglik

Nicholas Schork, director, Center for Biomedical Informatics; co-director, Cancer Genetics Program, University of California, San Diego pp. 904-904

Virginia Gewin

A physics walkabout pp. 904-904

Charles Tahan

Graduation joy pp. 904-904

Andreas Andersson

Great unreported discoveries no. 163 pp. 906-906

Mike Resnick

2006, volume 441, articles 7094

Complexity of excited-state dynamics in DNA pp. E7-E7

Dimitra Markovitsi, Francis Talbot, Thomas Gustavsson, Delphine Onidas, Elodie Lazzarotto and Sylvie Marguet

Complexity of excited-state dynamics in DNA (Reply) pp. E8-E8

Carlos E. Crespo-Hernández, Boiko Cohen and Bern Kohler

EU science fund targets young guns pp. 672-672

Alison Abbott

Disasters drive DNA forensics to reunite families pp. 673-673

Claire Ainsworth

Insurers' disaster files suggest climate is culprit pp. 674-674

Quirin Schiermeier

Politicians chastise Australia's science institute pp. 674-675

Carina Dennis

Sea-lion studies come to a halt after court judgement pp. 677-677

Rex Dalton

Online methods share insider tricks pp. 678-678

Helen Pearson

US scraps plan to license foreign scientists pp. 679-679

Geoff Brumfiel

The gene weavers pp. 683-685

Garry Hamilton

Culture Crash pp. 686-688

Philip Ball

Biochemist strikes gold pp. 689-689

Meredith Wadman

Funding: income criterion would hit postdoc careers pp. 690-690

Phil Bland

Funding: proposals ignore mentoring and teaching pp. 690-690

John Bothwell

Funding: income is already dependent on outcome pp. 690-690

Joanna Bryson

Technology transfer is all about bringing in money pp. 690-690

W. Graham Richards

Debye's wooden response undercut Nazi orders pp. 690-690

Harvey Posvic

Europe pays the price for spending less pp. 691-693

Lord Patten

From cell to organism pp. 695-696

Alfonso Martinez Arias

Charting an Arabic course pp. 696-697

A. M. Celâl Şengör

Theatre: Would the real Mr Feynman...? pp. 697-697

Richard Webb

The eye of the beholder pp. 697-697

Richard Gregory

Synthesis with a twist pp. 699-700

Harry H. Wasserman

Respect for stromatolites pp. 700-701

Stanley M. Awramik

Transparency on an optical chip pp. 701-702

Robert W. Boyd and Daniel J. Gauthier

Extending influence pp. 702-703

Eve Marder

A hand on the aftershock trigger pp. 704-705

Ian Main

All together now pp. 705-705

Stephen J. Haswell

Rediscovery of the world's leggiest animal pp. 707-707

Paul E. Marek and Jason E. Bond

Titan Radar Mapper observations from Cassini's T3 fly-by pp. 709-713

C. Elachi, S. Wall, M. Janssen, E. Stofan, R. Lopes, R. Kirk, R. Lorenz, J. Lunine, F. Paganelli, L. Soderblom, C. Wood, L. Wye, H. Zebker, Y. Anderson, S. Ostro, M. Allison, R. Boehmer, P. Callahan, P. Encrenaz, E. Flamini, G. Francescetti, Y. Gim, G. Hamilton, S. Hensley, W. Johnson, K. Kelleher, D. Muhleman, G. Picardi, F. Posa, L. Roth, R. Seu, S. Shaffer, B. Stiles, S. Vetrella and R. West

Stromatolite reef from the Early Archaean era of Australia pp. 714-718

Abigail C. Allwood, Malcolm R. Walter, Balz S. Kamber, Craig P. Marshall and Ian W. Burch

Noise-resistant and synchronized oscillation of the segmentation clock pp. 719-723

Kazuki Horikawa, Kana Ishimatsu, Eiichi Yoshimoto, Shigeru Kondo and Hiroyuki Takeda

Stabilization of the disk around β Pictoris by extremely carbon-rich gas pp. 724-726

Aki Roberge, Paul D. Feldman, Alycia J. Weinberger, Magali Deleuil and Jean-Claude Bouret

A constitutive law for dense granular flows pp. 727-730

Pierre Jop, Yoël Forterre and Olivier Pouliquen

Synthesis and structural analysis of 2-quinuclidonium tetrafluoroborate pp. 731-734

Kousuke Tani and Brian M. Stoltz

Decay of aftershock density with distance indicates triggering by dynamic stress pp. 735-738

K. R. Felzer and E. E. Brodsky

Bone histology indicates insular dwarfism in a new Late Jurassic sauropod dinosaur pp. 739-741

P. Martin Sander, Octávio Mateus, Thomas Laven and Nils Knötschke

Intensity of sexual selection along the anisogamy–isogamy continuum pp. 742-745

Adam Bjork and Scott Pitnick

Social interactions among epithelial cells during tracheal branching morphogenesis pp. 746-749

Amin S. Ghabrial and Mark A. Krasnow

Importance of SoxE in neural crest development and the evolution of the pharynx pp. 750-752

David W. McCauley and Marianne Bronner-Fraser

A dynamic role for the mushroom bodies in promoting sleep in Drosophila pp. 753-756

Jena L. Pitman, Jermaine J. McGill, Kevin P. Keegan and Ravi Allada

Sleep in Drosophila is regulated by adult mushroom bodies pp. 757-760

William J. Joiner, Amanda Crocker, Benjamin H. White and Amita Sehgal

Modulation of intracortical synaptic potentials by presynaptic somatic membrane potential pp. 761-765

Yousheng Shu, Andrea Hasenstaub, Alvaro Duque, Yuguo Yu and David A. McCormick

Germline transmission of genetically modified primordial germ cells pp. 766-769

Marie-Cecile van de Lavoir, Jennifer H. Diamond, Philip A. Leighton, Christine Mather-Love, Babette S. Heyer, Renee Bradshaw, Allyn Kerchner, Lisa T. Hooi, Terri M. Gessaro, Susan E. Swanberg, Mary E. Delany and Robert J. Etches

SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope pp. 770-773

Ghislain G. Cabal, Auguste Genovesio, Susana Rodriguez-Navarro, Christophe Zimmer, Olivier Gadal, Annick Lesne, Henri Buc, Frank Feuerbach-Fournier, Jean-Christophe Olivo-Marin, Eduard C. Hurt and Ulf Nehrbass

Nuclear pore association confers optimal expression levels for an inducible yeast gene pp. 774-778

Angela Taddei, Griet Van Houwe, Florence Hediger, Veronique Kalck, Fabien Cubizolles, Heiko Schober and Susan M. Gasser

Hustling for opportunities can overcome local disadvantages pp. 779-779

Paul Smaglik

Bound for Boston pp. 780-781

Corie Lok

Bruce Jones, chief scientist, United States Geological Survey, Washington DC pp. 782-782

Virginia Gewin

Nurturing bioincubators in the north pp. 782-782

Gene Russo

Einstein's secret diary? pp. 782-782

Mhairi Dupre

The computiful game pp. 784-784

Paul Steven Miller

2006, volume 441, articles 7093

Methane release in the Early Jurassic period (Reply) pp. E5-E6

D. B. Kemp, A. L. Coe, A. S. Cohen and L. Schwark

Methane release in the Early Jurassic period pp. E5-E5

Paul B. Wignall, John M. McArthur, Crispin T. S. Little and Anthony Hallam

Pandemic ‘dry run’ is cause for concern pp. 554-555

Declan Butler

Murders halt rainforest research pp. 555-555

Declan Butler

Old tools shed light on hobbit origins pp. 559-559

Michael Hopkin

Bad weather ahead pp. 564-566

Alexandra Witze

Cashing in on the rich coast pp. 567-569

Rex Dalton

An easy way out? pp. 570-571

Emma Marris

Giving up the big questions when answers are in sight pp. 574-574

Matt Mountain

Too many people are being displaced for Merowe dam pp. 574-574

Maurice Guéron

Can the Internet save us from epidemics? pp. 574-574

David M. Eagleman

Plant databases linked for botanists and gardeners pp. 574-574

Boyce Tankersley

People of the past should not be called primitive pp. 574-574

Megan Marie McCullen

Sex and violence in rock art pp. 575-576

Paul G. Bahn

The forgotten mathematician pp. 576-576

A. W. F. Edwards

Red in the head pp. 577-577

Josh Weisberg

Energy with meaning pp. 577-578

Ehsan Masood

Artists on a mission pp. 578-578

Colin Martin

The Arctic tells its story pp. 579-580

Heather M. Stoll

HIV goes nuclear pp. 581-582

Min Li and Robert Craigie

Critical genes in a critical region pp. 582-583

Charles J. Epstein

All in the game pp. 583-584

Thomas Pfeiffer and Martin A. Nowak

Gas in a straitjacket pp. 584-585

Susumu Kitagawa

Polar roller pp. 585-585

Paul Hanlon

Subsidence and flooding in New Orleans pp. 587-588

Timothy H. Dixon, Falk Amelung, Alessandro Ferretti, Fabrizio Novali, Fabio Rocca, Roy Dokka, Giovanni Sella, Sang-Wan Kim, Shimon Wdowinski and Dean Whitman

Visualization of quantized vortices pp. 588-588

Gregory P. Bewley, Daniel P. Lathrop and Katepalli R. Sreenivasan

A putative flip–flop switch for control of REM sleep pp. 589-594

Jun Lu, David Sherman, Marshall Devor and Clifford B. Saper

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21 pp. 595-600

Joseph R. Arron, Monte M. Winslow, Alberto Polleri, Ching-Pin Chang, Hai Wu, Xin Gao, Joel R. Neilson, Lei Chen, Jeremy J. Heit, Seung K. Kim, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Uta Francke, Isabella A. Graef and Gerald R. Crabtree

The Cenozoic palaeoenvironment of the Arctic Ocean pp. 601-605

Kathryn Moran, Jan Backman, Henk Brinkhuis, Steven C. Clemens, Thomas Cronin, Gerald R. Dickens, Frédérique Eynaud, Jérôme Gattacceca, Martin Jakobsson, Richard W. Jordan, Michael Kaminski, John King, Nalan Koc, Alexey Krylov, Nahysa Martinez, Jens Matthiessen, David McInroy, Theodore C. Moore, Jonaotaro Onodera, Matthew O'Regan, Heiko Pälike, Brice Rea, Domenico Rio, Tatsuhiko Sakamoto, David C. Smith, Ruediger Stein, Kristen St John, Itsuki Suto, Noritoshi Suzuki, Kozo Takahashi, Mahito Watanabe, Masanobu Yamamoto, John Farrell, Martin Frank, Peter Kubik, Wilfried Jokat and Yngve Kristoffersen

Episodic fresh surface waters in the Eocene Arctic Ocean pp. 606-609

Henk Brinkhuis, Stefan Schouten, Margaret E. Collinson, Appy Sluijs, Jaap S. Sinninghe Damsté, Gerald R. Dickens, Matthew Huber, Thomas M. Cronin, Jonaotaro Onodera, Kozo Takahashi, Jonathan P. Bujak, Ruediger Stein, Johan van der Burgh, James S. Eldrett, Ian C. Harding, André F. Lotter, Francesca Sangiorgi, Han van Konijnenburg-van Cittert, Jan W. de Leeuw, Jens Matthiessen, Jan Backman and Kathryn Moran

Subtropical Arctic Ocean temperatures during the Palaeocene/Eocene thermal maximum pp. 610-613

Appy Sluijs, Stefan Schouten, Mark Pagani, Martijn Woltering, Henk Brinkhuis, Jaap S. Sinninghe Damsté, Gerald R. Dickens, Matthew Huber, Gert-Jan Reichart, Ruediger Stein, Jens Matthiessen, Lucas J. Lourens, Nikolai Pedentchouk, Jan Backman and Kathryn Moran

Diapir-induced reorientation of Saturn's moon Enceladus pp. 614-616

Francis Nimmo and Robert T. Pappalardo

Dimensional reduction at a quantum critical point pp. 617-620

S. E. Sebastian, N. Harrison, C. D. Batista, L. Balicas, M. Jaime, P. A. Sharma, N. Kawashima and I. R. Fisher

Thermodynamic control of asymmetric amplification in amino acid catalysis pp. 621-623

Martin Klussmann, Hiroshi Iwamura, Suju P. Mathew, David H. Wells, Urvish Pandya, Alan Armstrong and Donna G. Blackmond

Early stone technology on Flores and its implications for Homo floresiensis pp. 624-628

Adam Brumm, Fachroel Aziz, Gert D. van den Bergh, Michael J. Morwood, Mark W. Moore, Iwan Kurniawan, Douglas R. Hobbs and Richard Fullagar

Biodiversity and ecosystem stability in a decade-long grassland experiment pp. 629-632

David Tilman, Peter B. Reich and Johannes M. H. Knops

Frequency-dependent survival in natural guppy populations pp. 633-636

Robert Olendorf, F. Helen Rodd, David Punzalan, Anne E. Houde, Carla Hurt, David N. Reznick and Kimberly A. Hughes

Assembly of the inner rod determines needle length in the type III secretion injectisome pp. 637-640

Thomas C. Marlovits, Tomoko Kubori, María Lara-Tejero, Dennis Thomas, Vinzenz M. Unger and Jorge E. Galán

The inner-nuclear-envelope protein emerin regulates HIV-1 infectivity pp. 641-645

Jean-Marc Jacque and Mario Stevenson

A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT pp. 646-650

Yousang Gwack, Sonia Sharma, Julie Nardone, Bogdan Tanasa, Alina Iuga, Sonal Srikanth, Heidi Okamura, Diana Bolton, Stefan Feske, Patrick G. Hogan and Anjana Rao

Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit pp. 651-655

Thorsten Schäfer, Bohumil Maco, Elisabeth Petfalski, David Tollervey, Bettina Böttcher, Ueli Aebi and Ed Hurt

Computational redesign of endonuclease DNA binding and cleavage specificity pp. 656-659

Justin Ashworth, James J. Havranek, Carlos M. Duarte, Django Sussman, Raymond J. Monnat, Barry L. Stoddard and David Baker

Movie depictions of scientists mirror real perceptions pp. 661-661

Paul Smaglik

Star gazing moves south pp. 662-663

Dirk Steuerwald

Nadia's nectar pp. 666-666

Ian Watson

2006, volume 441, articles 7092

Mechanisms and models of human dynamics pp. E5-E5

Alex Kentsis

Mechanisms and models of human dynamics (Reply) pp. E5-E6

J. G. Oliveira and A.-L. Barabàsi

Synthetic biologists try to calm fears pp. 388-389

Erika Check

Mars explorers seek spot for touchdown pp. 389-389

Tony Reichhardt

Teenager waits 40 years for recognition pp. 390-390

Ichiko Fuyuno

Election fever inflames the US stem-cell debate pp. 391-391

Erika Check

Named and shamed pp. 392-393

David Cyranoski

Physicists plead to make final tweak to fusion experiment pp. 394-394

Geoff Brumfiel

What is a gene? pp. 398-401

Helen Pearson

The dark side of the Sun pp. 402-404

Stuart Clark

Climate: open review may ease acceptance of report pp. 406-406

Michael MacCracken

Climate: US has always made IPCC drafts available pp. 406-406

Harlan L. Watson

HIV denialists ignore large gap in the study they cite pp. 406-406

Nathan Geffen, Nicoli Nattrass and Glenda Gray

Building on failure pp. 407-407

J. M. Ottino

A mammoth murder mystery pp. 408-408

Alan B. Shabel

Everyone hates a know-all pp. 409-409

David Philip Miller

Life, the Universe and entropy pp. 409-409

Robert J. McEliece

Science in culture: Form becomes feeling pp. 410-410

Martin Kemp

A New World of differences pp. 411-412

Shaun Miller and Jared Diamond

Paramutable possibilities pp. 413-414

Paul D. Soloway

Display of flexibility pp. 414-415

László Forró

Adaptable innate killers pp. 415-416

Peter Parham

How to make a chondrule pp. 416-417

Steve Desch

Paradox of the clumps pp. 417-418

Sean Nee and Nick Colegrave

Good, bad and reformable pp. 418-419

Viktor Janzen and David T. Scadden

Film review pp. 418-418

Maria Bellantone

Avoidance of disease by social lobsters pp. 421-421

Donald C. Behringer, Mark J. Butler and Jeffrey D. Shields

Signalling in cancer pp. 423-423

Alex Eccleston and Ritu Dhand

Ras, PI(3)K and mTOR signalling controls tumour cell growth pp. 424-430

Reuben J. Shaw and Lewis C. Cantley

Nuclear factor-κB in cancer development and progression pp. 431-436

Michael Karin

Hypoxia signalling in cancer and approaches to enforce tumour regression pp. 437-443

Jacques Pouysségur, Frédéric Dayan and Nathalie M. Mazure

New signals from the invasive front pp. 444-450

Gerhard Christofori

Validating cancer drug targets pp. 451-456

John D. Benson, Ying-Nan P. Chen, Susan A. Cornell-Kennon, Marion Dorsch, Sunkyu Kim, Magdalena Leszczyniecka, William R. Sellers and Christoph Lengauer

Mechanisms of drug inhibition of signalling molecules pp. 457-462

Judith S. Sebolt-Leopold and Jessie M. English

Long γ-ray bursts and core-collapse supernovae have different environments pp. 463-468

A. S. Fruchter, A. J. Levan, L. Strolger, P. M. Vreeswijk, S. E. Thorsett, D. Bersier, I. Burud, J. M. Castro Cerón, A. J. Castro-Tirado, C. Conselice, T. Dahlen, H. C. Ferguson, J. P. U. Fynbo, P. M. Garnavich, R. A. Gibbons, J. Gorosabel, T. R. Gull, J. Hjorth, S. T. Holland, C. Kouveliotou, Z. Levay, M. Livio, M. R. Metzger, P. E. Nugent, L. Petro, E. Pian, J. E. Rhoads, A. G. Riess, K. C. Sahu, A. Smette, N. R. Tanvir, R. A. M. J. Wijers and S. E. Woosley

RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse pp. 469-474

Minoo Rassoulzadegan, Valérie Grandjean, Pierre Gounon, Stéphane Vincent, Isabelle Gillot and François Cuzin

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells pp. 475-482

Ömer H. Yilmaz, Riccardo Valdez, Brian K. Theisen, Wei Guo, David O. Ferguson, Hong Wu and Sean J. Morrison

Chondrule formation in particle-rich nebular regions at least hundreds of kilometres across pp. 483-485

Jeffrey N. Cuzzi and Conel M. O'D. Alexander

Detection of magnetic circular dichroism using a transmission electron microscope pp. 486-488

P. Schattschneider, S. Rubino, C. Hébert, J. Rusz, J. Kuneš, P. Novák, E. Carlino, M. Fabrizioli, G. Panaccione and G. Rossi

Ge/Si nanowire heterostructures as high-performance field-effect transistors pp. 489-493

Jie Xiang, Wei Lu, Yongjie Hu, Yue Wu, Hao Yan and Charles M. Lieber

Long-term eruptive activity at a submarine arc volcano pp. 494-497

Robert W. Embley, William W. Chadwick, Edward T. Baker, David A. Butterfield, Joseph A. Resing, Cornel E.J. de Ronde, Verena Tunnicliffe, John E. Lupton, S. Kim Juniper, Kenneth H. Rubin, Robert J. Stern, Geoffrey T. Lebon, Ko-ichi Nakamura, Susan G. Merle, James R. Hein, Douglas A. Wiens and Yoshihiko Tamura

Resource competition and social conflict in experimental populations of yeast pp. 498-501

R. Craig MacLean and Ivana Gudelj

A simple rule for the evolution of cooperation on graphs and social networks pp. 502-505

Hisashi Ohtsuki, Christoph Hauert, Erez Lieberman and Martin A. Nowak

Homology of arthropod anterior appendages revealed by Hox gene expression in a sea spider pp. 506-508

Muriel Jager, Jérôme Murienne, Céline Clabaut, Jean Deutsch, Hervé Le Guyader and Michaël Manuel

Somatic stem cell niche tropism in Wolbachia pp. 509-512

Horacio M. Frydman, Jennifer M. Li, Drew N. Robson and Eric Wieschaus

S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration pp. 513-517

Takashi Uehara, Tomohiro Nakamura, Dongdong Yao, Zhong-Qing Shi, Zezong Gu, Yuliang Ma, Eliezer Masliah, Yasuyuki Nomura and Stuart A. Lipton

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention pp. 518-522

Jiwang Zhang, Justin C. Grindley, Tong Yin, Sachintha Jayasinghe, Xi C. He, Jason T. Ross, Jeffrey S. Haug, Dawn Rupp, Kimberly S. Porter-Westpfahl, Leanne M. Wiedemann, Hong Wu and Linheng Li

Identification of a tumour suppressor network opposing nuclear Akt function pp. 523-527

Lloyd C. Trotman, Andrea Alimonti, Pier Paolo Scaglioni, Jason A. Koutcher, Carlos Cordon-Cardo and Pier Paolo Pandolfi

GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission pp. 528-531

Aurélien Roux, Katherine Uyhazi, Adam Frost and Pietro De Camilli

Rec8 phosphorylation and recombination promote the step-wise loss of cohesins in meiosis pp. 532-536

Gloria A. Brar, Brendan M. Kiburz, Yi Zhang, Ji-Eun Kim, Forest White and Angelika Amon

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways pp. 537-541

Dirk Grimm, Konrad L. Streetz, Catherine L. Jopling, Theresa A. Storm, Kusum Pandey, Corrine R. Davis, Patricia Marion, Felix Salazar and Mark A. Kay

Fledgling UK postdoc association can learn from other efforts pp. 543-543

Paul Smaglik

Animal intelligence pp. 544-545

Hannah Hoag

Jai Nagarkatti, president and chief executive, Sigma-Aldrich, St Louis, Missouri pp. 546-546

Virginia Gewin

Britain's postdocs unite pp. 546-546

John Bothwell

Clocking out pp. 546-546

Milan de Vries

Paratext pp. 548-548

Scarlett Thomas

2006, volume 441, articles 7091

Toll-like receptors and antibody responses pp. E4-E4

D. Nemazee, A. Gavin, K. Hoebe and B. Beutler

Toll-like receptors and antibody responses (Reply) pp. E4-E4

C. Pasare and R. Medzhitov

Neanderthal DNA yields to genome foray pp. 260-261

Rex Dalton

Antibiotic faces uncertain future pp. 260-260

Helen Pearson

How does a painkiller harm the heart? pp. 262-262

Meredith Wadman

Blogger reveals China's migratory goose farms near site of flu outbreak pp. 263-263

Declan Butler

Economists claim carbon cuts won't break the world's bank pp. 264-265

Jim Giles

Who is Mark Myers? pp. 266-266

Emma Marris

Look and learn pp. 271-272

Apoorva Mandavilli

Batteries not included What can't bacteria do? pp. 274-277

Nick Lane

Batteries not included Circuits of slime pp. 277-279

Charlotte Schubert

Market watch pp. 281-281

Colin Macilwain

TGN1412: scrutinizing preclinical trials of antibody-based medicines pp. 282-282

Søren Hansen and R. Graham Q. Leslie

Drug giants hamstrung by timid middle management pp. 282-282

Raymond A. Firestone

ID paper wasn't impartial enough for committee pp. 282-282

Yves Gingras

Supporting the use of artemisinin in combination pp. 282-282

Victoria G. Hale

Neglected tests for neglected patients pp. 283-284

Martine Usdin, Martine Guillerm and Pierre Chirac

From here to eternity pp. 285-285

Peter Coles

A single survivor pp. 286-287

Rick Shine

Lives after death pp. 286-286

Steven Shapin

Time for a change pp. 289-289

Norman R. Pace

The Phoenix effect pp. 291-292

Kevin R. Foster

A neptunian triplet pp. 292-293

David Charbonneau

Antibiotic stops ‘ping-pong’ match pp. 293-294

Eric D. Brown

When is a metal not a metal? pp. 295-296

Steven C. Erwin

Skin care by keratins pp. 296-297

M. Bishr Omary and Nam-On Ku

Cool vibes pp. 297-298

Thomas C. Killian

Experiments in botany pp. 298-298

Henry Gee

A bug-beating diode pp. 299-299

Asif Khan

The superficial life of microbes pp. 300-302

Roberto Kolter and E. Peter Greenberg

Semantic combinations in primate calls pp. 303-303

Kate Arnold and Klaus Zuberbühler

An extrasolar planetary system with three Neptune-mass planets pp. 305-309

Christophe Lovis, Michel Mayor, Francesco Pepe, Yann Alibert, Willy Benz, François Bouchy, Alexandre C. M. Correia, Jacques Laskar, Christoph Mordasini, Didier Queloz, Nuno C. Santos, Stéphane Udry, Jean-Loup Bertaux and Jean-Pierre Sivan

Evolution of an obligate social cheater to a superior cooperator pp. 310-314

Francesca Fiegna, Yuen-Tsu N. Yu, Supriya V. Kadam and Gregory J. Velicer

The DNA sequence and biological annotation of human chromosome 1 pp. 315-321

S. G. Gregory, K. F. Barlow, K. E. McLay, R. Kaul, D. Swarbreck, A. Dunham, C. E. Scott, K. L. Howe, K. Woodfine, C. C. A. Spencer, M. C. Jones, C. Gillson, S. Searle, Y. Zhou, F. Kokocinski, L. McDonald, R. Evans, K. Phillips, A. Atkinson, R. Cooper, C. Jones, R. E. Hall, T. D. Andrews, C. Lloyd, R. Ainscough, J. P. Almeida, K. D. Ambrose, F. Anderson, R. W. Andrew, R. I. S. Ashwell, K. Aubin, A. K. Babbage, C. L. Bagguley, J. Bailey, H. Beasley, G. Bethel, C. P. Bird, S. Bray-Allen, J. Y. Brown, A. J. Brown, D. Buckley, J. Burton, J. Bye, C. Carder, J. C. Chapman, S. Y. Clark, G. Clarke, C. Clee, V. Cobley, R. E. Collier, N. Corby, G. J. Coville, J. Davies, R. Deadman, M. Dunn, M. Earthrowl, A. G. Ellington, H. Errington, A. Frankish, J. Frankland, L. French, P. Garner, J. Garnett, L. Gay, M. R. J. Ghori, R. Gibson, L. M. Gilby, W. Gillett, R. J. Glithero, D. V. Grafham, C. Griffiths, S. Griffiths-Jones, R. Grocock, S. Hammond, E. S. I. Harrison, E. Hart, E. Haugen, P. D. Heath, S. Holmes, K. Holt, P. J. Howden, A. R. Hunt, S. E. Hunt, G. Hunter, J. Isherwood, R. James, C. Johnson, D. Johnson, A. Joy, M. Kay, J. K. Kershaw, M. Kibukawa, A. M. Kimberley, A. King, A. J. Knights, H. Lad, G. Laird, S. Lawlor, D. A. Leongamornlert, D. M. Lloyd, J. Loveland, J. Lovell, M. J. Lush, R. Lyne, S. Martin, M. Mashreghi-Mohammadi, L. Matthews, N. S. W. Matthews, S. McLaren, S. Milne, S. Mistry, M. J. F. M Oore, T. Nickerson, C. N. O'Dell, K. Oliver, A. Palmeiri, S. A. Palmer, A. Parker, D. Patel, A. V. Pearce, A. I. Peck, S. Pelan, K. Phelps, B. J. Phillimore, R. Plumb, J. Rajan, C. Raymond, G. Rouse, C. Saenphimmachak, H. K. Sehra, E. Sheridan, R. Shownkeen, S. Sims, C. D. Skuce, M. Smith, C. Steward, S. Subramanian, N. Sycamore, A. Tracey, A. Tromans, Z. Van Helmond, M. Wall, J. M. Wallis, S. White, S. L. Whitehead, J. E. Wilkinson, D. L. Willey, H. Williams, L. Wilming, P. W. Wray, Z. Wu, A. Coulson, M. Vaudin, J. E. Sulston, R. Durbin, T. Hubbard, R. Wooster, I. Dunham, N. P. Carter, G. McVean, M. T. Ross, J. Harrow, M. V. Olson, S. Beck, J. Rogers and D. R. Bentley

Suppression of dwarf galaxy formation by cosmic reionization pp. 322-324

J. Stuart B. Wyithe and Abraham Loeb

An aluminium nitride light-emitting diode with a wavelength of 210 nanometres pp. 325-328

Yoshitaka Taniyasu, Makoto Kasu and Toshiki Makimoto

Links between annual, Milankovitch and continuum temperature variability pp. 329-332

Peter Huybers and William Curry

Seismic detection of folded, subducted lithosphere at the core–mantle boundary pp. 333-336

Alexander R. Hutko, Thorne Lay, Edward J. Garnero and Justin Revenaugh

Embryological evidence for developmental lability during early angiosperm evolution pp. 337-340

William E. Friedman

Copper-containing plastocyanin used for electron transport by an oceanic diatom pp. 341-344

Graham Peers and Neil M. Price

Horizontal endosymbiont transmission in hydrothermal vent tubeworms pp. 345-348

Andrea D. Nussbaumer, Charles R. Fisher and Monika Bright

Polycomb complexes repress developmental regulators in murine embryonic stem cells pp. 349-353

Laurie A. Boyer, Kathrin Plath, Julia Zeitlinger, Tobias Brambrink, Lea A. Medeiros, Tong Ihn Lee, Stuart S. Levine, Marius Wernig, Adriana Tajonar, Mridula K. Ray, George W. Bell, Arie P. Otte, Miguel Vidal, David K. Gifford, Richard A. Young and Rudolf Jaenisch

A TAS1R receptor-based explanation of sweet ‘water-taste’ pp. 354-357

Veronica Galindo-Cuspinera, Marcel Winnig, Bernd Bufe, Wolfgang Meyerhof and Paul A. S. Breslin

Platensimycin is a selective FabF inhibitor with potent antibiotic properties pp. 358-361

Jun Wang, Stephen M. Soisson, Katherine Young, Wesley Shoop, Srinivas Kodali, Andrew Galgoci, Ronald Painter, Gopalakrishnan Parthasarathy, Yui S. Tang, Richard Cummings, Sookhee Ha, Karen Dorso, Mary Motyl, Hiranthi Jayasuriya, John Ondeyka, Kithsiri Herath, Chaowei Zhang, Lorraine Hernandez, John Allocco, Ángela Basilio, José R. Tormo, Olga Genilloud, Francisca Vicente, Fernando Pelaez, Lawrence Colwell, Sang Ho Lee, Bruce Michael, Thomas Felcetto, Charles Gill, Lynn L. Silver, Jeffery D. Hermes, Ken Bartizal, John Barrett, Dennis Schmatz, Joseph W. Becker, Doris Cully and Sheo B. Singh

A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth pp. 362-365

Seyun Kim, Pauline Wong and Pierre A. Coulombe

Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation pp. 366-370

Lazaros C. Foukas, Marc Claret, Wayne Pearce, Klaus Okkenhaug, Stephen Meek, Emma Peskett, Sara Sancho, Andrew J. H. Smith, Dominic J. Withers and Bart Vanhaesebroeck

The mechanism of cell differentiation in Bacillus subtilis pp. 371-374

Dagmar Iber, Joanna Clarkson, Michael D. Yudkin and Iain D. Campbell

Cleavage of pre-tRNAs by the splicing endonuclease requires a composite active site pp. 375-377

Christopher R. Trotta, Sergey V. Paushkin, Meenal Patel, Hong Li and Stuart W. Peltz

Misconduct has ripple effects beyond the perpetrator pp. 379-379

Paul Smaglik

Mahendra Rao, vice-president, research, stem cells and regenerative medicine, Invitrogen, Carlsbad, California pp. 380-380

Virginia Gewin

International view from Japan pp. 380-380

Keiko Muraki

The many legs of fear pp. 380-380

Mhairi Dupre

The visible men pp. 382-382

Michael Moorcock

2006, volume 441, articles 7090

Arab state pours oil profits into science pp. 132-133

Jim Giles

Arctic stations need human touch pp. 133-133

Quirin Schiermeier

Outspoken: Mike Griffin on the NASA budget pp. 134-134

Tony Reichhardt

Are rich nations up for drug reform? pp. 135-135

Erika Check

State's flu response raises concern pp. 139-139

Jacqueline Ruttimann

Unfinished symphony pp. 143-145

Jane Qiu

On thin ice pp. 146-147

Quirin Schiermeier

Challengers in the field pp. 149-149

Colin Macilwain

Medical council funds both clinical and basic research pp. 150-150

Colin Blakemore

Exaggerating one's success is rife in Chinese academia pp. 150-150

Zheng Huang

Allergy test might have avoided drug-trial disaster pp. 150-150

John H. Weis

Keeping an eye on privacy issues with geospatial data pp. 150-150

Andrew Curtis, Jacqueline W. Mills and Michael Leitner

Evolution of the selfish gene pp. 151-152

Dan Sperber

Renaissance magic and mysticism pp. 152-153

Rina Knoeff

The soldier's tale pp. 153-153

Matt Ridley

Human frailties pp. 155-155

Ian Tattersall

Science's secret service pp. 156-157

Daniel S. Greenberg

A journey to remember pp. 157-159

Yadin Dudai

The ant trail pp. 159-159

Laurent Keller

A cross-cultural relationship pp. 160-160

Rebecca Goldstein

Engineering immune evasion pp. 161-161

John R. Mascola

Interplanetary kidnap pp. 162-163

Alessandro Morbidelli

Cracking the calcium entry code pp. 163-165

Anant B. Parekh

A catalytic knight's move pp. 165-166

Robert H. Crabtree

What does it mean to be just 17? pp. 166-167

Cristina M. Tato and John J. O'Shea

When a phase is born pp. 168-169

Pablo G. Debenedetti

Cause for a llama pp. 169-169

Richard Webb

The noble art of recycling pp. 169-170

Takuya Matsumoto

Diving insects boost their buoyancy bubbles pp. 171-171

Philip G. D. Matthews and Roger S. Seymour

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4 pp. 173-178

Mark Gilchrist, Vesteinn Thorsson, Bin Li, Alistair G. Rust, Martin Korb, Kathleen Kennedy, Tsonwin Hai, Hamid Bolouri and Alan Aderem

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function pp. 179-185

Stefan Feske, Yousang Gwack, Murali Prakriya, Sonal Srikanth, Sven-Holger Puppel, Bogdan Tanasa, Patrick G. Hogan, Richard S. Lewis, Mark Daly and Anjana Rao

Seawater subduction controls the heavy noble gas composition of the mantle pp. 186-191

Greg Holland and Chris J. Ballentine

Neptune's capture of its moon Triton in a binary–planet gravitational encounter pp. 192-194

Craig B. Agnor and Douglas P. Hamilton

Local switching of two-dimensional superconductivity using the ferroelectric field effect pp. 195-198

K. S. Takahashi, M. Gabay, D. Jaccard, K. Shibuya, T. Ohnishi, M. Lippmaa and J.-M. Triscone

Strained silicon as a new electro-optic material pp. 199-202

Rune S. Jacobsen, Karin N. Andersen, Peter I. Borel, Jacob Fage-Pedersen, Lars H. Frandsen, Ole Hansen, Martin Kristensen, Andrei V. Lavrinenko, Gaid Moulin, Haiyan Ou, Christophe Peucheret, Beáta Zsigri and Anders Bjarklev

Discovery of a 25-cm asteroid clast in the giant Morokweng impact crater, South Africa pp. 203-206

W. D. Maier, M. A. G. Andreoli, I. McDonald, M. D. Higgins, A. J. Boyce, A. Shukolyukov, G. W. Lugmair, L. D. Ashwal, P. Gräser, E. M. Ripley and R. J. Hart

New carbon dates link climatic change with human colonization and Pleistocene extinctions pp. 207-209

R. Dale Guthrie

Sympatric speciation in palms on an oceanic island pp. 210-213

Vincent Savolainen, Marie-Charlotte Anstett, Christian Lexer, Ian Hutton, James J. Clarkson, Maria V. Norup, Martyn P. Powell, David Springate, Nicolas Salamin and William J. Baker

Future fitness and helping in social queues pp. 214-217

Jeremy Field, Adam Cronin and Catherine Bridge

Specification of the neural crest occurs during gastrulation and requires Pax7 pp. 218-222

Martín L. Basch, Marianne Bronner-Fraser and Martín I. García-Castro

Neurons in the orbitofrontal cortex encode economic value pp. 223-226

Camillo Padoa-Schioppa and John A. Assad

A trehalose metabolic enzyme controls inflorescence architecture in maize pp. 227-230

Namiko Satoh-Nagasawa, Nobuhiro Nagasawa, Simon Malcomber, Hajime Sakai and David Jackson

Transforming growth factor-β induces development of the TH17 lineage pp. 231-234

Paul R. Mangan, Laurie E. Harrington, Darrell B. O'Quinn, Whitney S. Helms, Daniel C. Bullard, Charles O. Elson, Robin D. Hatton, Sharon M. Wahl, Trenton R. Schoeb and Casey T. Weaver

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells pp. 235-238

Estelle Bettelli, Yijun Carrier, Wenda Gao, Thomas Korn, Terry B. Strom, Mohamed Oukka, Howard L. Weiner and Vijay K. Kuchroo

Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity pp. 239-243

Diane M. Roberts, Anjali Nanda, Menzo J. E. Havenga, Peter Abbink, Diana M. Lynch, Bonnie A. Ewald, Jinyan Liu, Anna R. Thorner, Patricia E. Swanson, Darci A. Gorgone, Michelle A. Lifton, Angelique A. C. Lemckert, Lennart Holterman, Bing Chen, Athmanundh Dilraj, Angela Carville, Keith G. Mansfield, Jaap Goudsmit and Dan H. Barouch

A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting pp. 244-247

Olivier Namy, Stephen J. Moran, David I. Stuart, Robert J. C. Gilbert and Ian Brierley

Correction: Corrigendum: Lipid–protein interactions in double-layered two-dimensional AQP0 crystals pp. 248-248

Tamir Gonen, Yifan Cheng, Piotr Sliz, Yoko Hiroaki, Yoshinori Fujiyoshi, Stephen C. Harrison and Thomas Walz

Correction: Corrigendum: Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee pp. 248-248

Jennifer F. Hughes, Helen Skaletsky, Tatyana Pyntikova, Patrick J. Minx, Tina Graves, Steve Rozen, Richard K. Wilson and David C. Page

Correction: Corrigendum: An acidic protein aligns magnetosomes along a filamentous structure in magnetotactic bacteria pp. 248-248

André Scheffel, Manuela Gruska, Damien Faivre, Alexandros Linaroudis, Peter L. Graumann, Jürgen M. Plitzko and Dirk Schüler

Good in parts pp. 249-249

Paul Smaglik

Talk about toxic pp. 250-251

Ricki Lewis

Stephen Forrest, vice-president for research and William Gould Dow professor in electrical engineering, University of Michigan, Ann Arbor pp. 252-252

Virginia Gewin

What makes a good PhD student? pp. 252-252

Georgia Chenevix-Trench

Valuable diversions pp. 252-252

Katja Bargum

The aching of Dion Harper pp. 254-254

Arthur Chrenkoff

2006, volume 441, articles 7089

Comparing models of species abundance pp. E1-E1

Jérôme Chave, David Alonso and Rampal S. Etienne

Comparing models of species abundance (Reply) pp. E1-E2

Igor Volkov, Jayanth R. Banavar, Fangliang He, Stephen P. Hubbell and Amos Maritan

US posts sensitive climate report for public comment pp. 6-7

Jim Giles

Tempers flare at hurricane meeting pp. 11-11

Alexandra Witze

Chemists get out begging bowl to avert closure pp. 12-13

Mark Peplow

Facing the opposition pp. 17-19

Erika Check

It's a postdoc's life pp. 20-21

Jacqueline Ruttimann

Market watch pp. 23-23

Colin Macilwain

Computing: report leaps geographical barriers but stumbles over gender pp. 25-25

Martha E. Pollack, Susanne E. Hambrusch, Carla Schlatter Ellis, Barbara J. Grosz, Jessica Hodgins, Ruzena Bajcsy, Carla E. Brodley, Luigia Carlucci Aiello, Maria Paola Bonacina, Lori A. Clarke, Julia Hirschberg, Manuela M. Veloso, Nancy Amato, Liz Sonenberg, Elaine Weyuker, Lori Pollock, Mary Jane Irwin, Lin Padgham, Barbara G. Ryder, Tiziana Catarci, Kathleen F. McCoy, Maria Klawe, Sandra Carberry, Laura Dillon, Kathleen McKeown and Mary Lou Soffa

Computer ‘recycling’ builds garbage dumps overseas pp. 25-25

G. Agoramoorthy

A logical alternative for biological computing pp. 25-25

Derek Partridge

Colossus was the first electronic digital computer pp. 25-25

Jürgen Schmidhuber

A Palaeozoic whodunnit pp. 27-27

Michael Benton

A martian mystery pp. 28-29

John F. Kerridge

The source of the problem pp. 28-28

Ganesh Pangare

A search for meaning pp. 29-30

Daniel Nettle

Science in culture: A sense of civic beauty pp. 30-30

Martin Kemp

The first axion? pp. 31-32

Steve Lamoreaux

Divining cancer cell weaknesses pp. 32-34

William G. Kaelin

A new spin on Saturn pp. 34-35

David J. Stevenson

Chromosome guardians on duty pp. 35-37

Paul Megee

Polymers show they're metal pp. 37-37

Richard Friend

Complex call production in the túngara frog pp. 38-38

M. Gridi-Papp, A. S. Rand and M. J. Ryan

The search for signs of recovery of the ozone layer pp. 39-45

Elizabeth C. Weatherhead and Signe Bech Andersen

Shugoshin collaborates with protein phosphatase 2A to protect cohesin pp. 46-52

Tomoya S. Kitajima, Takeshi Sakuno, Kei-ichiro Ishiguro, Shun-ichiro Iemura, Tohru Natsume, Shigehiro A. Kawashima and Yoshinori Watanabe

Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I pp. 53-61

Christian G. Riedel, Vittorio L. Katis, Yuki Katou, Saori Mori, Takehiko Itoh, Wolfgang Helmhart, Marta Gálová, Mark Petronczki, Juraj Gregan, Bulent Cetin, Ingrid Mudrak, Egon Ogris, Karl Mechtler, Laurence Pelletier, Frank Buchholz, Katsuhiko Shirahige and Kim Nasmyth

A regular period for Saturn's magnetic field that may track its internal rotation pp. 62-64

G. Giampieri, M. K. Dougherty, E. J. Smith and C. T. Russell

Metallic transport in polyaniline pp. 65-68

Kwanghee Lee, Shinuk Cho, Sung Heum Park, A. J. Heeger, Chan-Woo Lee and Suck-Hyun Lee

Towards molecular electronics with large-area molecular junctions pp. 69-72

Hylke B. Akkerman, Paul W. M. Blom, Dago M. de Leeuw and Bert de Boer

Weakening of tropical Pacific atmospheric circulation due to anthropogenic forcing pp. 73-76

Gabriel A. Vecchi, Brian J. Soden, Andrew T. Wittenberg, Isaac M. Held, Ants Leetmaa and Matthew J. Harrison

A primitive fish provides key characters bearing on deep osteichthyan phylogeny pp. 77-80

Min Zhu, Xiaobo Yu, Wei Wang, Wenjin Zhao and Liantao Jia

Climate change and population declines in a long-distance migratory bird pp. 81-83

Christiaan Both, Sandra Bouwhuis, C. M. Lessells and Marcel E. Visser

Testing the genetics underlying the co-evolution of mate choice and ornament in the wild pp. 84-86

Anna Qvarnström, Jon E. Brommer and Lars Gustafsson

A distal enhancer and an ultraconserved exon are derived from a novel retroposon pp. 87-90

Gill Bejerano, Craig B. Lowe, Nadav Ahituv, Bryan King, Adam Siepel, Sofie R. Salama, Edward M. Rubin, W. James Kent and David Haussler

A small-molecule screen in C. elegans yields a new calcium channel antagonist pp. 91-95

Trevor C. Y. Kwok, Nicole Ricker, Regina Fraser, Allen W. Chan, Andrew Burns, Elise F. Stanley, Peter McCourt, Sean R. Cutler and Peter J. Roy

Downstream nuclear events in brassinosteroid signalling pp. 96-100

Grégory Vert and Joanne Chory

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses pp. 101-105

Hiroki Kato, Osamu Takeuchi, Shintaro Sato, Mitsutoshi Yoneyama, Masahiro Yamamoto, Kosuke Matsui, Satoshi Uematsu, Andreas Jung, Taro Kawai, Ken J. Ishii, Osamu Yamaguchi, Kinya Otsu, Tohru Tsujimura, Chang-Sung Koh, Caetano Reis e Sousa, Yoshiharu Matsuura, Takashi Fujita and Shizuo Akira

A loss-of-function RNA interference screen for molecular targets in cancer pp. 106-110

Vu N. Ngo, R. Eric Davis, Laurence Lamy, Xin Yu, Hong Zhao, Georg Lenz, Lloyd T. Lam, Sandeep Dave, Liming Yang, John Powell and Louis M. Staudt

RNAi-mediated gene silencing in non-human primates pp. 111-114

Tracy S. Zimmermann, Amy C. H. Lee, Akin Akinc, Birgit Bramlage, David Bumcrot, Matthew N. Fedoruk, Jens Harborth, James A. Heyes, Lloyd B. Jeffs, Matthias John, Adam D. Judge, Kieu Lam, Kevin McClintock, Lubomir V. Nechev, Lorne R. Palmer, Timothy Racie, Ingo Röhl, Stephan Seiffert, Sumi Shanmugam, Vandana Sood, Jürgen Soutschek, Ivanka Toudjarska, Amanda J. Wheat, Ed Yaworski, William Zedalis, Victor Koteliansky, Muthiah Manoharan, Hans-Peter Vornlocher and Ian MacLachlan

The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends pp. 115-119

Jonne Helenius, Gary Brouhard, Yannis Kalaidzidis, Stefan Diez and Jonathon Howard

Correction: Corrigendum: Genome sequencing in microfabricated high-density picolitre reactors pp. 120-120

Marcel Margulies, Michael Egholm, William E. Altman, Said Attiya, Joel S. Bader, Lisa A. Bemben, Jan Berka, Michael S. Braverman, Yi-Ju Chen, Zhoutao Chen, Scott B. Dewell, Alex de Winter, James Drake, Lei Du, Joseph M. Fierro, Robin Forte, Xavier V. Gomes, Brian C. Godwin, Wen He, Scott Helgesen, Chun Heen Ho, Stephen K. Hutchison, Gerard P. Irzyk, Szilveszter C. Jando, Maria L. I. Alenquer, Thomas P. Jarvie, Kshama B. Jirage, Jong-Bum Kim, James R. Knight, Janna R. Lanza, John H. Leamon, William L. Lee, Steven M. Lefkowitz, Ming Lei, Jing Li, Kenton L. Lohman, Hong Lu, Vinod B. Makhijani, Keith E. McDade, Michael P. McKenna, Eugene W. Myers, Elizabeth Nickerson, John R. Nobile, Ramona Plant, Bernard P. Puc, Michael Reifler, Michael T. Ronan, George T. Roth, Gary J. Sarkis, Jan Fredrik Simons, John W. Simpson, Maithreyan Srinivasan, Karrie R. Tartaro, Alexander Tomasz, Kari A. Vogt, Greg A. Volkmer, Shally H. Wang, Yong Wang, Michael P. Weiner, David A. Willoughby, Pengguang Yu, Richard F. Begley and Jonathan M. Rothberg

Correction: Corrigendum: A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery pp. 120-120

Michael-Christopher Keogh, Jung-Ae Kim, Michael Downey, Jeffrey Fillingham, Dipanjan Chowdhury, Jacob C. Harrison, Megumi Onishi, Nira Datta, Sarah Galicia, Andrew Emili, Judy Lieberman, Xuetong Shen, Stephen Buratowski, James E. Haber, Daniel Durocher, Jack F. Greenblatt and Nevan J. Krogan

Correction: Corrigendum: A high-mobility electron gas at the LaAlO3/SrTiO3 heterointerface pp. 120-120

A. Ohtomo and H. Y. Hwang

Erratum: Significant primordial star formation at redshifts z ≈ 3–4 pp. 120-120

Raul Jimenez and Zoltan Haiman

Thinking big pp. 121-121

Paul Smaglik

Misconduct mayhem pp. 122-123

Kendall Powell

William Harris, president and chief executive, Science Foundation Arizona pp. 124-124

Virginia Gewin

Postdoc prep pp. 124-124

Jabbar Bennett

On Mozart's wavelength pp. 124-124

Andreas Andersson

Taking good care of myself pp. 126-126

Ian R. MacLeod