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2021, volume 589, articles 7843

Publisher Correction: Impacts of speciation and extinction measured by an evolutionary decay clock pp. E10-E10

Jennifer F. Hoyal Cuthill, Nicholas Guttenberg and Graham E. Budd

Heed blame for extreme weather pp. 493-493

Richard A. Betts

Why did the world’s pandemic warning system fail when COVID hit? pp. 499-500

Amy Maxmen

Fast-spreading COVID variant can elude immune responses pp. 500-501

Ewen Callaway

‘Inspired choice’: Biden appoints sociologist Alondra Nelson to top science post pp. 502-502

Nidhi Subbaraman

What new COVID variants mean for schools is not yet clear pp. 503-503

Dyani Lewis

Are COVID vaccination programmes working? Scientists seek first clues pp. 504-505

Smriti Mallapaty

Science family of journals announces change to open-access policy pp. 505-505

Richard Van Noorden

How ecstasy and psilocybin are shaking up psychiatry pp. 506-509

Paul Tullis

Meteorites: ‘a story written across light years down the barrel of a microscope’ pp. 510-511

Meenakshi Wadhwa

Akito Arima (1930–2020) pp. 513-513

David Swinbanks

Cancer research needs a better map pp. 514-516

Jesse S. Boehm, Mathew J. Garnett, David J. Adams, Hayley E. Francies, Todd R. Golub, William C. Hahn, Francesco Iorio, James M. McFarland, Leopold Parts and Francisca Vazquez

RETRACTED ARTICLE: A two-pronged attack on antibiotic-resistant microbes pp. 517-518

Youcef Mehellou and Benjamin E. Willcox

Helium nucleus measured with record precision pp. 518-519

Wilfried Nörtershäuser

Pain-sensing neurons mobilize blood stem cells from bone marrow pp. 520-521

Anastasia N. Tikhonova and Iannis Aifantis

Palaeoclimate puzzle explained by seasonal variation pp. 521-522

Jennifer Hertzberg

Base editor repairs mutation found in the premature-ageing syndrome progeria pp. 522-524

Wilbert P. Vermeij and Jan H. J. Hoeijmakers

Accurate machine learning in materials science facilitated by using diverse data sources pp. 524-525

Rohit Batra

Measuring the α-particle charge radius with muonic helium-4 ions pp. 527-531

Julian J. Krauth, Karsten Schuhmann, Marwan Abdou Ahmed, Fernando D. Amaro, Pedro Amaro, François Biraben, Tzu-Ling Chen, Daniel S. Covita, Andreas J. Dax, Marc Diepold, Luis M. P. Fernandes, Beatrice Franke, Sandrine Galtier, Andrea L. Gouvea, Johannes Götzfried, Thomas Graf, Theodor W. Hänsch, Jens Hartmann, Malte Hildebrandt, Paul Indelicato, Lucile Julien, Klaus Kirch, Andreas Knecht, Yi-Wei Liu, Jorge Machado, Cristina M. B. Monteiro, Françoise Mulhauser, Boris Naar, Tobias Nebel, François Nez, Joaquim M. F. Santos, José Paulo Santos, Csilla I. Szabo, David Taqqu, João F. C. A. Veloso, Jan Vogelsang, Andreas Voss, Birgit Weichelt, Randolf Pohl, Aldo Antognini and Franz Kottmann

Metastability of diamond ramp-compressed to 2 terapascals pp. 532-535

A. Lazicki, D. McGonegle, J. R. Rygg, D. G. Braun, D. C. Swift, M. G. Gorman, R. F. Smith, P. G. Heighway, A. Higginbotham, M. J. Suggit, D. E. Fratanduono, F. Coppari, C. E. Wehrenberg, R. G. Kraus, D. Erskine, J. V. Bernier, J. M. McNaney, R. E. Rudd, G. W. Collins, J. H. Eggert and J. S. Wark

Correlation-driven topological phases in magic-angle twisted bilayer graphene pp. 536-541

Youngjoon Choi, Hyunjin Kim, Yang Peng, Alex Thomson, Cyprian Lewandowski, Robert Polski, Yiran Zhang, Harpreet Singh Arora, Kenji Watanabe, Takashi Taniguchi, Jason Alicea and Stevan Nadj-Perge

Metallaphotoredox aryl and alkyl radiomethylation for PET ligand discovery pp. 542-547

Robert W. Pipal, Kenneth T. Stout, Patricia Z. Musacchio, Sumei Ren, Thomas J. A. Graham, Stefan Verhoog, Liza Gantert, Talakad G. Lohith, Alexander Schmitz, Hsiaoju S. Lee, David Hesk, Eric D. Hostetler, Ian W. Davies and David W. C. MacMillan

Seasonal origin of the thermal maxima at the Holocene and the last interglacial pp. 548-553

Samantha Bova, Yair Rosenthal, Zhengyu Liu, Shital P. Godad and Mi Yan

Global and regional drivers of land-use emissions in 1961–2017 pp. 554-561

Chaopeng Hong, Jennifer A. Burney, Julia Pongratz, Julia E. M. S. Nabel, Nathaniel D. Mueller, Robert B. Jackson and Steven J. Davis

A thin mantle transition zone beneath the equatorial Mid-Atlantic Ridge pp. 562-566

Matthew R. Agius, Catherine A. Rychert, Nicholas Harmon, Saikiran Tharimena and J.-Michael Kendall

Half a century of global decline in oceanic sharks and rays pp. 567-571

Nathan Pacoureau, Cassandra L. Rigby, Peter M. Kyne, Richard B. Sherley, Henning Winker, John K. Carlson, Sonja V. Fordham, Rodrigo Barreto, Daniel Fernando, Malcolm P. Francis, Rima W. Jabado, Katelyn B. Herman, Kwang-Ming Liu, Andrea D. Marshall, Riley A. Pollom, Evgeny V. Romanov, Colin A. Simpfendorfer, Jamie S. Yin, Holly K. Kindsvater and Nicholas K. Dulvy

Monitoring hiring discrimination through online recruitment platforms pp. 572-576

Dominik Hangartner, Daniel Kopp and Michael Siegenthaler

Neural circuit mechanisms of sexual receptivity in Drosophila females pp. 577-581

Kaiyu Wang, Fei Wang, Nora Forknall, Tansy Yang, Christopher Patrick, Ruchi Parekh and Barry J. Dickson

Availability of food determines the need for sleep in memory consolidation pp. 582-585

Nitin S. Chouhan, Leslie C. Griffith, Paula Haynes and Amita Sehgal

An SHR–SCR module specifies legume cortical cell fate to enable nodulation pp. 586-590

Wentao Dong, Yayun Zhu, Huizhong Chang, Chunhua Wang, Jun Yang, Jincai Shi, Jinpeng Gao, Weibing Yang, Liying Lan, Yuru Wang, Xiaowei Zhang, Huiling Dai, Yuchen Miao, Lin Xu, Zuhua He, Chunpeng Song, Shuang Wu, Dong Wang, Nan Yu and Ertao Wang

Nociceptive nerves regulate haematopoietic stem cell mobilization pp. 591-596

Xin Gao, Dachuan Zhang, Chunliang Xu, Huihui Li, Kathleen M. Caron and Paul S. Frenette

RETRACTED ARTICLE: IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance pp. 597-602

Kumar Sachin Singh, Rishabh Sharma, Poli Adi Narayana Reddy, Prashanthi Vonteddu, Madeline Good, Anjana Sundarrajan, Hyeree Choi, Kar Muthumani, Andrew Kossenkov, Aaron R. Goldman, Hsin-Yao Tang, Maxim Totrov, Joel Cassel, Maureen E. Murphy, Rajasekharan Somasundaram, Meenhard Herlyn, Joseph M. Salvino and Farokh Dotiwala

COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice pp. 603-607

Jian Zheng, Lok-Yin Roy Wong, Kun Li, Abhishek Kumar Verma, Miguel E. Ortiz, Christine Wohlford-Lenane, Mariah R. Leidinger, C. Michael Knudson, David K. Meyerholz, Paul B. McCray and Stanley Perlman

In vivo base editing rescues Hutchinson–Gilford progeria syndrome in mice pp. 608-614

Luke W. Koblan, Michael R. Erdos, Christopher Wilson, Wayne A. Cabral, Jonathan M. Levy, Zheng-Mei Xiong, Urraca L. Tavarez, Lindsay M. Davison, Yantenew G. Gete, Xiaojing Mao, Gregory A. Newby, Sean P. Doherty, Narisu Narisu, Quanhu Sheng, Chad Krilow, Charles Y. Lin, Leslie B. Gordon, Kan Cao, Francis S. Collins, Jonathan D. Brown and David R. Liu

Capping pores of alphavirus nsP1 gate membranous viral replication factories pp. 615-619

Rhian Jones, Gabriel Bragagnolo, Rocío Arranz and Juan Reguera

Structures of the glucocorticoid-bound adhesion receptor GPR97–Go complex pp. 620-626

Yu-Qi Ping, Chunyou Mao, Peng Xiao, Ru-Jia Zhao, Yi Jiang, Zhao Yang, Wen-Tao An, Dan-Dan Shen, Fan Yang, Huibing Zhang, Changxiu Qu, Qingya Shen, Caiping Tian, Zi-jian Li, Shaolong Li, Guang-Yu Wang, Xiaona Tao, Xin Wen, Ya-Ni Zhong, Jing Yang, Fan Yi, Xiao Yu, H. Eric Xu, Yan Zhang and Jin-Peng Sun

Let the dog in: how institutions and colleagues can help scientists who require support animals pp. 627-629

Nina Notman

Seven technologies to watch in 2021 pp. 630-632

Esther Landhuis

The bird librarian pp. 634-634

James Mitchell Crow

2021, volume 589, articles 7842

Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development pp. E4-E4

David U. Gorkin, Iros Barozzi, Yuan Zhao, Yanxiao Zhang, Hui Huang, Ah Young Lee, Bin Li, Joshua Chiou, Andre Wildberg, Bo Ding, Bo Zhang, Mengchi Wang, J. Seth Strattan, Jean M. Davidson, Yunjiang Qiu, Veena Afzal, Jennifer A. Akiyama, Ingrid Plajzer-Frick, Catherine S. Novak, Momoe Kato, Tyler H. Garvin, Quan T. Pham, Anne N. Harrington, Brandon J. Mannion, Elizabeth A. Lee, Yoko Fukuda-Yuzawa, Yupeng He, Sebastian Preissl, Sora Chee, Jee Yun Han, Brian A. Williams, Diane Trout, Henry Amrhein, Hongbo Yang, J. Michael Cherry, Wei Wang, Kyle Gaulton, Joseph R. Ecker, Yin Shen, Diane E. Dickel, Axel Visel, Len A. Pennacchio and Bing Ren

Author Correction: A large-scale binding and functional map of human RNA-binding proteins pp. E5-E5

Eric L. Nostrand, Peter Freese, Gabriel A. Pratt, Xiaofeng Wang, Xintao Wei, Rui Xiao, Steven M. Blue, Jia-Yu Chen, Neal A. L. Cody, Daniel Dominguez, Sara Olson, Balaji Sundararaman, Lijun Zhan, Cassandra Bazile, Louis Philip Benoit Bouvrette, Julie Bergalet, Michael O. Duff, Keri E. Garcia, Chelsea Gelboin-Burkhart, Myles Hochman, Nicole J. Lambert, Hairi Li, Michael P. McGurk, Thai B. Nguyen, Tsultrim Palden, Ines Rabano, Shashank Sathe, Rebecca Stanton, Amanda Su, Ruth Wang, Brian A. Yee, Bing Zhou, Ashley L. Louie, Stefan Aigner, Xiang-Dong Fu, Eric Lécuyer, Christopher B. Burge, Brenton R. Graveley and Gene W. Yeo

Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung pp. E6-E6

Thomas M. Conlon, Gerrit John-Schuster, Danijela Heide, Dominik Pfister, Mareike Lehmann, Yan Hu, Zeynep Ertüz, Martin A. Lopez, Meshal Ansari, Maximilian Strunz, Christoph Mayr, Ilias Angelidis, Chiara Ciminieri, Rita Costa, Marlene Sophia Kohlhepp, Adrien Guillot, Gizem Günes, Aicha Jeridi, Maja C. Funk, Giorgi Beroshvili, Sandra Prokosch, Jenny Hetzer, Stijn E. Verleden, Hani Alsafadi, Michael Lindner, Gerald Burgstaller, Lore Becker, Martin Irmler, Michael Dudek, Jakob Janzen, Eric Goffin, Reinoud Gosens, Percy Knolle, Bernard Pirotte, Tobias Stoeger, Johannes Beckers, Darcy Wagner, Indrabahadur Singh, Fabian J. Theis, Martin Hrabé Angelis, Tracy O’Connor, Frank Tacke, Michael Boutros, Emmanuel Dejardin, Oliver Eickelberg, Herbert B. Schiller, Melanie Königshoff, Mathias Heikenwalder and Ali Önder Yildirim

Publisher Correction: A network of transcriptional repressors modulates auxin responses pp. E7-E7

Jekaterina Truskina, Jingyi Han, Elina Chrysanthou, Carlos S. Galvan-Ampudia, Stéphanie Lainé, Géraldine Brunoud, Julien Macé, Simon Bellows, Jonathan Legrand, Anne-Maarit Bågman, Margot E. Smit, Ondřej Smetana, Arnaud Stigliani, Silvana Porco, Malcolm J. Bennett, Ari Pekka Mähönen, François Parcy, Etienne Farcot, Francois Roudier, Siobhan M. Brady, Anthony Bishopp and Teva Vernoux

Publisher Correction: Key role of chemistry versus bias in electrocatalytic oxygen evolution pp. E8-E8

Hong Nhan Nong, Lorenz J. Falling, Arno Bergmann, Malte Klingenhof, Hoang Phi Tran, Camillo Spöri, Rik Mom, Janis Timoshenko, Guido Zichittella, Axel Knop-Gericke, Simone Piccinin, Javier Pérez-Ramírez, Beatriz Roldan Cuenya, Robert Schlögl, Peter Strasser, Detre Teschner and Travis E. Jones

Publisher Correction: Distinct hypothalamic control of same- and opposite-sex mounting behaviour in mice pp. E9-E9

Tomomi Karigo, Ann Kennedy, Bin Yang, Mengyu Liu, Derek Tai, Iman A. Wahle and David J. Anderson

What my retraction taught me pp. 331-331

Ben de Haas

Alarming COVID variants show vital role of genomic surveillance pp. 337-338

David Cyranoski

‘A bloody mess’: Confusion reigns over naming of new COVID variants pp. 339-339

Ewen Callaway

Search for better COVID vaccines confounded by existing rollouts pp. 340-341

Elie Dolgin

COVID’s toll on smell and taste: what scientists do and don’t know pp. 342-343

Michael Marshall

COVID curbed carbon emissions in 2020 — but not by much pp. 343-343

Jeff Tollefson

Ten computer codes that transformed science pp. 344-348

Jeffrey M. Perkel

Lessons from the Moonshot for fixing global problems pp. 349-350

Jayati Ghosh

The grisly trials that gave poison to prisoners pp. 350-351

Alison Abbott

More than 100 aquatic-science societies sound climate alarm pp. 352-352

Scott A. Bonar

Storytelling can be a powerful tool for science pp. 352-352

Joshua Ettinger, Friederike E. L. Otto and E. Lisa F. Schipper

Journals — women’s marital status is none of your business pp. 352-352

Anna Zychlinsky Scharff, Alexandra Jablonka and Christine Happle

Brain rhythms that help us to detect borders pp. 353-354

Hugo J. Spiers

Precise mapping reveals gaps in global measles vaccination coverage pp. 354-355

C. Edson Utazi and Andrew J. Tatem

Electrons broken into pieces at crystal defects pp. 356-357

Carmine Ortix

Anti-ageing effects of protein restriction unpacked pp. 357-358

Cristal M. Hill and Matt Kaeberlein

Psychedelics re-engineered for potential use in the clinic pp. 358-359

Gabriela Manzano-Nieves and Conor Liston

Mechanical memory written and read remotely pp. 360-361

Corentin Coulais

Lessons from the host defences of bats, a unique viral reservoir pp. 363-370

Aaron T. Irving, Matae Ahn, Geraldine Goh, Danielle E. Anderson and Lin-Fa Wang

Observation of the onset of a blue jet into the stratosphere pp. 371-375

Torsten Neubert, Olivier Chanrion, Matthias Heumesser, Krystallia Dimitriadou, Lasse Husbjerg, Ib Lundgaard Rasmussen, Nikolai Østgaard and Victor Reglero

Trapped fractional charges at bulk defects in topological insulators pp. 376-380

Christopher W. Peterson, Tianhe Li, Wentao Jiang, Taylor L. Hughes and Gaurav Bahl

Bulk–disclination correspondence in topological crystalline insulators pp. 381-385

Yang Liu, Shuwai Leung, Fei-Fei Li, Zhi-Kang Lin, Xiufeng Tao, Yin Poo and Jian-Hua Jiang

A reprogrammable mechanical metamaterial with stable memory pp. 386-390

Tian Chen, Mark Pauly and Pedro M. Reis

Transporting and concentrating vibrational energy to promote isomerization pp. 391-395

Jascha A. Lau, Li Chen, Arnab Choudhury, Dirk Schwarzer, Varun B. Verma and Alec M. Wodtke

A stable low-temperature H2-production catalyst by crowding Pt on α-MoC pp. 396-401

Xiao Zhang, Mengtao Zhang, Yuchen Deng, Mingquan Xu, Luca Artiglia, Wen Wen, Rui Gao, Bingbing Chen, Siyu Yao, Xiaochen Zhang, Mi Peng, Jie Yan, Aowen Li, Zheng Jiang, Xingyu Gao, Sufeng Cao, Ce Yang, A. Jeremy Kropf, Jinan Shi, Jinglin Xie, Mingshu Bi, Jeroen A. Bokhoven, Yong-Wang Li, Xiaodong Wen, Maria Flytzani-Stephanopoulos, Chuan Shi, Wu Zhou and Ding Ma

Lake heatwaves under climate change pp. 402-407

R. Iestyn Woolway, Eleanor Jennings, Tom Shatwell, Malgorzata Golub, Don C. Pierson and Stephen C. Maberly

High sensitivity of tropical precipitation to local sea surface temperature pp. 408-414

Peter Good, Robin Chadwick, Christopher E. Holloway, John Kennedy, Jason A. Lowe, Romain Roehrig and Stephanie S. Rushley

Boundary-anchored neural mechanisms of location-encoding for self and others pp. 420-425

Matthias Stangl, Uros Topalovic, Cory S. Inman, Sonja Hiller, Diane Villaroman, Zahra M. Aghajan, Leonardo Christov-Moore, Nicholas R. Hasulak, Vikram R. Rao, Casey H. Halpern, Dawn Eliashiv, Itzhak Fried and Nanthia Suthana

A brainstem peptide system activated at birth protects postnatal breathing pp. 426-430

Yingtang Shi, Daniel S. Stornetta, Robert J. Reklow, Alisha Sahu, Yvonne Wabara, Ashley Nguyen, Keyong Li, Yong Zhang, Edward Perez-Reyes, Rachel A. Ross, Bradford B. Lowell, Ruth L. Stornetta, Gregory D. Funk, Patrice G. Guyenet and Douglas A. Bayliss

Pairing of segmentation clock genes drives robust pattern formation pp. 431-436

Oriana Q. H. Zinani, Kemal Keseroğlu, Ahmet Ay and Ertuğrul M. Özbudak

Arterialization requires the timely suppression of cell growth pp. 437-441

Wen Luo, Irene Garcia-Gonzalez, Macarena Fernández-Chacón, Verónica Casquero-Garcia, Maria S. Sanchez-Muñoz, Severin Mühleder, Lourdes Garcia-Ortega, Jorge Andrade, Michael Potente and Rui Benedito

RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy pp. 442-447

Magdalena Paolino, Rubina Koglgruber, Shane J. F. Cronin, Iris Uribesalgo, Esther Rauscher, Jürgen Harreiter, Michael Schuster, Dagmar Bancher-Todesca, Blanka Pranjic, Maria Novatchkova, Juan P. Fededa, Andrea J. White, Verena Sigl, Sabine Dekan, Thomas Penz, Christoph Bock, Lukas Kenner, Georg A. Holländer, Graham Anderson, Alexandra Kautzky-Willer and Josef M. Penninger

Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis pp. 448-455

Ievgenia Pastushenko, Federico Mauri, Yura Song, Florian Cock, Bob Meeusen, Benjamin Swedlund, Francis Impens, Delphi Haver, Matthieu Opitz, Manuel Thery, Yacine Bareche, Gaelle Lapouge, Marjorie Vermeersch, Yves-Rémi Eycke, Cédric Balsat, Christine Decaestecker, Youri Sokolow, Sergio Hassid, Alicia Perez-Bustillo, Beatriz Agreda-Moreno, Luis Rios-Buceta, Pedro Jaen, Pedro Redondo, Ramon Sieira-Gil, Jose F. Millan-Cayetano, Onofre Sanmatrtin, Nicky D’Haene, Virginie Moers, Milena Rozzi, Jeremy Blondeau, Sophie Lemaire, Samuel Scozzaro, Veerle Janssens, Magdalena Troya, Christine Dubois, David Pérez-Morga, Isabelle Salmon, Christos Sotiriou, Francoise Helmbacher and Cédric Blanpain

Sorting nexin 5 mediates virus-induced autophagy and immunity pp. 456-461

Xiaonan Dong, Yuting Yang, Zhongju Zou, Yuting Zhao, Bo Ci, Lin Zhong, Madhura Bhave, Liwei Wang, Yi-Chun Kuo, Xiao Zang, Rui Zhong, Elizabeth R. Aguilera, R. Blake Richardson, Boris Simonetti, John W. Schoggins, Julie K. Pfeiffer, Li Yu, Xuewu Zhang, Yang Xie, Sandra L. Schmid, Guanghua Xiao, Paul A. Gleeson, Nicholas T. Ktistakis, Peter J. Cullen, Ramnik J. Xavier and Beth Levine

Measuring DNA mechanics on the genome scale pp. 462-467

Aakash Basu, Dmitriy G. Bobrovnikov, Zan Qureshi, Tunc Kayikcioglu, Thuy T. M. Ngo, Anand Ranjan, Sebastian Eustermann, Basilio Cieza, Michael T. Morgan, Miroslav Hejna, H. Tomas Rube, Karl-Peter Hopfner, Cynthia Wolberger, Jun S. Song and Taekjip Ha

Design of biologically active binary protein 2D materials pp. 468-473

Ariel J. Ben-Sasson, Joseph L. Watson, William Sheffler, Matthew Camp Johnson, Alice Bittleston, Logeshwaran Somasundaram, Justin Decarreau, Fang Jiao, Jiajun Chen, Ioanna Mela, Andrew A. Drabek, Sanchez M. Jarrett, Stephen C. Blacklow, Clemens F. Kaminski, Greg L. Hura, James J. Yoreo, Justin M. Kollman, Hannele Ruohola-Baker, Emmanuel Derivery and David Baker

A non-hallucinogenic psychedelic analogue with therapeutic potential pp. 474-479

Lindsay P. Cameron, Robert J. Tombari, Ju Lu, Alexander J. Pell, Zefan Q. Hurley, Yann Ehinger, Maxemiliano V. Vargas, Matthew N. McCarroll, Jack C. Taylor, Douglas Myers-Turnbull, Taohui Liu, Bianca Yaghoobi, Lauren J. Laskowski, Emilie I. Anderson, Guoliang Zhang, Jayashri Viswanathan, Brandon M. Brown, Michelle Tjia, Lee E. Dunlap, Zachary T. Rabow, Oliver Fiehn, Heike Wulff, John D. McCorvy, Pamela J. Lein, David Kokel, Dorit Ron, Jamie Peters, Yi Zuo and David E. Olson

Award-winning mentors share their secrets pp. 481-482

Chris Woolston

Monitoring the snap, crackle and pop of the sea pp. 484-484

James Mitchell Crow

2021, volume 589, articles 7841

Author Correction: Molecular dissection of amyloid disaggregation by human HSP70 pp. E2-E2

Anne S. Wentink, Nadinath B. Nillegoda, Jennifer Feufel, Gabrielė Ubartaitė, Carolyn P. Schneider, Paolo Los Rios, Janosch Hennig, Alessandro Barducci and Bernd Bukau

Publisher Correction: Galactosaminogalactan activates the inflammasome to provide host protection pp. E3-E3

Benoit Briard, Thierry Fontaine, Parimal Samir, David E. Place, Laetitia Muszkieta, R. K. Subbarao Malireddi, Rajendra Karki, Shelbi Christgen, Perrine Bomme, Peter Vogel, Rémi Beau, Emilia Mellado, Oumaima Ibrahim-Granet, Bernard Henrissat, Ravi C. Kalathur, Cam Robinson, Jean-Paul Latgé and Thirumala-Devi Kanneganti

The pandemic has pushed citizen panels online pp. 171-171

Claudia Chwalisz

Could new COVID variants undermine vaccines? Labs scramble to find out pp. 177-178

Ewen Callaway

What the landmark Brexit deal means for science pp. 179-179

Elizabeth Gibney

Will increasing traffic to the Moon contaminate its precious ice? pp. 180-181

Alexandra Witze

How can countries stretch COVID vaccine supplies? Scientists are divided over dosing strategies pp. 182-182

Heidi Ledford

What the data say about border closures and COVID spread pp. 185-185

Smriti Mallapaty

The secret forces that squeeze and pull life into shape pp. 186-188

Amber Dance

How COVID unlocked the power of RNA vaccines pp. 189-191

Elie Dolgin

Sisters who kicked down the door of the US medical establishment pp. 192-193

Hannah Wunsch

Jack Steinberger (1921–2020) pp. 194-194

Christine Sutton

Tiny robots and sensors need tiny batteries — here’s how to do it pp. 195-197

Minshen Zhu and Oliver G. Schmidt

Decentralize the energy system so COVID does not slow clean energy pp. 198-198

Anupam Kumar

COVID-19: research on tech habits needs industry support pp. 198-198

Daniel L. King, Joël Billieux and Paul H. Delfabbro

Reshoring EU agriculture risks undermining SDGs pp. 198-198

Erik Meijaard, Douglas Sheil and Daniel Murdiyarso

Community power could boost confidence in vaccination programmes pp. 198-198

Renee C. Wurth and Herman Saksono

Cosmic electromagnetic bomb sheds light on the origins of γ-ray bursts pp. 199-200

Christopher Thompson

Repeat DNA expands our understanding of autism spectrum disorder pp. 200-202

Anthony J. Hannan

AI weighs in on debate about universal facial expressions pp. 202-203

Lisa Feldman Barrett

Giant photon avalanches observed in nanoparticles pp. 204-205

Andries Meijerink and Freddy T. Rabouw

Rapid spectral variability of a giant flare from a magnetar in NGC 253 pp. 207-210

O. J. Roberts, P. Veres, M. G. Baring, M. S. Briggs, C. Kouveliotou, E. Bissaldi, G. Younes, S. I. Chastain, J. J. DeLaunay, D. Huppenkothen, A. Tohuvavohu, P. N. Bhat, E. Göğüş, A. J. Horst, J. A. Kennea, D. Kocevski, J. D. Linford, S. Guiriec, R. Hamburg, C. A. Wilson-Hodge and E. Burns

A bright γ-ray flare interpreted as a giant magnetar flare in NGC 253 pp. 211-213

D. Svinkin, D. Frederiks, K. Hurley, R. Aptekar, S. Golenetskii, A. Lysenko, A. V. Ridnaia, A. Tsvetkova, M. Ulanov, T. L. Cline, I. Mitrofanov, D. Golovin, A. Kozyrev, M. Litvak, A. Sanin, A. Goldstein, M. S. Briggs, C. Wilson-Hodge, A. Kienlin, X.-L. Zhang, A. Rau, V. Savchenko, E. Bozzo, C. Ferrigno, P. Ubertini, A. Bazzano, J. C. Rodi, S. Barthelmy, J. Cummings, H. Krimm, D. M. Palmer, W. Boynton, C. W. Fellows, K. P. Harshman, H. Enos and R. Starr

An integrated space-to-ground quantum communication network over 4,600 kilometres pp. 214-219

Yu-Ao Chen, Qiang Zhang, Teng-Yun Chen, Wen-Qi Cai, Sheng-Kai Liao, Jun Zhang, Kai Chen, Juan Yin, Ji-Gang Ren, Zhu Chen, Sheng-Long Han, Qing Yu, Ken Liang, Fei Zhou, Xiao Yuan, Mei-Sheng Zhao, Tian-Yin Wang, Xiao Jiang, Liang Zhang, Wei-Yue Liu, Yang Li, Qi Shen, Yuan Cao, Chao-Yang Lu, Rong Shu, Jian-Yu Wang, Li Li, Nai-Le Liu, Feihu Xu, Xiang-Bin Wang, Cheng-Zhi Peng and Jian-Wei Pan

Entangling logical qubits with lattice surgery pp. 220-224

Alexander Erhard, Hendrik Poulsen Nautrup, Michael Meth, Lukas Postler, Roman Stricker, Martin Stadler, Vlad Negnevitsky, Martin Ringbauer, Philipp Schindler, Hans J. Briegel, Rainer Blatt, Nicolai Friis and Thomas Monz

Landau quantization and highly mobile fermions in an insulator pp. 225-229

Pengjie Wang, Guo Yu, Yanyu Jia, Michael Onyszczak, F. Alexandre Cevallos, Shiming Lei, Sebastian Klemenz, Kenji Watanabe, Takashi Taniguchi, Robert J. Cava, Leslie M. Schoop and Sanfeng Wu

Giant nonlinear optical responses from photon-avalanching nanoparticles pp. 230-235

Changhwan Lee, Emma Z. Xu, Yawei Liu, Ayelet Teitelboim, Kaiyuan Yao, Angel Fernandez-Bravo, Agata M. Kotulska, Sang Hwan Nam, Yung Doug Suh, Artur Bednarkiewicz, Bruce E. Cohen, Emory M. Chan and P. James Schuck

Antarctic icebergs reorganize ocean circulation during Pleistocene glacials pp. 236-241

Aidan Starr, Ian R. Hall, Stephen Barker, Thomas Rackow, Xu Zhang, Sidney R. Hemming, H. J. L. van der Lubbe, Gregor Knorr, Melissa A. Berke, Grant R. Bigg, Alejandra Cartagena-Sierra, Francisco J. Jiménez-Espejo, Xun Gong, Jens Gruetzner, Nambiyathodi Lathika, Leah J. LeVay, Rebecca S. Robinson and Martin Ziegler

Functional adaptive landscapes predict terrestrial capacity at the origin of limbs pp. 242-245

Blake V. Dickson, Jennifer A. Clack, Timothy R. Smithson and Stephanie E. Pierce

Patterns of de novo tandem repeat mutations and their role in autism pp. 246-250

Ileena Mitra, Bonnie Huang, Nima Mousavi, Nichole Ma, Michael Lamkin, Richard Yanicky, Sharona Shleizer-Burko, Kirk E. Lohmueller and Melissa Gymrek

Sixteen facial expressions occur in similar contexts worldwide pp. 251-257

Alan S. Cowen, Dacher Keltner, Florian Schroff, Brendan Jou, Hartwig Adam and Gautam Prasad

Distinct hypothalamic control of same- and opposite-sex mounting behaviour in mice pp. 258-263

Tomomi Karigo, Ann Kennedy, Bin Yang, Mengyu Liu, Derek Tai, Iman A. Wahle and David J. Anderson

Reconstitution of the oocyte transcriptional network with transcription factors pp. 264-269

Nobuhiko Hamazaki, Hirohisa Kyogoku, Hiromitsu Araki, Fumihito Miura, Chisako Horikawa, Norio Hamada, So Shimamoto, Orie Hikabe, Kinichi Nakashima, Tomoya S. Kitajima, Takashi Ito, Harry G. Leitch and Katsuhiko Hayashi

Identification of SARS-CoV-2 inhibitors using lung and colonic organoids pp. 270-275

Yuling Han, Xiaohua Duan, Liuliu Yang, Benjamin E. Nilsson-Payant, Pengfei Wang, Fuyu Duan, Xuming Tang, Tomer M. Yaron, Tuo Zhang, Skyler Uhl, Yaron Bram, Chanel Richardson, Jiajun Zhu, Zeping Zhao, David Redmond, Sean Houghton, Duc-Huy T. Nguyen, Dong Xu, Xing Wang, Jose Jessurun, Alain Borczuk, Yaoxing Huang, Jared L. Johnson, Yuru Liu, Jenny Xiang, Hui Wang, Lewis C. Cantley, Benjamin R. tenOever, David D. Ho, Fong Cheng Pan, Todd Evans, Huanhuan Joyce Chen, Robert E. Schwartz and Shuibing Chen

A pooled testing strategy for identifying SARS-CoV-2 at low prevalence pp. 276-280

Leon Mutesa, Pacifique Ndishimye, Yvan Butera, Jacob Souopgui, Annette Uwineza, Robert Rutayisire, Ella Larissa Ndoricimpaye, Emile Musoni, Nadine Rujeni, Thierry Nyatanyi, Edouard Ntagwabira, Muhammed Semakula, Clarisse Musanabaganwa, Daniel Nyamwasa, Maurice Ndashimye, Eva Ujeneza, Ivan Emile Mwikarago, Claude Mambo Muvunyi, Jean Baptiste Mazarati, Sabin Nsanzimana, Neil Turok and Wilfred Ndifon

Decoding myofibroblast origins in human kidney fibrosis pp. 281-286

Christoph Kuppe, Mahmoud M. Ibrahim, Jennifer Kranz, Xiaoting Zhang, Susanne Ziegler, Javier Perales-Patón, Jitske Jansen, Katharina C. Reimer, James R. Smith, Ross Dobie, John R. Wilson-Kanamori, Maurice Halder, Yaoxian Xu, Nazanin Kabgani, Nadine Kaesler, Martin Klaus, Lukas Gernhold, Victor G. Puelles, Tobias B. Huber, Peter Boor, Sylvia Menzel, Remco M. Hoogenboezem, Eric M. J. Bindels, Joachim Steffens, Jürgen Floege, Rebekka K. Schneider, Julio Saez-Rodriguez, Neil C. Henderson and Rafael Kramann

ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies pp. 287-292

Cristina Lorenzo, Pilar Delgado, Christian E. Busse, Alejandro Sanz-Bravo, Inmaculada Martos-Folgado, Elena Bonzon-Kulichenko, Alessia Ferrarini, Ileana B. Gonzalez-Valdes, Sonia M. Mur, Raquel Roldán-Montero, Diego Martinez-Lopez, Jose L. Martin-Ventura, Jesús Vázquez, Hedda Wardemann and Almudena R. Ramiro

H1 histones control the epigenetic landscape by local chromatin compaction pp. 293-298

Michael A. Willcockson, Sean E. Healton, Cary N. Weiss, Boris A. Bartholdy, Yair Botbol, Laxmi N. Mishra, Dhruv S. Sidhwani, Tommy J. Wilson, Hugo B. Pinto, Maxim I. Maron, Karin A. Skalina, Laura Norwood Toro, Jie Zhao, Chul-Hwan Lee, Harry Hou, Nevin Yusufova, Cem Meydan, Adewola Osunsade, Yael David, Ethel Cesarman, Ari M. Melnick, Simone Sidoli, Benjamin A. Garcia, Winfried Edelmann, Fernando Macian and Arthur I. Skoultchi

Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture pp. 299-305

Nevin Yusufova, Andreas Kloetgen, Matt Teater, Adewola Osunsade, Jeannie M. Camarillo, Christopher R. Chin, Ashley S. Doane, Bryan J. Venters, Stephanie Portillo-Ledesma, Joseph Conway, Jude M. Phillip, Olivier Elemento, David W. Scott, Wendy Béguelin, Jonathan D. Licht, Neil L. Kelleher, Louis M. Staudt, Arthur I. Skoultchi, Michael-Christopher Keogh, Effie Apostolou, Christopher E. Mason, Marcin Imielinski, Tamar Schlick, Yael David, Aristotelis Tsirigos, C. David Allis, Alexey A. Soshnev, Ethel Cesarman and Ari M. Melnick

Structure and function of virion RNA polymerase of a crAss-like phage pp. 306-309

Arina V. Drobysheva, Sofia A. Panafidina, Matvei V. Kolesnik, Evgeny I. Klimuk, Leonid Minakhin, Maria V. Yakunina, Sergei Borukhov, Emelie Nilsson, Karin Holmfeldt, Natalya Yutin, Kira S. Makarova, Eugene V. Koonin, Konstantin V. Severinov, Petr G. Leiman and Maria L. Sokolova

Ultrafast structural changes within a photosynthetic reaction centre pp. 310-314

Robert Dods, Petra Båth, Dmitry Morozov, Viktor Ahlberg Gagnér, David Arnlund, Hoi Ling Luk, Joachim Kübel, Michał Maj, Adams Vallejos, Cecilia Wickstrand, Robert Bosman, Kenneth R. Beyerlein, Garrett Nelson, Mengning Liang, Despina Milathianaki, Joseph Robinson, Rajiv Harimoorthy, Peter Berntsen, Erik Malmerberg, Linda Johansson, Rebecka Andersson, Sergio Carbajo, Elin Claesson, Chelsie E. Conrad, Peter Dahl, Greger Hammarin, Mark S. Hunter, Chufeng Li, Stella Lisova, Antoine Royant, Cecilia Safari, Amit Sharma, Garth J. Williams, Oleksandr Yefanov, Sebastian Westenhoff, Jan Davidsson, Daniel P. DePonte, Sébastien Boutet, Anton Barty, Gergely Katona, Gerrit Groenhof, Gisela Brändén and Richard Neutze

How to include Indigenous researchers and their knowledge pp. 315-317

Virginia Gewin

Sharper signals: how machine learning is cleaning up microscopy images pp. 318-319

Amber Dance

‘I was no longer pretending or hiding’: a trans scientist finds a lab to call home pp. 322-322

Josie Glausiusz

2021, volume 589, articles 7840

Publisher Correction: Subducting carbon pp. E1-E1

Terry Plank and Craig E. Manning

Beyond past due: data to guide US school reopenings pp. 8-8

Emily Oster

Is lightning striking the Arctic more than ever before? pp. 11-12

Alexandra Witze

Prestigious AI meeting takes steps to improve ethics of research pp. 12-13

Davide Castelvecchi

Surprise! First peek inside Mars reveals a crust with cake-like layers pp. 13-13

Alexandra Witze

The science events to watch for in 2021 pp. 14-15

Holly Else

The lightning-fast quest for COVID vaccines — and what it means for other diseases pp. 16-18

Philip Ball

Africa’s reforestation: European Union and United States should step up pp. 19-19

David Gurwitz

Europe’s ‘green deal’ and carbon dioxide removal pp. 19-19

David Reiner, Ilkka Hannula, Tiina Koljonen, Myles Allen, Wolfgang Lucht, Gonzalo Guillén-Gosálbez and Niall Mac Dowell

Optimizing public services after COVID pp. 19-19

Jonathan Shepherd

Reburying World Heritage human remains would close window on Barkandji past pp. 19-19

Michael Westaway, Warren Clark, Doug Williams and Gerald Quayle

Hit movie reveals how a tuberculosis drug halts ATP synthesis pp. 21-22

Valerie Mizrahi and Clifton E. Barry

Machine learning reveals the complexity of dense amorphous silicon pp. 22-23

Paul F. McMillan

A screen of brain organoids to study neurodevelopmental disease pp. 24-25

Adriana Cherskov and Nenad Sestan

Artificial intelligence accelerated by light pp. 25-26

Huaqiang Wu and Qionghai Dai

Big data and simple models used to track the spread of COVID-19 in cities pp. 26-28

Kevin C. Ma and Marc Lipsitch

Core-collapse supernova explosion theory pp. 29-39

A. Burrows and D. Vartanyan

Competing magnetic orders in a bilayer Hubbard model with ultracold atoms pp. 40-43

Marcell Gall, Nicola Wurz, Jens Samland, Chun Fai Chan and Michael Köhl

11 TOPS photonic convolutional accelerator for optical neural networks pp. 44-51

Xingyuan Xu, Mengxi Tan, Bill Corcoran, Jiayang Wu, Andreas Boes, Thach G. Nguyen, Sai T. Chu, Brent E. Little, Damien G. Hicks, Roberto Morandotti, Arnan Mitchell and David J. Moss

Parallel convolutional processing using an integrated photonic tensor core pp. 52-58

J. Feldmann, N. Youngblood, M. Karpov, H. Gehring, X. Li, M. Stappers, M. Gallo, X. Fu, A. Lukashchuk, A. S. Raja, J. Liu, C. D. Wright, A. Sebastian, T. J. Kippenberg, W. H. P. Pernice and H. Bhaskaran

Origins of structural and electronic transitions in disordered silicon pp. 59-64

Volker L. Deringer, Noam Bernstein, Gábor Csányi, Chiheb Mahmoud, Michele Ceriotti, Mark Wilson, David A. Drabold and Stephen R. Elliott

Single-defect phonons imaged by electron microscopy pp. 65-69

Xingxu Yan, Chengyan Liu, Chaitanya A. Gadre, Lei Gu, Toshihiro Aoki, Tracy C. Lovejoy, Niklas Dellby, Ondrej L. Krivanek, Darrell G. Schlom, Ruqian Wu and Xiaoqing Pan

Poleward and weakened westerlies during Pliocene warmth pp. 70-75

Jordan T. Abell, Gisela Winckler, Robert F. Anderson and Timothy D. Herbert

Drivers and dynamics of a massive adaptive radiation in cichlid fishes pp. 76-81

Fabrizia Ronco, Michael Matschiner, Astrid Böhne, Anna Boila, Heinz H. Büscher, Athimed El Taher, Adrian Indermaur, Milan Malinsky, Virginie Ricci, Ansgar Kahmen, Sissel Jentoft and Walter Salzburger

Mobility network models of COVID-19 explain inequities and inform reopening pp. 82-87

Serina Chang, Emma Pierson, Pang Wei Koh, Jaline Gerardin, Beth Redbird, David Grusky and Jure Leskovec

Neuronal diversity and convergence in a visual system developmental atlas pp. 88-95

Mehmet Neset Özel, Félix Simon, Shadi Jafari, Isabel Holguera, Yen-Chung Chen, Najate Benhra, Rana Naja El-Danaf, Katarina Kapuralin, Jennifer Amy Malin, Nikolaos Konstantinides and Claude Desplan

Coupling of hippocampal theta and ripples with pontogeniculooccipital waves pp. 96-102

Juan F. Ramirez-Villegas, Michel Besserve, Yusuke Murayama, Henry C. Evrard, Axel Oeltermann and Nikos K. Logothetis

TRF2-independent chromosome end protection during pluripotency pp. 103-109

Phil Ruis, David Ly, Valerie Borel, Georgia R. Kafer, Afshan McCarthy, Steven Howell, Robert Blassberg, Ambrosius P. Snijders, James Briscoe, Kathy K. Niakan, Paulina Marzec, Anthony J. Cesare and Simon J. Boulton

TRF2-mediated telomere protection is dispensable in pluripotent stem cells pp. 110-115

Marta Markiewicz-Potoczny, Anastasia Lobanova, Anisha M. Loeb, Oktay Kirak, Teresa Olbrich, Sergio Ruiz and Eros Lazzerini Denchi

A network of transcriptional repressors modulates auxin responses pp. 116-119

Jekaterina Truskina, Jingyi Han, Elina Chrysanthou, Carlos S. Galvan-Ampudia, Stéphanie Lainé, Géraldine Brunoud, Julien Macé, Simon Bellows, Jonathan Legrand, Anne-Maarit Bågman, Margot E. Smit, Ondřej Smetana, Arnaud Stigliani, Silvana Porco, Malcolm J. Bennett, Ari Pekka Mähönen, François Parcy, Etienne Farcot, Francois Roudier, Siobhan M. Brady, Anthony Bishopp and Teva Vernoux

Prokaryotic viperins produce diverse antiviral molecules pp. 120-124

Aude Bernheim, Adi Millman, Gal Ofir, Gilad Meitav, Carmel Avraham, Helena Shomar, Masha M. Rosenberg, Nir Tal, Sarah Melamed, Gil Amitai and Rotem Sorek

The coding capacity of SARS-CoV-2 pp. 125-130

Yaara Finkel, Orel Mizrahi, Aharon Nachshon, Shira Weingarten-Gabbay, David Morgenstern, Yfat Yahalom-Ronen, Hadas Tamir, Hagit Achdout, Dana Stein, Ofir Israeli, Adi Beth-Din, Sharon Melamed, Shay Weiss, Tomer Israely, Nir Paran, Michal Schwartz and Noam Stern-Ginossar

Commensal-driven immune zonation of the liver promotes host defence pp. 131-136

Anita Gola, Michael G. Dorrington, Emily Speranza, Claudia Sala, Rochelle M. Shih, Andrea J. Radtke, Harikesh S. Wong, Antonio P. Baptista, Jonathan M. Hernandez, Gastone Castellani, Iain D. C. Fraser and Ronald N. Germain

RNA nucleation by MSL2 induces selective X chromosome compartmentalization pp. 137-142

Claudia Isabelle Keller Valsecchi, M. Felicia Basilicata, Plamen Georgiev, Aline Gaub, Janine Seyfferth, Tanvi Kulkarni, Amol Panhale, Giuseppe Semplicio, Vinitha Manjunath, Herbert Holz, Pouria Dasmeh and Asifa Akhtar

Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline pp. 143-147

Hui Guo, Gautier M. Courbon, Stephanie A. Bueler, Juntao Mai, Jun Liu and John L. Rubinstein

Structure of the class D GPCR Ste2 dimer coupled to two G proteins pp. 148-153

Vaithish Velazhahan, Ning Ma, Gáspár Pándy-Szekeres, Albert J. Kooistra, Yang Lee, David E. Gloriam, Nagarajan Vaidehi and Christopher G. Tate

Rethinking travel in a post-pandemic world pp. 155-157

Josie Glausiusz

What’s your risk of catching COVID? These tools help you to find out pp. 158-159

Michael Eisenstein

Travails of an intrepid platypus counter pp. 162-162

Virginia Gewin